HK1115376A1 - Inhibitors of mitotic kinesins and their therapeutical use - Google Patents
Inhibitors of mitotic kinesins and their therapeutical useInfo
- Publication number
- HK1115376A1 HK1115376A1 HK08105389.0A HK08105389A HK1115376A1 HK 1115376 A1 HK1115376 A1 HK 1115376A1 HK 08105389 A HK08105389 A HK 08105389A HK 1115376 A1 HK1115376 A1 HK 1115376A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- inhibitors
- mitotic kinesins
- therapeutical use
- therapeutical
- kinesins
- Prior art date
Links
- 102000010638 Kinesin Human genes 0.000 title 1
- 108010063296 Kinesin Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000000394 mitotic effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C07F9/65392—Five-membered rings containing two nitrogen atoms
- C07F9/65395—Five-membered rings containing two nitrogen atoms having the two nitrogen atoms in positions 1 and 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67689005P | 2005-05-02 | 2005-05-02 | |
| PCT/US2006/016526 WO2006119146A1 (en) | 2005-05-02 | 2006-05-01 | Mitotic kinesin inhibitors and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1115376A1 true HK1115376A1 (en) | 2008-11-28 |
Family
ID=37308299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK08105389.0A HK1115376A1 (en) | 2005-05-02 | 2008-05-15 | Inhibitors of mitotic kinesins and their therapeutical use |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US7795282B2 (xx) |
| EP (1) | EP1879886B1 (xx) |
| JP (1) | JP2008540418A (xx) |
| KR (1) | KR101329901B1 (xx) |
| CN (1) | CN101248068A (xx) |
| AU (1) | AU2006242380A1 (xx) |
| BR (1) | BRPI0610193A2 (xx) |
| CA (1) | CA2606708C (xx) |
| HK (1) | HK1115376A1 (xx) |
| IL (1) | IL186707A (xx) |
| MX (1) | MX2007013539A (xx) |
| NO (1) | NO20076186L (xx) |
| RU (1) | RU2007144612A (xx) |
| TW (1) | TW200716153A (xx) |
| UA (1) | UA95907C2 (xx) |
| WO (1) | WO2006119146A1 (xx) |
| ZA (1) | ZA200710218B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7449486B2 (en) | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| UA95907C2 (xx) | 2005-05-02 | 2011-09-26 | Эррей Биофарма Инк. | Інгібітори мітотичних кінезинів та їх використання$ингибиторы митотических кинезинов и их использование |
| AR068888A1 (es) * | 2007-10-19 | 2009-12-16 | Schering Corp | Derivados de 1, 3, 4 - tiadiazol, una composicion farmaceutica que los comprende y su uso en la preparacion de medicamentos para el tratamiento de enfermedades mediadas por la inhibicion de la quinesina ksp. |
| US9561214B2 (en) * | 2008-10-16 | 2017-02-07 | Array Biopharma Inc. | Method of treatment using inhibitors of mitosis |
| DE102009058280A1 (de) * | 2009-12-14 | 2011-06-16 | Merck Patent Gmbh | Thiazolderivate |
| EP2455456A1 (en) | 2010-11-22 | 2012-05-23 | Institut Curie | Use of kinesin inhibitors in HIV infection treatment and a method for screening them |
| WO2016094307A1 (en) | 2014-12-08 | 2016-06-16 | The Research Foundation For The State University Of New York | Anti-fungals targeting the synthesis of fungal shingolipids |
| WO2018232298A1 (en) | 2017-06-16 | 2018-12-20 | The Research Foundation For The State University Of New York | Anti-fungals compounds targeting the synthesis of fungal sphingolipids |
| US20230286970A1 (en) * | 2020-08-07 | 2023-09-14 | Italfarmaco S.P.A. | Novel oxadiazole-based selective hdac6 inhibitors |
| CN114014824B (zh) * | 2020-12-09 | 2023-06-13 | 上海科技大学 | 一种杂环化合物的应用 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2702803A (en) * | 1954-04-12 | 1955-02-22 | Lilly Co Eli | Substituted heterodiazoles |
| EP0217519B1 (en) * | 1985-08-31 | 1992-02-05 | FISONS plc | 5-membered heterocyclic ring angiotensin converting enzyme inhibitors |
| GB8625774D0 (en) * | 1986-10-28 | 1986-12-03 | Reckitt & Colmann Prod Ltd | Thiadiazole derivative |
| JPH0572686A (ja) | 1991-09-11 | 1993-03-26 | Konica Corp | ハロゲン化銀写真感光材料 |
| AU4288293A (en) * | 1992-04-27 | 1993-11-29 | E.I. Du Pont De Nemours And Company | Fungicidal 1,3,4-oxadiazines and 1,3,4-thiadiazines |
| US6159938A (en) * | 1994-11-21 | 2000-12-12 | Cortech, Inc. | Serine protease inhibitors comprising α-keto heterocycles |
| JPH10513443A (ja) * | 1995-02-02 | 1998-12-22 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５ＨＴ▲下２ｃ▼レセプターアンタゴニスト活性を有する複素環化合物 |
| US5958957A (en) * | 1996-04-19 | 1999-09-28 | Novo Nordisk A/S | Modulators of molecules with phosphotyrosine recognition units |
| US5668159A (en) * | 1996-05-08 | 1997-09-16 | The Dupont Merck Pharmaceutical Company | 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as IIb/IIIa antagonists |
| AR011164A1 (es) | 1997-02-28 | 2000-08-02 | Lilly Co Eli | Compuestos heterociclicos, composiciones farmaceuticas que los comprenden, y metodos para inhibir la liberacion del peptido beta-amiloide y/o su sintesismediante el uso de dichos compuestos |
| AU759619B2 (en) * | 1997-12-16 | 2003-04-17 | Warner-Lambert Company | Novel amines as pharmaceutical agents |
| US6235762B1 (en) * | 1998-11-23 | 2001-05-22 | American Cyanamid Company | 2-aryl-Δ2-1,3,4-(oxa and thia)diazoline insecticidal and acaricidal agents |
| JP2000159756A (ja) | 1998-11-23 | 2000-06-13 | American Cyanamid Co | ２―アリ―ル―δ２―１，３，４―（オキサおよびチア）ジアゾリン殺虫および殺ダニ剤 |
| US20020002193A1 (en) * | 1999-03-25 | 2002-01-03 | Yu Dingwei Tim | Thiadiazole antifungal agents |
| WO2001056994A1 (en) | 2000-02-04 | 2001-08-09 | Biogen, Inc. | Integrin antagonists |
| WO2003018008A1 (fr) * | 2000-02-25 | 2003-03-06 | Shionogi & Co., Ltd. | Agent d'accélération de l'expression de apo ai |
| US6284480B1 (en) | 2000-04-03 | 2001-09-04 | Cytokinetics, Inc. | Antifungal assay |
| RU2004116063A (ru) * | 2001-10-22 | 2005-03-27 | Аутсайд Ин (CH) | Тара и тарное устройство для сигарет |
| WO2003051854A1 (en) * | 2001-12-11 | 2003-06-26 | Kyowa Hakko Kogyo Co., Ltd. | Thiadiazoline derivative |
| AU2003249597B2 (en) * | 2002-03-08 | 2007-06-28 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| US20050004186A1 (en) * | 2002-12-20 | 2005-01-06 | Pfizer Inc | MEK inhibiting compounds |
| US20040167188A1 (en) * | 2003-02-14 | 2004-08-26 | Zhili Xin | Protein-tyrosine phosphatase inhibitors and uses thereof |
| US7521447B2 (en) | 2003-03-03 | 2009-04-21 | Array Biopharma Inc. | P38 inhibitors and methods of use thereof |
| AU2004230799B2 (en) * | 2003-04-18 | 2010-03-18 | Fujifilm Corporation | Mitotic kinesin inhibitor |
| US7115642B2 (en) * | 2003-05-02 | 2006-10-03 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection |
| EP1620412A2 (en) * | 2003-05-02 | 2006-02-01 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds and hydro isomers thereof |
| US7244739B2 (en) * | 2003-05-14 | 2007-07-17 | Torreypines Therapeutics, Inc. | Compounds and uses thereof in modulating amyloid beta |
| US20050075375A1 (en) * | 2003-05-14 | 2005-04-07 | Anadys Pharmaceuticals, Inc. | Heterocyclic compounds for treating hepatitis C virus |
| WO2005000308A2 (en) * | 2003-05-15 | 2005-01-06 | Rigel Pharmaceuticals, Inc. | Methods of identifying hcv ns5b polymerase inhibitors and use against hepatitis c |
| US7220745B2 (en) * | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
| WO2004111024A1 (ja) | 2003-06-10 | 2004-12-23 | Kyowa Hakko Kogyo Co., Ltd. | チアジアゾリン誘導体 |
| WO2004111023A1 (ja) | 2003-06-10 | 2004-12-23 | Kyowa Hakko Kogyo Co., Ltd. | チアジアゾリン－１－オキシド誘導体 |
| EP1656133A4 (en) | 2003-08-15 | 2008-10-29 | Merck & Co Inc | INHIBITORS OF MITOTIC KINESINE |
| CA2542034A1 (en) | 2003-10-10 | 2005-04-21 | Kyowa Hakko Kogyo Co., Ltd. | Thiadiazoline derivatives |
| JP2005232016A (ja) | 2004-02-17 | 2005-09-02 | Kyowa Hakko Kogyo Co Ltd | オキサジアゾリン誘導体 |
| GB0406867D0 (en) | 2004-03-26 | 2004-04-28 | F2G Ltd | Antifungal agents |
| WO2006031348A2 (en) | 2004-08-18 | 2006-03-23 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
| US7449486B2 (en) * | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| CA2584802A1 (en) * | 2004-11-10 | 2006-05-18 | Basf Aktiengesellschaft | A method of regenerating a catalyst |
| UA95907C2 (xx) | 2005-05-02 | 2011-09-26 | Эррей Биофарма Инк. | Інгібітори мітотичних кінезинів та їх використання$ингибиторы митотических кинезинов и их использование |
| CN101553476A (zh) | 2006-10-03 | 2009-10-07 | 阵列生物制药公司 | 作为有丝分裂驱动蛋白抑制剂的二唑和噻二唑衍生物及其使用方法 |
| US10174390B2 (en) | 2006-10-03 | 2019-01-08 | Gary M. Cola, JR. | Microtreatment of iron-based alloy, apparatus and method therefor, and articles resulting therefrom |
-
2006
- 2006-01-05 UA UAA200713355A patent/UA95907C2/ru unknown
- 2006-05-01 AU AU2006242380A patent/AU2006242380A1/en not_active Abandoned
- 2006-05-01 WO PCT/US2006/016526 patent/WO2006119146A1/en active Application Filing
- 2006-05-01 BR BRPI0610193-3A patent/BRPI0610193A2/pt not_active IP Right Cessation
- 2006-05-01 JP JP2008510090A patent/JP2008540418A/ja active Pending
- 2006-05-01 US US11/415,455 patent/US7795282B2/en not_active Expired - Fee Related
- 2006-05-01 MX MX2007013539A patent/MX2007013539A/es not_active Application Discontinuation
- 2006-05-01 RU RU2007144612/04A patent/RU2007144612A/ru not_active Application Discontinuation
- 2006-05-01 CA CA2606708A patent/CA2606708C/en not_active Expired - Fee Related
- 2006-05-01 KR KR1020077027972A patent/KR101329901B1/ko active IP Right Grant
- 2006-05-01 EP EP06758821.0A patent/EP1879886B1/en active Active
- 2006-05-01 CN CNA2006800242288A patent/CN101248068A/zh active Pending
- 2006-05-02 TW TW095115570A patent/TW200716153A/zh unknown
-
2007
- 2007-10-17 IL IL186707A patent/IL186707A/en active IP Right Grant
- 2007-11-27 ZA ZA200710218A patent/ZA200710218B/xx unknown
- 2007-11-30 NO NO20076186A patent/NO20076186L/no not_active Application Discontinuation
-
2008
- 2008-05-15 HK HK08105389.0A patent/HK1115376A1/xx not_active IP Right Cessation
-
2010
- 2010-06-23 US US12/822,066 patent/US8268871B2/en active Active
-
2012
- 2012-08-15 US US13/586,355 patent/US8580828B2/en active Active
-
2013
- 2013-09-19 US US14/031,958 patent/US20140018399A1/en not_active Abandoned
-
2015
- 2015-03-19 US US14/663,286 patent/US9221841B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW200716153A (en) | 2007-05-01 |
| IL186707A0 (en) | 2008-02-09 |
| JP2008540418A (ja) | 2008-11-20 |
| US8580828B2 (en) | 2013-11-12 |
| ZA200710218B (en) | 2009-07-29 |
| IL186707A (en) | 2013-04-30 |
| US7795282B2 (en) | 2010-09-14 |
| AU2006242380A1 (en) | 2006-11-09 |
| RU2007144612A (ru) | 2009-06-10 |
| KR20080003934A (ko) | 2008-01-08 |
| US8268871B2 (en) | 2012-09-18 |
| EP1879886A1 (en) | 2008-01-23 |
| US20100331283A1 (en) | 2010-12-30 |
| AU2006242380A2 (en) | 2008-07-03 |
| KR101329901B1 (ko) | 2013-11-14 |
| EP1879886B1 (en) | 2014-07-09 |
| BRPI0610193A2 (pt) | 2010-06-01 |
| MX2007013539A (es) | 2008-01-24 |
| UA95907C2 (xx) | 2011-09-26 |
| US20060247178A1 (en) | 2006-11-02 |
| CA2606708C (en) | 2015-01-06 |
| CA2606708A1 (en) | 2006-11-09 |
| EP1879886A4 (en) | 2010-09-08 |
| NO20076186L (no) | 2008-02-01 |
| CN101248068A (zh) | 2008-08-20 |
| US20140018399A1 (en) | 2014-01-16 |
| WO2006119146A1 (en) | 2006-11-09 |
| US20130109656A1 (en) | 2013-05-02 |
| US9221841B2 (en) | 2015-12-29 |
| US20150191490A1 (en) | 2015-07-09 |
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