ZA200710218B - Mitotic kinesin inhibitors and methods of use thereof - Google Patents
Mitotic kinesin inhibitors and methods of use thereofInfo
- Publication number
- ZA200710218B ZA200710218B ZA200710218A ZA200710218A ZA200710218B ZA 200710218 B ZA200710218 B ZA 200710218B ZA 200710218 A ZA200710218 A ZA 200710218A ZA 200710218 A ZA200710218 A ZA 200710218A ZA 200710218 B ZA200710218 B ZA 200710218B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- mitotic kinesin
- kinesin inhibitors
- inhibitors
- mitotic
- Prior art date
Links
- 102000010638 Kinesin Human genes 0.000 title 1
- 108010063296 Kinesin Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000000394 mitotic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C07F9/65392—Five-membered rings containing two nitrogen atoms
- C07F9/65395—Five-membered rings containing two nitrogen atoms having the two nitrogen atoms in positions 1 and 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67689005P | 2005-05-02 | 2005-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200710218B true ZA200710218B (en) | 2009-07-29 |
Family
ID=37308299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200710218A ZA200710218B (en) | 2005-05-02 | 2007-11-27 | Mitotic kinesin inhibitors and methods of use thereof |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US7795282B2 (xx) |
| EP (1) | EP1879886B1 (xx) |
| JP (1) | JP2008540418A (xx) |
| KR (1) | KR101329901B1 (xx) |
| CN (1) | CN101248068A (xx) |
| AU (1) | AU2006242380A1 (xx) |
| BR (1) | BRPI0610193A2 (xx) |
| CA (1) | CA2606708C (xx) |
| HK (1) | HK1115376A1 (xx) |
| IL (1) | IL186707A (xx) |
| MX (1) | MX2007013539A (xx) |
| NO (1) | NO20076186L (xx) |
| RU (1) | RU2007144612A (xx) |
| TW (1) | TW200716153A (xx) |
| UA (1) | UA95907C2 (xx) |
| WO (1) | WO2006119146A1 (xx) |
| ZA (1) | ZA200710218B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7449486B2 (en) | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| UA95907C2 (xx) * | 2005-05-02 | 2011-09-26 | Эррей Биофарма Инк. | Інгібітори мітотичних кінезинів та їх використання$ингибиторы митотических кинезинов и их использование |
| BRPI0818605A2 (pt) * | 2007-10-19 | 2015-04-22 | Schering Corp | Derivados de 1,3,4-tiadiazl espiro-condensados para inibir a atividade de ksp cinesima |
| US9561214B2 (en) * | 2008-10-16 | 2017-02-07 | Array Biopharma Inc. | Method of treatment using inhibitors of mitosis |
| DE102009058280A1 (de) * | 2009-12-14 | 2011-06-16 | Merck Patent Gmbh | Thiazolderivate |
| EP2455456A1 (en) | 2010-11-22 | 2012-05-23 | Institut Curie | Use of kinesin inhibitors in HIV infection treatment and a method for screening them |
| US20180141897A1 (en) | 2014-12-08 | 2018-05-24 | The Research Foundation For The State University Of New York | Anti-fungals targeting the synthesis of fungal shingolipids |
| US11414378B2 (en) | 2017-06-16 | 2022-08-16 | The Research Foundation For The State University Of New York | Anti-fungals compounds targeting the synthesis of fungal sphingolipids |
| CN116157398A (zh) * | 2020-08-07 | 2023-05-23 | 意大发马克股份公司 | 作为组蛋白去乙酰化酶6(HDAC6)的选择性抑制剂用于治疗例如周围神经病变的2-(4-((5-(苯并[b]噻吩-3-基)-1H-四唑-1-基)甲基)苯基)-5-(二氟甲基)-1,3,4-噁二唑衍生物和类似化合物 |
| CN114014824B (zh) * | 2020-12-09 | 2023-06-13 | 上海科技大学 | 一种杂环化合物的应用 |
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| US2702803A (en) | 1954-04-12 | 1955-02-22 | Lilly Co Eli | Substituted heterodiazoles |
| EP0217519B1 (en) | 1985-08-31 | 1992-02-05 | FISONS plc | 5-membered heterocyclic ring angiotensin converting enzyme inhibitors |
| GB8625774D0 (en) | 1986-10-28 | 1986-12-03 | Reckitt & Colmann Prod Ltd | Thiadiazole derivative |
| JPH0572686A (ja) | 1991-09-11 | 1993-03-26 | Konica Corp | ハロゲン化銀写真感光材料 |
| WO1993022311A1 (en) * | 1992-04-27 | 1993-11-11 | E.I. Du Pont De Nemours And Company | Fungicidal 1,3,4-oxadiazines and 1,3,4-thiadiazines |
| US6159938A (en) | 1994-11-21 | 2000-12-12 | Cortech, Inc. | Serine protease inhibitors comprising α-keto heterocycles |
| WO1996023769A2 (en) | 1995-02-02 | 1996-08-08 | Smithkline Beecham Plc | Heterocyclic compounds possessing 5ht2c receptor antagonist activity |
| US5958957A (en) | 1996-04-19 | 1999-09-28 | Novo Nordisk A/S | Modulators of molecules with phosphotyrosine recognition units |
| US5668159A (en) | 1996-05-08 | 1997-09-16 | The Dupont Merck Pharmaceutical Company | 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as IIb/IIIa antagonists |
| HRP980093A2 (en) | 1997-02-28 | 1998-12-31 | Lilly Co Eli | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting "beta"-amyloid peptide release and/or its synthesis by use of such compounds |
| DK1045839T3 (da) | 1997-12-16 | 2004-07-05 | Warner Lambert Co | Hidtil ukendte aminer som farmaceutiske midler |
| US6235762B1 (en) | 1998-11-23 | 2001-05-22 | American Cyanamid Company | 2-aryl-Δ2-1,3,4-(oxa and thia)diazoline insecticidal and acaricidal agents |
| JP2000159756A (ja) | 1998-11-23 | 2000-06-13 | American Cyanamid Co | ２―アリ―ル―δ２―１，３，４―（オキサおよびチア）ジアゾリン殺虫および殺ダニ剤 |
| US6277873B1 (en) | 1999-03-25 | 2001-08-21 | Dingwei Tim Yu | Oxadiazole antifungal agents |
| AU2001234741A1 (en) | 2000-02-04 | 2001-08-14 | Biogen, Inc. | Integrin antagonists |
| US6284480B1 (en) | 2000-04-03 | 2001-09-04 | Cytokinetics, Inc. | Antifungal assay |
| US20040248950A1 (en) | 2001-08-24 | 2004-12-09 | Natsuki Ishizuka | Apo ai expression accelerating agent |
| WO2003035512A1 (en) * | 2001-10-22 | 2003-05-01 | Outside In | Self dispensing cigarette pack |
| WO2003051854A1 (en) | 2001-12-11 | 2003-06-26 | Kyowa Hakko Kogyo Co., Ltd. | Thiadiazoline derivative |
| ATE448207T1 (de) | 2002-03-08 | 2009-11-15 | Merck & Co Inc | Mitotische kinesin-hemmer |
| US20050004186A1 (en) | 2002-12-20 | 2005-01-06 | Pfizer Inc | MEK inhibiting compounds |
| US20040167188A1 (en) | 2003-02-14 | 2004-08-26 | Zhili Xin | Protein-tyrosine phosphatase inhibitors and uses thereof |
| JP4617299B2 (ja) | 2003-03-03 | 2011-01-19 | アレイ バイオファーマ、インコーポレイテッド | ｐ３８阻害剤及びその使用法 |
| CA2522594C (en) | 2003-04-18 | 2012-01-24 | Kyowa Hakko Kogyo Co., Ltd. | Mitotic kinesin inhibitor |
| EP1620412A2 (en) | 2003-05-02 | 2006-02-01 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds and hydro isomers thereof |
| WO2004099164A1 (en) | 2003-05-02 | 2004-11-18 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection |
| WO2004110351A2 (en) | 2003-05-14 | 2004-12-23 | Anadys Pharmaceuticals, Inc. | Heterocyclic compounds for treating hepatitis c virus |
| EP1628666B1 (en) | 2003-05-14 | 2015-09-23 | NeuroGenetic Pharmaceuticals, Inc. | Compouds and uses thereof in modulating amyloid beta |
| US7220745B2 (en) | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
| WO2005000308A2 (en) | 2003-05-15 | 2005-01-06 | Rigel Pharmaceuticals, Inc. | Methods of identifying hcv ns5b polymerase inhibitors and use against hepatitis c |
| US20070276017A1 (en) | 2003-06-10 | 2007-11-29 | Chikara Murakata | Thiadiazoline Derivative |
| JPWO2004111023A1 (ja) | 2003-06-10 | 2006-07-27 | 協和醗酵工業株式会社 | チアジアゾリン−１−オキシド誘導体 |
| CN1835746A (zh) | 2003-08-15 | 2006-09-20 | 默克公司 | 有丝分裂驱动蛋白抑制剂 |
| EP1671957A4 (en) * | 2003-10-10 | 2007-03-14 | THIADIAZOLINDERIVATE | |
| JP2005232016A (ja) | 2004-02-17 | 2005-09-02 | Kyowa Hakko Kogyo Co Ltd | オキサジアゾリン誘導体 |
| GB0406867D0 (en) | 2004-03-26 | 2004-04-28 | F2G Ltd | Antifungal agents |
| JP2008510013A (ja) * | 2004-08-18 | 2008-04-03 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤 |
| US7449486B2 (en) | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| JP4976306B2 (ja) * | 2004-11-10 | 2012-07-18 | ビーエーエスエフ ソシエタス・ヨーロピア | 触媒の再生方法 |
| UA95907C2 (xx) | 2005-05-02 | 2011-09-26 | Эррей Биофарма Инк. | Інгібітори мітотичних кінезинів та їх використання$ингибиторы митотических кинезинов и их использование |
| WO2008042928A2 (en) | 2006-10-03 | 2008-04-10 | Array Biopharma, Inc. | Oxadiazole and thiadiazole derivatives as mitotic kinesin inhibitors and methods of use thereof |
| WO2008042982A2 (en) | 2006-10-03 | 2008-04-10 | Cola Jr Gary M | Microtreatment of iron-based alloy, apparatus and method therefor, and articles resulting therefrom |
-
2006
- 2006-01-05 UA UAA200713355A patent/UA95907C2/ru unknown
- 2006-05-01 KR KR1020077027972A patent/KR101329901B1/ko active IP Right Grant
- 2006-05-01 JP JP2008510090A patent/JP2008540418A/ja active Pending
- 2006-05-01 WO PCT/US2006/016526 patent/WO2006119146A1/en active Application Filing
- 2006-05-01 RU RU2007144612/04A patent/RU2007144612A/ru not_active Application Discontinuation
- 2006-05-01 US US11/415,455 patent/US7795282B2/en not_active Expired - Fee Related
- 2006-05-01 BR BRPI0610193-3A patent/BRPI0610193A2/pt not_active IP Right Cessation
- 2006-05-01 EP EP06758821.0A patent/EP1879886B1/en active Active
- 2006-05-01 CN CNA2006800242288A patent/CN101248068A/zh active Pending
- 2006-05-01 AU AU2006242380A patent/AU2006242380A1/en not_active Abandoned
- 2006-05-01 MX MX2007013539A patent/MX2007013539A/es not_active Application Discontinuation
- 2006-05-01 CA CA2606708A patent/CA2606708C/en not_active Expired - Fee Related
- 2006-05-02 TW TW095115570A patent/TW200716153A/zh unknown
-
2007
- 2007-10-17 IL IL186707A patent/IL186707A/en active IP Right Grant
- 2007-11-27 ZA ZA200710218A patent/ZA200710218B/xx unknown
- 2007-11-30 NO NO20076186A patent/NO20076186L/no not_active Application Discontinuation
-
2008
- 2008-05-15 HK HK08105389.0A patent/HK1115376A1/xx not_active IP Right Cessation
-
2010
- 2010-06-23 US US12/822,066 patent/US8268871B2/en not_active Expired - Fee Related
-
2012
- 2012-08-15 US US13/586,355 patent/US8580828B2/en active Active
-
2013
- 2013-09-19 US US14/031,958 patent/US20140018399A1/en not_active Abandoned
-
2015
- 2015-03-19 US US14/663,286 patent/US9221841B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO20076186L (no) | 2008-02-01 |
| HK1115376A1 (en) | 2008-11-28 |
| IL186707A (en) | 2013-04-30 |
| EP1879886A4 (en) | 2010-09-08 |
| US9221841B2 (en) | 2015-12-29 |
| MX2007013539A (es) | 2008-01-24 |
| CA2606708C (en) | 2015-01-06 |
| US20150191490A1 (en) | 2015-07-09 |
| US20060247178A1 (en) | 2006-11-02 |
| EP1879886B1 (en) | 2014-07-09 |
| US8268871B2 (en) | 2012-09-18 |
| WO2006119146A1 (en) | 2006-11-09 |
| CN101248068A (zh) | 2008-08-20 |
| JP2008540418A (ja) | 2008-11-20 |
| KR20080003934A (ko) | 2008-01-08 |
| US20100331283A1 (en) | 2010-12-30 |
| US7795282B2 (en) | 2010-09-14 |
| KR101329901B1 (ko) | 2013-11-14 |
| EP1879886A1 (en) | 2008-01-23 |
| TW200716153A (en) | 2007-05-01 |
| AU2006242380A1 (en) | 2006-11-09 |
| BRPI0610193A2 (pt) | 2010-06-01 |
| AU2006242380A2 (en) | 2008-07-03 |
| CA2606708A1 (en) | 2006-11-09 |
| US20130109656A1 (en) | 2013-05-02 |
| IL186707A0 (en) | 2008-02-09 |
| US8580828B2 (en) | 2013-11-12 |
| UA95907C2 (xx) | 2011-09-26 |
| US20140018399A1 (en) | 2014-01-16 |
| RU2007144612A (ru) | 2009-06-10 |
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