HK1089359A1 - Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections - Google Patents

Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections

Info

Publication number
HK1089359A1
HK1089359A1 HK06109627.6A HK06109627A HK1089359A1 HK 1089359 A1 HK1089359 A1 HK 1089359A1 HK 06109627 A HK06109627 A HK 06109627A HK 1089359 A1 HK1089359 A1 HK 1089359A1
Authority
HK
Hong Kong
Prior art keywords
prevention
treatment
bacterial infections
aztreonam lysinate
pulmonary bacterial
Prior art date
Application number
HK06109627.6A
Other languages
English (en)
Inventor
Alan Bruce Montgomery
Frank-Christophe Lintz
Manfred Keller
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34083679&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1089359(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/613,639 external-priority patent/US7214364B2/en
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of HK1089359A1 publication Critical patent/HK1089359A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK06109627.6A 2003-07-03 2006-08-29 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections HK1089359A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/613,639 US7214364B2 (en) 2000-12-27 2003-07-03 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
US10/882,985 US7138419B2 (en) 2000-12-27 2004-06-30 Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
PCT/US2004/021517 WO2005007132A1 (en) 2003-07-03 2004-07-01 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections

Publications (1)

Publication Number Publication Date
HK1089359A1 true HK1089359A1 (en) 2006-12-01

Family

ID=34083679

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06109627.6A HK1089359A1 (en) 2003-07-03 2006-08-29 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections

Country Status (14)

Country Link
US (1) US7138419B2 (pt)
EP (3) EP2452672A3 (pt)
JP (1) JP2007527398A (pt)
BR (1) BRPI0411949A (pt)
CA (1) CA2530774C (pt)
CY (2) CY1114621T1 (pt)
DK (2) DK2158901T3 (pt)
ES (2) ES2655036T3 (pt)
HK (1) HK1089359A1 (pt)
HU (2) HUE035150T2 (pt)
PL (2) PL1641436T5 (pt)
PT (2) PT1641436E (pt)
SI (2) SI1641436T2 (pt)
WO (1) WO2005007132A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214364B2 (en) * 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
PT2301524E (pt) * 2000-12-27 2013-07-10 Gilead Sciences Inc Aztreonam inalável sem arginina para tratamento e prevenção de infecções bacterianas pulmonares
US7138419B2 (en) † 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
ES2351651B2 (es) * 2003-07-02 2011-09-28 Gilead Sciences Inc. Método para la determinación de impurezas en una sal de lisina de aztreonám amorfa.
CA2733145C (en) * 2003-07-02 2012-06-19 Corus Pharma, Inc. Aztreonam l-lysine and method of determining impurities therein
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
US7973029B2 (en) * 2007-10-01 2011-07-05 Gilead Sciences, Inc. Inhaled aztreonam lysine for the treatment of deficits in health-related quality-of-life in lung diseases
CN101912356B (zh) * 2010-08-02 2012-01-11 王明 一种氨曲南/精氨酸药物组合物脂微球注射剂
EP3789031B1 (en) * 2010-09-17 2023-08-02 Technophage, Investigação e Desenvolvimento em Biotecnologia, SA Antibacterial phage, phage peptides and methods of use thereof
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10092552B2 (en) * 2011-01-31 2018-10-09 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
JP6426696B2 (ja) * 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
CN104784159A (zh) * 2015-04-15 2015-07-22 苏州惠仁生物科技有限公司 氨曲南粉雾剂的制备方法
CN107805618B (zh) * 2017-12-03 2021-04-06 李峰 一种改造盐碱地耕种性的微生物菌剂及其制备方法
CN110857474B (zh) * 2018-08-24 2023-04-18 武汉远大弘元股份有限公司 L-半胱氨酸盐酸盐一水合物的处理方法
WO2020174365A1 (en) * 2019-02-28 2020-09-03 Exorao Life Science S.R.L. Sterile aztreonam package
JPWO2020261619A1 (pt) * 2019-06-26 2020-12-30

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
US9126A (en) * 1852-07-13 Marcus r
US3984403A (en) † 1972-06-30 1976-10-05 Takeda Chemical Industries, Ltd. Arginine and lysine salts of acid cephalosporins
US4775670A (en) 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
WO1982001873A1 (en) 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
US4673739A (en) 1980-12-05 1987-06-16 Takeda Chemical Industries, Ltd. 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
US4572801A (en) 1981-04-30 1986-02-25 Takeda Chemical Industries, Ltd. 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
US4946838A (en) 1981-07-13 1990-08-07 E. R. Squibb & Sons, Inc. Crystalline anhydrous aztreonam
US4826973A (en) 1984-07-20 1989-05-02 E. R. Squibb & Sons, Inc. Delta form of aztreonam and preparation thereof
US4610824A (en) 1984-10-09 1986-09-09 E. R. Squibb & Sons, Inc. Hydrazide derivatives of monocyclic beta-lactam antibiotics
US4888998A (en) 1986-07-11 1989-12-26 Beckman Instruments, Inc. Sample handling system
CA1339136C (en) 1987-07-01 1997-07-29 Sailesh Amilal Varia Amorphous form of aztreonam
ATE219684T1 (de) 1994-01-14 2002-07-15 Xoma Technology Ltd Anti gram positive bakterielle verfahren und mittel
US5875776A (en) 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US5994340A (en) 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors
HU229310B1 (en) 1999-10-29 2013-10-28 Nektar Therapeutics Dry powder compositions having improved dispersivity
PT2301524E (pt) * 2000-12-27 2013-07-10 Gilead Sciences Inc Aztreonam inalável sem arginina para tratamento e prevenção de infecções bacterianas pulmonares
US7138419B2 (en) † 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
WO2003035030A1 (en) * 2001-10-24 2003-05-01 Pari Gmbh Kit for the preparation of a pharmaceutical composition
WO2003075889A1 (en) 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
EP1417958A1 (en) * 2002-11-08 2004-05-12 Pari GmbH Wet granulation process
AU2002356646A1 (en) * 2002-12-11 2004-06-30 Pari Gmbh Pharmaceutical compositions for the pulmonary delivery of aztreonam
CA2733145C (en) * 2003-07-02 2012-06-19 Corus Pharma, Inc. Aztreonam l-lysine and method of determining impurities therein

Also Published As

Publication number Publication date
SI2158901T1 (en) 2018-02-28
PT1641436E (pt) 2013-11-07
US20050063912A1 (en) 2005-03-24
EP2452672A2 (en) 2012-05-16
EP2158901A3 (en) 2010-03-17
SI1641436T1 (sl) 2013-12-31
HUS1800012I1 (hu) 2018-03-28
EP1641436A1 (en) 2006-04-05
CY1114621T1 (el) 2016-10-05
US7138419B2 (en) 2006-11-21
WO2005007132A1 (en) 2005-01-27
DK2158901T3 (en) 2018-01-15
EP1641436B1 (en) 2013-09-04
PL2158901T3 (pl) 2018-05-30
EP2158901A2 (en) 2010-03-03
ES2428030T3 (es) 2013-11-05
EP2452672A3 (en) 2013-11-06
PT2158901T (pt) 2018-01-15
PL1641436T5 (pl) 2017-10-31
DK1641436T4 (en) 2017-07-17
DK1641436T3 (da) 2013-09-30
PL1641436T3 (pl) 2014-02-28
CA2530774C (en) 2011-10-18
JP2007527398A (ja) 2007-09-27
SI1641436T2 (sl) 2017-08-31
CA2530774A1 (en) 2005-01-27
CY1119753T1 (el) 2018-06-27
EP1641436B2 (en) 2017-05-10
ES2428030T5 (es) 2017-07-25
ES2655036T3 (es) 2018-02-16
HUE035150T2 (en) 2018-05-02
BRPI0411949A (pt) 2006-08-29
EP2158901B1 (en) 2017-10-18

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Legal Events

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AM46 Amendment of patent specifications after grant under section 46 of the patents ordinance
PE Patent expired

Effective date: 20240630