HK1105197A1 - Pyrimido-benzimidazole derivatives and the use thereof in the form of agonists or antagonists of melanocortin receptors - Google Patents

Pyrimido-benzimidazole derivatives and the use thereof in the form of agonists or antagonists of melanocortin receptors

Info

Publication number
HK1105197A1
HK1105197A1 HK07110478A HK07110478A HK1105197A1 HK 1105197 A1 HK1105197 A1 HK 1105197A1 HK 07110478 A HK07110478 A HK 07110478A HK 07110478 A HK07110478 A HK 07110478A HK 1105197 A1 HK1105197 A1 HK 1105197A1
Authority
HK
Hong Kong
Prior art keywords
pyrimido
benzimidazole derivatives
agonists
antagonists
melanocortin receptors
Prior art date
Application number
HK07110478A
Other languages
English (en)
Inventor
Poitout Lydie
Sackur Carole
Brault Valerie
Roubert Pierre
Plas Pascale
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of HK1105197A1 publication Critical patent/HK1105197A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Child & Adolescent Psychology (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
HK07110478A 2004-06-24 2007-09-27 Pyrimido-benzimidazole derivatives and the use thereof in the form of agonists or antagonists of melanocortin receptors HK1105197A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0406903A FR2872165B1 (fr) 2004-06-24 2004-06-24 Nouveaux derives de pyrimido-benzimidazole
PCT/FR2005/001563 WO2006010811A1 (fr) 2004-06-24 2005-06-22 Derives de pyrimido-benzimidazole et leur utilisation comme agonistes ou antagonistes des recepteurs des melanocortines

Publications (1)

Publication Number Publication Date
HK1105197A1 true HK1105197A1 (en) 2008-02-06

Family

ID=34948173

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07110478A HK1105197A1 (en) 2004-06-24 2007-09-27 Pyrimido-benzimidazole derivatives and the use thereof in the form of agonists or antagonists of melanocortin receptors

Country Status (13)

Country Link
US (2) US7763725B2 (de)
EP (1) EP1768985B1 (de)
JP (1) JP5033622B2 (de)
CN (1) CN1968955B (de)
AT (1) ATE384727T1 (de)
CA (1) CA2572121C (de)
DE (1) DE602005004547T2 (de)
ES (1) ES2301045T3 (de)
FR (1) FR2872165B1 (de)
HK (1) HK1105197A1 (de)
PT (1) PT1768985E (de)
RU (1) RU2392279C2 (de)
WO (1) WO2006010811A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2872165B1 (fr) 2004-06-24 2006-09-22 Sod Conseils Rech Applic Nouveaux derives de pyrimido-benzimidazole
US8314119B2 (en) 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
EP2072050A1 (de) 2007-12-21 2009-06-24 Santhera Pharmaceuticals (Schweiz) AG Komponenten mit anti-emetischer Wirkung
CN101333214A (zh) * 2008-08-05 2008-12-31 徐州师范大学 一种全氟烷基化的苯并［4,5］咪唑并［1,2-а］嘧啶类衍生物的合成方法
CN101717397B (zh) * 2008-10-09 2012-11-28 中国科学院上海药物研究所 一类取代吡啶并[2',1':2,3]咪唑并[4,5-c]异喹啉酮类化合物及其合成方法和用途,以及包含该类化合物的药物组合物
SG188307A1 (en) 2010-09-23 2013-04-30 Abbvie Inc Monohydrate of an azaadamantane derivative
US9018395B2 (en) 2011-01-27 2015-04-28 Université de Montréal Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators
HRP20211950T1 (hr) 2011-12-29 2022-03-18 Rhythm Pharmaceuticals, Inc. Postupak liječenja poremećaja u vezi sa melanokortin-4 receptorom u heterozigotnim nosiocima
CN102702056B (zh) * 2012-05-31 2014-09-24 北京师范大学 一种一锅法合成取代间苯二异硫氰酸酯的方法、合成的取代间苯二异硫氰酸酯化合物
CA2906694A1 (en) 2013-03-15 2014-09-18 Rhythm Metabolic, Inc. Peptide compositions
WO2014144842A2 (en) 2013-03-15 2014-09-18 Rhythm Metabolic, Inc. Pharmaceutical compositions
WO2016042775A1 (en) * 2014-09-18 2016-03-24 Sunovion Pharmaceuticals Inc. Tricyclic derivative
GB2548839B (en) * 2016-03-29 2021-02-24 Great Matter Pharma Ab New uses and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR406903A (fr) 1909-09-10 1910-02-15 Edwin Russell Perfectionnements aux protecteurs de bandages pneumatiques
ZW11781A1 (en) * 1980-06-27 1982-01-20 Hoffmann La Roche Pyrimidine derivatives
DK522187D0 (da) * 1987-10-06 1987-10-06 Ferrosan As Imidozothienopyrimidiner, deres fremstilling og anvendelse
US5212310A (en) * 1991-12-19 1993-05-18 Neurogen Corporation Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands
WO2001091752A1 (en) * 2000-05-30 2001-12-06 Merck & Co., Inc. Melanocortin receptor agonists
FR2872165B1 (fr) 2004-06-24 2006-09-22 Sod Conseils Rech Applic Nouveaux derives de pyrimido-benzimidazole

Also Published As

Publication number Publication date
JP5033622B2 (ja) 2012-09-26
PT1768985E (pt) 2008-04-18
US20100256135A1 (en) 2010-10-07
EP1768985B1 (de) 2008-01-23
DE602005004547D1 (de) 2008-03-13
JP2008503554A (ja) 2008-02-07
FR2872165B1 (fr) 2006-09-22
CN1968955A (zh) 2007-05-23
CN1968955B (zh) 2012-06-13
US8288395B2 (en) 2012-10-16
CA2572121C (fr) 2014-02-11
US7763725B2 (en) 2010-07-27
WO2006010811A1 (fr) 2006-02-02
EP1768985A1 (de) 2007-04-04
DE602005004547T2 (de) 2009-02-19
US20090209531A1 (en) 2009-08-20
FR2872165A1 (fr) 2005-12-30
RU2007102574A (ru) 2008-07-27
CA2572121A1 (fr) 2006-02-02
ATE384727T1 (de) 2008-02-15
ES2301045T3 (es) 2008-06-16
RU2392279C2 (ru) 2010-06-20

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150622