HK1111608A1 - Pharmaceutical composition comprising a solid dispersion with a polymer matrix - Google Patents

Pharmaceutical composition comprising a solid dispersion with a polymer matrix

Info

Publication number
HK1111608A1
HK1111608A1 HK08102568.0A HK08102568A HK1111608A1 HK 1111608 A1 HK1111608 A1 HK 1111608A1 HK 08102568 A HK08102568 A HK 08102568A HK 1111608 A1 HK1111608 A1 HK 1111608A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical composition
polymer matrix
solid dispersion
dispersion
solid
Prior art date
Application number
HK08102568.0A
Other languages
English (en)
Inventor
Michel Bedos
Thierry Breul
Stephen Byard
Dos Santos Isabel Ribeiro
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HK1111608A1 publication Critical patent/HK1111608A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK08102568.0A 2004-09-17 2008-03-05 Pharmaceutical composition comprising a solid dispersion with a polymer matrix HK1111608A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0409874A FR2875409B1 (fr) 2004-09-17 2004-09-17 Composition pharmaceutique comprenant une dispersion solide a matrice polymere comprenant une phase continue de polydextrose et une phase continue d'un polymere autre que du polydextrose
PCT/FR2005/002288 WO2006032762A2 (fr) 2004-09-17 2005-09-15 Composition pharmaceutique comprenant une dispersion solide a matrice polymere comprenant une phase continue de polydextrose et une phase continue d'un polymere autre que du polydextrose

Publications (1)

Publication Number Publication Date
HK1111608A1 true HK1111608A1 (en) 2008-08-15

Family

ID=34948358

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08102568.0A HK1111608A1 (en) 2004-09-17 2008-03-05 Pharmaceutical composition comprising a solid dispersion with a polymer matrix

Country Status (18)

Country Link
US (1) US9084730B2 (xx)
EP (1) EP1791524B1 (xx)
JP (1) JP5224812B2 (xx)
KR (1) KR101342193B1 (xx)
CN (2) CN101039657B (xx)
AU (1) AU2005286396B2 (xx)
BR (1) BRPI0515390A (xx)
CA (1) CA2579673C (xx)
EA (1) EA012850B1 (xx)
FR (1) FR2875409B1 (xx)
HK (1) HK1111608A1 (xx)
IL (1) IL181773A0 (xx)
MA (1) MA28858B1 (xx)
MX (1) MX2007003162A (xx)
NO (1) NO20071853L (xx)
NZ (1) NZ553780A (xx)
WO (1) WO2006032762A2 (xx)
ZA (1) ZA200702214B (xx)

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CA2609659C (en) 2005-05-26 2014-01-28 Neuron Systems, Inc. Azanaphthalenes, compositions and methods for treating retinal disease
RU2457841C2 (ru) * 2006-02-09 2012-08-10 Мерк Шарп Энд Домэ Корп. Полимерные композиции ингибиторов сетр
WO2008135852A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Pharmaceutical compositions comprising nanoparticles and casein
FR2921835B1 (fr) * 2007-10-05 2012-05-04 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Composition d'enrobage comprenant du polydextrose, procede pour sa preparation et utilisation pour enrober les formes solides ingerables
PE20091809A1 (es) 2008-04-17 2009-12-03 Sanofi Aventis Uso de dronedarona para la preparacion de un medicamento para uso en la prevencion de la hospitalizacion cardiovascular o de la mortalidad
FR2930149B1 (fr) * 2008-04-17 2011-02-18 Sanofi Aventis Association de dronedarone avec au moins un diuretique, son application en therapeutique
EP2116239A1 (en) * 2008-04-29 2009-11-11 Sanofi-Aventis Method for managing the risks associated with an increase in serum creatinine during dronedarone treatment
US8728516B2 (en) * 2009-04-30 2014-05-20 Abbvie Inc. Stabilized lipid formulation of apoptosis promoter
TWI532484B (zh) * 2009-06-08 2016-05-11 艾伯維有限公司 包含凋亡促進劑之固態分散劑
TWI540132B (zh) * 2009-06-08 2016-07-01 亞培公司 Ｂｃｌ-２族群抑制劑之口服醫藥劑型
CN102078307B (zh) * 2009-12-01 2012-11-07 天津市汉康医药生物技术有限公司 一种盐酸决奈达隆固体分散体的药物组合物及其制备方法
WO2011135582A2 (en) 2010-04-28 2011-11-03 Cadila Healthcare Limited Pharmaceutical compositions of dronedarone
WO2011135581A2 (en) 2010-04-28 2011-11-03 Cadila Healthcare Limited Pharmaceutical compositions of dronedarone
EP2571526B1 (en) 2010-05-17 2019-03-13 Novaer Holdings, Inc. Drug delivery devices for delivery of ocular therapeutic agents
WO2012001673A1 (en) * 2010-06-28 2012-01-05 Mapi Pharma Holdings (Cyprus) Limited Amorphous form of dronedarone
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
CN102342907A (zh) 2010-07-30 2012-02-08 江苏恒瑞医药股份有限公司 决奈达隆固体分散体及其制备方法
US20130142849A1 (en) 2010-08-17 2013-06-06 Lupin Limited Controlled release formulations of dronedarone
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
US9204667B2 (en) * 2010-12-01 2015-12-08 R.J. Reynolds Tobacco Company Smokeless tobacco pastille and injection molding process for forming smokeless tobacco products
WO2013024411A1 (en) 2011-08-12 2013-02-21 Lupin Limited Co-milled formulation of dronedarone
EP2817001A1 (en) 2012-02-20 2014-12-31 Lupin Limited Bilayer tablet of dronedarone
CN103054820B (zh) * 2012-08-22 2016-07-13 石药集团中奇制药技术（石家庄）有限公司 一种盐酸决奈达隆药物组合物及其制备方法
AU2014209387B2 (en) 2013-01-23 2018-11-01 Aldeyra Therapeutics, Inc. Toxic aldehyde related diseases and treatment
WO2014120981A1 (en) 2013-01-31 2014-08-07 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
PL3038601T3 (pl) 2013-08-27 2020-08-24 Gilead Pharmasset Llc Formulacja złożona dwóch związków przeciwwirusowych
TWI721947B (zh) 2014-06-11 2021-03-21 美商基利法瑪席特有限責任公司 抗病毒化合物的固態形式
RU2019109633A (ru) * 2016-09-09 2020-10-09 Мерк Патент Гмбх Способ изготовления твердой фармацевтической лекарственной формы
WO2019075136A1 (en) 2017-10-10 2019-04-18 Aldeyra Therapeutics, Inc. TREATMENT OF INFLAMMATORY DISORDERS
WO2020198064A1 (en) 2019-03-26 2020-10-01 Aldeyra Therapeutics, Inc. Ophthalmic formulations and uses thereof
JP2023526016A (ja) * 2020-05-13 2023-06-20 アルデイラ セラピューティクス， インコーポレイテッド 医薬製剤およびその使用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
GB8613689D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US5456932A (en) * 1987-04-20 1995-10-10 Fuisz Technologies Ltd. Method of converting a feedstock to a shearform product and product thereof
CA2095776C (en) * 1992-05-12 2007-07-10 Richard C. Fuisz Rapidly dispersable compositions containing polydextrose
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5935600A (en) * 1993-09-10 1999-08-10 Fuisz Technologies Ltd. Process for forming chewable quickly dispersing comestible unit and product therefrom
TW487582B (en) * 1995-08-11 2002-05-21 Nissan Chemical Ind Ltd Method for converting sparingly water-soluble medical substance to amorphous state
FR2761266B1 (fr) * 1997-03-28 1999-07-02 Sanofi Sa Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
DE19938672C2 (de) 1999-08-06 2001-11-22 Biop Biopolymer Gmbh Verfahren zur Herstellung einer thermoplastischen Polymermischung auf Stärkebasis durch reaktive Extrusion
EP1401503B1 (en) * 2001-06-22 2007-05-09 Pfizer Products Inc. Pharmaceutical compositions containing a solid dispersion of a poorly-soluble drug and a solubility-enhancing polymer
US6566347B1 (en) * 2001-08-22 2003-05-20 Duquesne University Of The Holy Ghost Controlled release pharmaceutical

Also Published As

Publication number Publication date
MX2007003162A (es) 2007-05-16
BRPI0515390A (pt) 2008-07-22
CN102247601A (zh) 2011-11-23
MA28858B1 (fr) 2007-09-03
JP2008513421A (ja) 2008-05-01
CN101039657B (zh) 2012-07-18
KR20070055601A (ko) 2007-05-30
FR2875409A1 (fr) 2006-03-24
CN101039657A (zh) 2007-09-19
WO2006032762A2 (fr) 2006-03-30
EA012850B1 (ru) 2009-12-30
EP1791524A2 (fr) 2007-06-06
IL181773A0 (en) 2007-07-04
NO20071853L (no) 2007-06-15
CA2579673C (fr) 2014-11-18
EP1791524B1 (fr) 2014-11-19
CA2579673A1 (fr) 2006-03-30
WO2006032762A3 (fr) 2006-06-01
NZ553780A (en) 2010-08-27
ZA200702214B (en) 2008-09-25
JP5224812B2 (ja) 2013-07-03
US20070243257A1 (en) 2007-10-18
US9084730B2 (en) 2015-07-21
KR101342193B1 (ko) 2013-12-16
AU2005286396A1 (en) 2006-03-30
AU2005286396B2 (en) 2011-08-11
FR2875409B1 (fr) 2010-05-07
EA200700658A1 (ru) 2007-08-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180910