HK1087338A1 - USE OF AN AGENT THAT STABILIZES HIFa FOR PREPARATION OF MEDICAMENT FOR REGULATING FAT METABOLISM - Google Patents

USE OF AN AGENT THAT STABILIZES HIFa FOR PREPARATION OF MEDICAMENT FOR REGULATING FAT METABOLISM

Info

Publication number
HK1087338A1
HK1087338A1 HK06107698.4A HK06107698A HK1087338A1 HK 1087338 A1 HK1087338 A1 HK 1087338A1 HK 06107698 A HK06107698 A HK 06107698A HK 1087338 A1 HK1087338 A1 HK 1087338A1
Authority
HK
Hong Kong
Prior art keywords
medicament
agent
preparation
fat metabolism
regulating fat
Prior art date
Application number
HK06107698.4A
Other languages
English (en)
Inventor
Patrick D Fourney
Volkmar Guenzler-Pukall
Stephen J Klaus
Al Y Lin
Thomas B Neff
Todd W Seeley
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of HK1087338A1 publication Critical patent/HK1087338A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
HK06107698.4A 2002-12-06 2006-07-10 USE OF AN AGENT THAT STABILIZES HIFa FOR PREPARATION OF MEDICAMENT FOR REGULATING FAT METABOLISM HK1087338A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43135102P 2002-12-06 2002-12-06
US47672603P 2003-06-06 2003-06-06
US47633103P 2003-06-06 2003-06-06
US10/729,167 US7618940B2 (en) 2002-12-06 2003-12-04 Fat regulation
PCT/US2003/038690 WO2004052285A2 (en) 2002-12-06 2003-12-05 Fat regulation

Publications (1)

Publication Number Publication Date
HK1087338A1 true HK1087338A1 (en) 2006-10-13

Family

ID=32512564

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06107698.4A HK1087338A1 (en) 2002-12-06 2006-07-10 USE OF AN AGENT THAT STABILIZES HIFa FOR PREPARATION OF MEDICAMENT FOR REGULATING FAT METABOLISM

Country Status (9)

Country Link
US (2) US7618940B2 (xx)
EP (1) EP1578431A4 (xx)
JP (1) JP2006514113A (xx)
AU (1) AU2003298926C1 (xx)
CA (1) CA2506159C (xx)
HK (1) HK1087338A1 (xx)
IL (1) IL168323A (xx)
NO (1) NO20053116L (xx)
WO (1) WO2004052285A2 (xx)

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US8124582B2 (en) * 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
PL1644336T3 (pl) * 2003-06-06 2011-07-29 Fibrogen Inc Związki heteroarylowe zawierające azot i ich zastosowanie w zwiększaniu poziomu endogennej erytropoetyny
MX2008009581A (es) 2006-01-27 2009-01-07 Fibrogen Inc Compuestos de cianoisoquinolina que estabilizan el factor inducible hipoxia (fih).
WO2007101204A1 (en) * 2006-02-27 2007-09-07 Alcon Research, Ltd. Method of treating glaucoma
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
MX2008012734A (es) * 2006-04-04 2009-01-29 Fibrogen Inc Compuestos pirrolo- y tiazolo-piridina como moduladores del factor inducible de hipoxia (hif).
US20080050740A1 (en) * 2006-06-23 2008-02-28 Cassidy Pamela M Nutritional and Exercise Plan Based On A Person's Individual Genetic APO E Genotype
EP3026044B8 (en) * 2006-06-26 2018-12-19 Akebia Therapeutics, Inc. Prolyl hydroxylase inhibitors and methods of use
WO2008076427A2 (en) * 2006-12-18 2008-06-26 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
EP2097416B1 (en) * 2006-12-18 2012-09-12 Amgen, Inc Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
US7569726B2 (en) * 2007-04-18 2009-08-04 Amgen Inc. Indanone derivatives that inhibit prolyl hydroxylase
JP2010524942A (ja) * 2007-04-18 2010-07-22 アムジエン・インコーポレーテツド プロリルヒドロキシラーゼを阻害するキノロン及びアザキノロン
AU2008248165B2 (en) * 2007-05-04 2011-12-08 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
EP2150251B9 (en) * 2007-05-04 2013-02-27 Amgen, Inc Thienopyridine and thiazolopyridine derivatives that inhibit prolyl hydroxylase activity
EP2227475B1 (en) * 2007-12-03 2014-02-19 Fibrogen, Inc. Isoxazolopyridine derivatives for use in the treatment of hif-mediated conditions
WO2009089547A1 (en) * 2008-01-11 2009-07-16 Fibrogen, Inc. Isothiazole-pyridine derivatives as modulators of hif (hypoxia inducible factor) activity
US8324405B2 (en) 2008-02-05 2012-12-04 Fibrogen, Inc. Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors
CN102076680B (zh) 2008-04-28 2016-03-02 詹森药业有限公司 作为脯氨酰羟化酶抑制剂的苯并咪唑
EP2334682B1 (en) * 2008-08-20 2017-10-04 Fibrogen, Inc. Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators
US8927591B2 (en) 2008-11-14 2015-01-06 Fibrogen, Inc. Thiochromene derivatives as HIF hydroxylase inhibitors
US8937078B2 (en) 2009-02-10 2015-01-20 Janssen Pharmaceutica Nv Quinazolinones as prolyl hydroxylase inhibitors
CN103068821B (zh) 2010-08-13 2015-02-25 詹森药业有限公司 作为脯氨酰羟化酶抑制剂的4-氨基喹唑啉-2-基-1-吡唑-4-羧酸化合物
US8921389B2 (en) 2011-02-02 2014-12-30 Fibrogen, Inc. Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase
JPWO2012105630A1 (ja) * 2011-02-03 2014-07-03 国立大学法人広島大学 脂質代謝関連疾患の検査方法、ならびに脂質代謝関連疾患の予防および／または治療剤の評価方法
GB201102659D0 (en) 2011-02-15 2011-03-30 Isis Innovation Assay
NO2686520T3 (xx) 2011-06-06 2018-03-17
WO2012170439A1 (en) 2011-06-06 2012-12-13 The Ohio State University Methods for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
GB201113101D0 (en) 2011-07-28 2011-09-14 Isis Innovation Assay
HUE052128T2 (hu) 2011-10-25 2021-04-28 Janssen Pharmaceutica Nv Eljárás az 1-(5,6-diklór-1H-benzo[d]imidazol-2-il)-1H-pirazol-4-karbonsav meglumin sója kristályainak elõállítására
US9409892B2 (en) 2012-03-09 2016-08-09 Fibrogen, Inc. 4-hydroxy-isoquinoline compounds as HIF hydroxylase inhibitors
CN104427980A (zh) * 2012-03-09 2015-03-18 菲布罗根有限公司 高胆固醇的治疗
ES2631655T3 (es) * 2012-07-16 2017-09-01 Fibrogen, Inc. Procedimiento para fabricar compuestos de isoquinolina
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
SI3470397T1 (sl) 2012-07-16 2022-07-29 Fibrogen, Inc. Kristalinične oblike zaviralca prolil hidroksilaze
KR102233081B1 (ko) 2013-01-24 2021-03-29 피브로겐, 인크. 〔[1-시아노-5-(4-클로로페녹시)-4-하이드록시-아이소퀴놀린-3-카보닐]-아미노〕-아세트산의 결정 형태
DK3003284T3 (da) * 2013-06-06 2020-03-30 Fibrogen Inc Farmaceutiske formuleringer af en hif-hydroxylase-inhibitor
CN114404414A (zh) 2013-06-13 2022-04-29 阿克比治疗有限公司 用于治疗贫血症的组合物和方法
AR099354A1 (es) 2013-11-15 2016-07-20 Akebia Therapeutics Inc Formas sólidas de ácido {[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino}acético, composiciones, y sus usos
WO2016118858A1 (en) 2015-01-23 2016-07-28 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
BR112017021097B1 (pt) 2015-04-01 2024-01-02 Akebia Therapeutics, Inc Formulação de dosagem oral e seu uso
WO2016164593A1 (en) * 2015-04-07 2016-10-13 President And Fellows Of Harvard College Compositions and methods for modulating hydroxylation of acc2 by phd3
CN109180580B (zh) 2016-02-28 2021-01-12 深圳市塔吉瑞生物医药有限公司 一种取代的杂芳基化合物及包含该化合物的组合物及其用途
AU2017406103B2 (en) * 2017-03-29 2023-12-14 Emerald Health Pharmaceuticals, Inc. Cannabidiol derivatives as inhibitors of the HIF prolyl hydroxylases activity
TWI822776B (zh) 2018-05-09 2023-11-21 美商阿克比治療有限公司 用於製備2-[[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基]乙酸之方法
CN113164334A (zh) * 2018-10-12 2021-07-23 米拉基创新智库有限责任公司 用于减脂的低温溶液
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

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Also Published As

Publication number Publication date
AU2003298926C1 (en) 2010-02-04
US7618940B2 (en) 2009-11-17
US8202834B2 (en) 2012-06-19
AU2003298926A1 (en) 2004-06-30
CA2506159C (en) 2011-05-24
JP2006514113A (ja) 2006-04-27
AU2003298926B2 (en) 2009-09-03
WO2004052285A2 (en) 2004-06-24
US20040235082A1 (en) 2004-11-25
EP1578431A4 (en) 2008-04-23
NO20053116D0 (no) 2005-06-24
CA2506159A1 (en) 2004-06-24
NO20053116L (no) 2005-09-05
IL168323A (en) 2011-07-31
EP1578431A2 (en) 2005-09-28
WO2004052285A3 (en) 2004-09-02
US20100168152A1 (en) 2010-07-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20131205