HK1105632A1 - Derivatives of 1,4-diazabicyclo - Google Patents

Derivatives of 1,4-diazabicyclo

Info

Publication number
HK1105632A1
HK1105632A1 HK07110838.8A HK07110838A HK1105632A1 HK 1105632 A1 HK1105632 A1 HK 1105632A1 HK 07110838 A HK07110838 A HK 07110838A HK 1105632 A1 HK1105632 A1 HK 1105632A1
Authority
HK
Hong Kong
Prior art keywords
alkyl
alpha
definitions
diazacyclo
heterocyclylcarbonyl
Prior art date
Application number
HK07110838.8A
Other languages
English (en)
Inventor
Frederic Galli
Odile Leclerc
Alistair Lochead
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HK1105632A1 publication Critical patent/HK1105632A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
HK07110838.8A 2004-01-16 2007-10-05 Derivatives of 1,4-diazabicyclo HK1105632A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0400390A FR2865208B1 (fr) 2004-01-16 2004-01-16 Derives de 1,4-diazabicyclo[3.2.1]octanecarboxmique, leur preparation et leur application en therapeutique
PCT/FR2005/000027 WO2005077955A1 (fr) 2004-01-16 2005-01-07 Derives de 1,4-diazabicyclo[3.2.1]octanecarboxamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
HK1105632A1 true HK1105632A1 (en) 2008-02-22

Family

ID=34707894

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07110838.8A HK1105632A1 (en) 2004-01-16 2007-10-05 Derivatives of 1,4-diazabicyclo

Country Status (27)

Country Link
US (1) US7589201B2 (xx)
EP (1) EP1709052B1 (xx)
JP (1) JP4781279B2 (xx)
KR (1) KR101146445B1 (xx)
CN (1) CN1946726B (xx)
AT (1) ATE507228T1 (xx)
AU (1) AU2005212867B2 (xx)
BR (1) BRPI0506879A (xx)
CA (1) CA2549954C (xx)
CY (1) CY1111707T1 (xx)
DE (1) DE602005027659D1 (xx)
DK (1) DK1709052T3 (xx)
ES (1) ES2365141T3 (xx)
FR (1) FR2865208B1 (xx)
HK (1) HK1105632A1 (xx)
HR (1) HRP20110538T1 (xx)
IL (1) IL176702A (xx)
MA (1) MA28238A1 (xx)
NO (1) NO20063666L (xx)
NZ (1) NZ548046A (xx)
PL (1) PL1709052T3 (xx)
PT (1) PT1709052E (xx)
RS (1) RS51910B (xx)
RU (1) RU2361873C2 (xx)
SI (1) SI1709052T1 (xx)
WO (1) WO2005077955A1 (xx)
ZA (1) ZA200605823B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005243147A1 (en) * 2004-05-07 2005-11-24 Memory Pharmaceuticals Corporation 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
JP2008507518A (ja) 2004-07-22 2008-03-13 ピーティーシー セラピューティクス，インコーポレーテッド Ｃ型肝炎を治療するためのチエノピリジン
WO2006124897A2 (en) * 2005-05-13 2006-11-23 Lexicon Genetics Incorporated Methods and compositions for improving cognition
JP2009506036A (ja) * 2005-08-24 2009-02-12 レキシコン・ファーマシューティカルズ・インコーポレーテッド ピロロピリジン、ピロロピリミジンおよびピラゾロピリジン化合物、それらを含む組成物、ならびにそれらの使用方法
AR079980A1 (es) * 2010-01-13 2012-03-07 Sanofi Aventis Derivados de oxazolopirimidina sustituida en 2,5,7
JO3407B1 (ar) 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420521D0 (en) * 1994-10-12 1994-11-30 Smithkline Beecham Plc Novel compounds
GB9803411D0 (en) * 1998-02-18 1998-04-15 Smithkline Beecham Plc Novel compounds
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
WO2003044018A1 (en) * 2001-11-19 2003-05-30 Neurogen Corporation 1h-pyrrolo[3,2-b]pyridine-3-carboxylic acid amides
US6673811B1 (en) * 2001-11-19 2004-01-06 Neurogen Corporation 1H-pyrrolo [3,2-b] pyridine-3-carboxylic acid amines as GABAA receptor ligands
SE0202465D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
FR2845388B1 (fr) * 2002-10-08 2004-11-12 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2]nonanecarboxamides, leur preparation et leur application en therapeutique
US7456171B2 (en) * 2002-10-08 2008-11-25 Sanofi-Aventis 1,4-Diazabicyclo[3.2.2]nonanecarboxamide derivatives, preparation and therapeutic use thereof
TW200529860A (en) * 2003-12-22 2005-09-16 Astrazeneca Ab Nicotinic acetylcholine receptor ligands

Also Published As

Publication number Publication date
CA2549954A1 (fr) 2005-08-25
CN1946726A (zh) 2007-04-11
PL1709052T3 (pl) 2011-09-30
RU2006129633A (ru) 2008-02-27
AU2005212867B2 (en) 2011-05-12
CY1111707T1 (el) 2015-10-07
JP4781279B2 (ja) 2011-09-28
KR101146445B1 (ko) 2012-05-18
RU2361873C2 (ru) 2009-07-20
IL176702A (en) 2011-07-31
NO20063666L (no) 2006-10-11
AU2005212867A1 (en) 2005-08-25
US7589201B2 (en) 2009-09-15
ES2365141T3 (es) 2011-09-23
KR20070017990A (ko) 2007-02-13
FR2865208B1 (fr) 2009-01-16
EP1709052A1 (fr) 2006-10-11
DK1709052T3 (da) 2011-08-15
WO2005077955A1 (fr) 2005-08-25
CA2549954C (fr) 2013-04-23
NZ548046A (en) 2009-12-24
JP2007517838A (ja) 2007-07-05
PT1709052E (pt) 2011-07-20
ATE507228T1 (de) 2011-05-15
MA28238A1 (fr) 2006-10-02
CN1946726B (zh) 2011-08-31
ZA200605823B (en) 2008-01-08
HRP20110538T1 (hr) 2011-08-31
EP1709052B1 (fr) 2011-04-27
IL176702A0 (en) 2006-10-31
RS51910B (en) 2012-02-29
US20070155749A1 (en) 2007-07-05
SI1709052T1 (sl) 2011-08-31
BRPI0506879A (pt) 2007-06-12
DE602005027659D1 (de) 2011-06-09
FR2865208A1 (fr) 2005-07-22

Similar Documents

Publication Publication Date Title
HK1105632A1 (en) Derivatives of 1,4-diazabicyclo
AR054417A1 (es) Derivados de imidazol. proceso de obtencion y composiciones farmaceuticas.
AR074238A1 (es) Compuesto de n-{[(1r,4s,6r)-3-(2-piridinilcarbonil)-3-azabiciclo[4,1.0]hept-4-il]metil}-2-heteroarilamina, su uso para la preparacion de un medicamento util para el tratamiento de una enfermedad que requiere un antagonista del receptor de orexina humano y composicion farmaceutica que lo comprende
BRPI0707491B8 (pt) compostos úteis como agentes moduladores de receptores de mineralocorticóides, os referidos agentes compreendendo os mesmos e composições farmacêuticas
PE20091573A1 (es) Derivados heterociclicos de urea como inhibidores de adn girasa y/o topoisomerasa
WO2005118540A3 (en) Bicyclic, nitrogen-containing heterocycles as aromatase inhibitors
JP2011515483A5 (xx)
AR064197A1 (es) Derivados de pirimidina y piridina inhibidores de la proteina quinasa
CO5680435A2 (es) Derivados de quinazolina inhibidores de tirosina quinasa erbb y egb, su procedimiento de sintesis y composiciones farmaceuticas que los contienen
BRPI0407082B8 (pt) composto n-(4-(1-(2,6-difluorobenzil)-5-((dimetilamino)metil)-3-(6-metóxi-3-piridazinil)-2,4-dioxo-1,2,3,4-tetraidrotieno[2,3-d]pirimidina-6-il)fenil)-n’-metoxiuréia, ou um sal do mesmo, produto farmacêutico, e, uso do composto
RS50755B (sr) Supstituisani aril i heteroaril derivati kao modulatori metabolizma i profilakse i lečenje poremećaja proisteklih iz toga
AR054184A1 (es) Derivados de 1,5 difenilpirazol. procesos de obtencion y composiciones farmaceuticas.
GEP20094605B (en) Pyrazole derivatives, compositions containing such compounds and methods of use thereof
WO2005051946A3 (en) Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
AR056556A1 (es) Imidazo(1,2-a)piridina con actividad antiproliferacion celular
MX2008002805A (es) Derivados de carboxamida como antagonistas del receptor muscarinico.
HK1110868A1 (en) Heterocyclic compounds as ccr2b antagonists
WO2007103187A3 (en) 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists
AR062886A1 (es) Compuestos de tiazol pirazolopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento
WO2005118579A3 (en) Thiazole derivatives as chemokine receptor antagonists
AR063625A1 (es) COMPUESTOS HETEROCICLICOS eTILES COMO AGENTES ANTICANCEROSOS
PL1831202T3 (pl) Pochodne pirolidyniowe jako receptory M3 muskarynowe
WO2009044007A3 (fr) Dérivés de 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamides et de 2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]-diazépine-7-carboxamides, leur préparation et leur application en thérapeutique
WO2005100322A8 (en) Sulphur-linked imidazole compounds for the treament of hiv
PE20060495A1 (es) 4-(2,4-dicloro-5-metoxifenil)amino-6-metoxi-7-{[5-(amino-sustituido) metil]-3-furil}-3-quinolincarbonitrilos como inhibidores de quinasa

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160107