HK1101400A1 - Non-nucleotide reverse transcriptase inhibitors - Google Patents
Non-nucleotide reverse transcriptase inhibitorsInfo
- Publication number
- HK1101400A1 HK1101400A1 HK07109407.1A HK07109407A HK1101400A1 HK 1101400 A1 HK1101400 A1 HK 1101400A1 HK 07109407 A HK07109407 A HK 07109407A HK 1101400 A1 HK1101400 A1 HK 1101400A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- alkyl
- orx
- nrxrx
- reverse transcriptase
- transcriptase inhibitors
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title 1
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229940121357 antivirals Drugs 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400021A SE0400021D0 (sv) | 2004-01-08 | 2004-01-08 | Non-nucleoside reverse transcriptase inhibitors |
| SE0400585A SE0400585D0 (sv) | 2004-03-09 | 2004-03-09 | NNRTI Antivirals |
| PCT/SE2004/002034 WO2005066131A1 (en) | 2004-01-08 | 2004-12-30 | Non-nucleotide reverse transcriptase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1101400A1 true HK1101400A1 (en) | 2007-10-18 |
Family
ID=34752289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK07109407.1A HK1101400A1 (en) | 2004-01-08 | 2007-08-29 | Non-nucleotide reverse transcriptase inhibitors |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7915295B2 (es) |
| EP (1) | EP1701942B1 (es) |
| JP (1) | JP4762917B2 (es) |
| AT (1) | ATE451357T1 (es) |
| AU (1) | AU2004312284B2 (es) |
| BR (1) | BRPI0418306B8 (es) |
| CA (1) | CA2550187C (es) |
| DE (1) | DE602004024584D1 (es) |
| DK (1) | DK1701942T3 (es) |
| EA (1) | EA009700B1 (es) |
| ES (1) | ES2337794T3 (es) |
| HK (1) | HK1101400A1 (es) |
| IL (1) | IL176740A (es) |
| NZ (1) | NZ548367A (es) |
| SG (1) | SG149070A1 (es) |
| WO (1) | WO2005066131A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1534276B1 (en) * | 2002-09-05 | 2008-11-05 | Medivir AB | Non-nucleoside reverse transcriptase inhibitors |
| US7388008B2 (en) | 2004-08-02 | 2008-06-17 | Ambrilia Biopharma Inc. | Lysine based compounds |
| ES2539527T3 (es) * | 2005-04-27 | 2015-07-01 | Taimed Biologics, Inc. | Método para mejorar la farmacocinética de los inhibidores de las proteasas y de los precursores de los inhibidores de las proteasas |
| EP1971615B1 (en) | 2005-11-30 | 2014-01-01 | TaiMed Biologics, Inc. | Lysme-based prodrugs of aspartyl protease inhibitors and processes for their preparation |
| GB0608876D0 (en) * | 2006-05-05 | 2006-06-14 | Medivir Ab | Combination therapy |
| EP2021327B1 (en) * | 2006-05-15 | 2012-04-04 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| WO2008078200A2 (en) | 2006-09-21 | 2008-07-03 | Ambrilia Biopharma Inc. | Protease inhibitors |
| JP6636031B2 (ja) * | 2015-01-30 | 2020-01-29 | ジェネンテック， インコーポレイテッド | 治療用化合物およびその使用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200002058T2 (tr) * | 1998-01-16 | 2001-05-21 | Medivir Ab | Antiviraller |
| WO1999051613A1 (en) * | 1998-04-03 | 1999-10-14 | Medivir Ab | Prodrugs of phosphorous-containing pharmaceuticals |
| SE0100733D0 (sv) * | 2001-03-05 | 2001-03-05 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
| SE0102867D0 (sv) * | 2001-08-28 | 2001-08-28 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
| EP1534276B1 (en) * | 2002-09-05 | 2008-11-05 | Medivir AB | Non-nucleoside reverse transcriptase inhibitors |
-
2004
- 2004-12-30 AU AU2004312284A patent/AU2004312284B2/en not_active Ceased
- 2004-12-30 DK DK04809207.6T patent/DK1701942T3/da active
- 2004-12-30 JP JP2006549182A patent/JP4762917B2/ja not_active Expired - Fee Related
- 2004-12-30 ES ES04809207T patent/ES2337794T3/es active Active
- 2004-12-30 WO PCT/SE2004/002034 patent/WO2005066131A1/en active Application Filing
- 2004-12-30 SG SG200809639-8A patent/SG149070A1/en unknown
- 2004-12-30 NZ NZ548367A patent/NZ548367A/en not_active IP Right Cessation
- 2004-12-30 BR BRPI0418306A patent/BRPI0418306B8/pt not_active IP Right Cessation
- 2004-12-30 US US10/584,933 patent/US7915295B2/en not_active Expired - Fee Related
- 2004-12-30 AT AT04809207T patent/ATE451357T1/de not_active IP Right Cessation
- 2004-12-30 DE DE602004024584T patent/DE602004024584D1/de active Active
- 2004-12-30 EA EA200601289A patent/EA009700B1/ru not_active IP Right Cessation
- 2004-12-30 CA CA2550187A patent/CA2550187C/en not_active Expired - Fee Related
- 2004-12-30 EP EP04809207A patent/EP1701942B1/en active Active
-
2006
- 2006-07-06 IL IL176740A patent/IL176740A/en not_active IP Right Cessation
-
2007
- 2007-08-29 HK HK07109407.1A patent/HK1101400A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK1701942T3 (da) | 2010-04-06 |
| NZ548367A (en) | 2010-06-25 |
| EP1701942A1 (en) | 2006-09-20 |
| SG149070A1 (en) | 2009-01-29 |
| ES2337794T3 (es) | 2010-04-29 |
| AU2004312284A1 (en) | 2005-07-21 |
| BRPI0418306B1 (pt) | 2018-09-18 |
| IL176740A0 (en) | 2006-10-31 |
| DE602004024584D1 (de) | 2010-01-21 |
| JP4762917B2 (ja) | 2011-08-31 |
| BRPI0418306A (pt) | 2007-05-02 |
| BRPI0418306B8 (pt) | 2021-05-25 |
| EA009700B1 (ru) | 2008-02-28 |
| AU2004312284A2 (en) | 2005-07-21 |
| CA2550187C (en) | 2012-08-07 |
| AU2004312284B2 (en) | 2010-08-05 |
| JP2007519640A (ja) | 2007-07-19 |
| US20080070951A1 (en) | 2008-03-20 |
| WO2005066131A1 (en) | 2005-07-21 |
| EP1701942B1 (en) | 2009-12-09 |
| EA200601289A1 (ru) | 2006-12-29 |
| CA2550187A1 (en) | 2005-07-21 |
| ATE451357T1 (de) | 2009-12-15 |
| IL176740A (en) | 2011-09-27 |
| US7915295B2 (en) | 2011-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1101400A1 (en) | Non-nucleotide reverse transcriptase inhibitors | |
| EA200602060A1 (ru) | Производные пирролидин-2-она и пиперидин-2-она, используемые в качестве ингибиторов 11-бета-гидроксистероид-дегидрогеназы | |
| TW200621759A (en) | Novel aminopyridine derivatives having aurora A selective inhibitory action | |
| NZ596615A (en) | Substituted isoquinoline derivative | |
| TW200608972A (en) | Aryl-pyridine derivatives | |
| WO2006048330A8 (en) | 11βετα-hsd1 inhibitors | |
| HUP0400699A2 (hu) | Fenetanolaminszármazékok, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyszerkészítmények | |
| MX2008002152A (es) | Formulacion de bis(tio-hidrazida amida. | |
| CY1111310T1 (el) | Ενωσεις για την αγωγη μεταβολικων διαταραχων | |
| ECSP066548A (es) | 4-anilino-3-quinolincarbonitrilos para el tratamiento de leucemia mielogena cronica | |
| DK0409406T3 (da) | Arylsubstituerede aminderivater, der er anvendelige ved cancerterapi | |
| JP2010527915A5 (es) | ||
| MX2012006789A (es) | Derivados de etinilo. | |
| WO2009007536A3 (fr) | Dérivés de 7 -alkynyl-1,8-naphthyridones, leur préparation et leur application en thérapeutique | |
| ATE482199T1 (de) | Menthancarbonsäureamidderivate mit kühlenden eigenschaften | |
| WO2008078445A1 (ja) | 重合性化合物及び重合性組成物 | |
| MXPA05008706A (es) | 4-[(2, 4- dicloro-5 -metoxifenil) amino]-6 -alcoxi -3- quinolincarbonitrilos para tratamiento de lesiones isquemicas. | |
| TW200619201A (en) | Process for the preparation of pyrazoles | |
| MY140666A (en) | Biotinylated hexadecasaccharides, preparation and use thereof | |
| MX2022010673A (es) | Nuevos compuestos macrociclicos, un proceso para su preparacion y composiciones farmaceuticas que los contienen. | |
| CO5170535A1 (es) | Derivados de n-[2-(4-aminofenil)etil]2,3-dihidro-1,4- benzodioxin-2-metanamina, su preparacion y su aplciacion en terapeutica | |
| RS50580B (sr) | Novi inhibitori enzima zavisnih od folne kiseline | |
| SE0400021D0 (sv) | Non-nucleoside reverse transcriptase inhibitors | |
| HK1104555A1 (en) | 4 Ä(2,4-dichloro-5-methoxyphenyl)aminoÜ-6-alkoxy-7-ethynyl-3-quinolinecarbonitriles for the treatment of ischemic injury | |
| WO2006087571A3 (en) | Aromachemicals |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20171230 |