HK1084032A1 - Combination therapy of zd6474 with 5-fu and/or cpt-11 - Google Patents

Combination therapy of zd6474 with 5-fu and/or cpt-11

Info

Publication number
HK1084032A1
HK1084032A1 HK06104405.5A HK06104405A HK1084032A1 HK 1084032 A1 HK1084032 A1 HK 1084032A1 HK 06104405 A HK06104405 A HK 06104405A HK 1084032 A1 HK1084032 A1 HK 1084032A1
Authority
HK
Hong Kong
Prior art keywords
cpt
combination
combination therapy
cancer
antiangiogenic
Prior art date
Application number
HK06104405.5A
Other languages
English (en)
Inventor
Stephen Robert Wedge
Anderson Joseph Ryan
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0303289A external-priority patent/GB0303289D0/en
Priority claimed from GB0314100A external-priority patent/GB0314100D0/en
Priority claimed from GB0316184A external-priority patent/GB0316184D0/en
Priority claimed from GB0318311A external-priority patent/GB0318311D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1084032A1 publication Critical patent/HK1084032A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK06104405.5A 2003-02-13 2006-04-11 Combination therapy of zd6474 with 5-fu and/or cpt-11 HK1084032A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0303289A GB0303289D0 (en) 2003-02-13 2003-02-13 Combination therapy
GB0314100A GB0314100D0 (en) 2003-06-18 2003-06-18 Combination therapy
GB0316184A GB0316184D0 (en) 2003-07-10 2003-07-10 Combination therapy
GB0318311A GB0318311D0 (en) 2003-08-05 2003-08-05 Combination therapy
PCT/GB2004/000550 WO2004071397A2 (en) 2003-02-13 2004-02-11 Combination therapy of zd6474 with 5-fu or/and cpt-11

Publications (1)

Publication Number Publication Date
HK1084032A1 true HK1084032A1 (en) 2006-07-21

Family

ID=32872851

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06104405.5A HK1084032A1 (en) 2003-02-13 2006-04-11 Combination therapy of zd6474 with 5-fu and/or cpt-11

Country Status (18)

Country Link
US (4) US20060142316A1 (xx)
EP (1) EP1592423B1 (xx)
JP (3) JP2006517575A (xx)
KR (2) KR20050100683A (xx)
AT (1) ATE506062T1 (xx)
AU (1) AU2004212255B2 (xx)
CA (1) CA2514227C (xx)
CY (1) CY1111565T1 (xx)
DE (1) DE602004032310D1 (xx)
DK (1) DK1592423T3 (xx)
HK (1) HK1084032A1 (xx)
IL (1) IL169702A (xx)
MX (1) MXPA05008583A (xx)
NO (1) NO331486B1 (xx)
NZ (1) NZ541297A (xx)
PT (1) PT1592423E (xx)
SI (1) SI1592423T1 (xx)
WO (1) WO2004071397A2 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE330954T1 (de) 1999-11-05 2006-07-15 Astrazeneca Ab Quinazolin-derivate als vegf-hemmer
GB0008269D0 (en) 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
GB0126879D0 (en) * 2001-11-08 2002-01-02 Astrazeneca Ab Combination therapy
GB0218526D0 (en) * 2002-08-09 2002-09-18 Astrazeneca Ab Combination therapy
GB0223380D0 (en) * 2002-10-09 2002-11-13 Astrazeneca Ab Combination therapy
CA2503371C (en) 2002-11-04 2011-01-11 Astrazeneca Ab Quinazoline derivatives as src tyrosine kinase inhibitors
WO2004071397A2 (en) * 2003-02-13 2004-08-26 Astrazeneca Ab Combination therapy of zd6474 with 5-fu or/and cpt-11
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
DE602004028834D1 (de) * 2003-07-10 2010-10-07 Astrazeneca Ab Verwendung des chinazolin-derivats zd6474 in kombination mit platinverbindungen und optional ionisierender strahlung bei der behandlung von erkrankungen im zusammenhang mit angiogenese und/oder erhöhter gefässpermeabilität
MXPA06014021A (es) * 2004-06-04 2007-02-08 Pfizer Prod Inc Procedimiento para tratar crecimiento celular anormal.
KR20070072543A (ko) * 2004-09-27 2007-07-04 아스트라제네카 아베 Ｚｄ6474 및 이마티닙을 포함하는 병합법
GB0424339D0 (en) * 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
GB0519879D0 (en) 2005-09-30 2005-11-09 Astrazeneca Ab Chemical process
ATE500832T1 (de) * 2005-12-22 2011-03-15 Astrazeneca Ab Kombination von zd6474 und pemetrexed
CN101553253A (zh) * 2006-09-29 2009-10-07 阿斯利康(瑞典)有限公司 用于癌症治疗的zd6474和贝伐单抗的组合

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE330954T1 (de) * 1999-11-05 2006-07-15 Astrazeneca Ab Quinazolin-derivate als vegf-hemmer
GB0008269D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
GB0126879D0 (en) * 2001-11-08 2002-01-02 Astrazeneca Ab Combination therapy
GB0218526D0 (en) * 2002-08-09 2002-09-18 Astrazeneca Ab Combination therapy
EP1534287A1 (en) * 2002-08-09 2005-06-01 Astrazeneca AB Combination of zd6474, an inhibitor of the vascular endothelial growth factor receptor, with radiotherapy in the treatment of cancer
GB0223380D0 (en) * 2002-10-09 2002-11-13 Astrazeneca Ab Combination therapy
WO2004071397A2 (en) * 2003-02-13 2004-08-26 Astrazeneca Ab Combination therapy of zd6474 with 5-fu or/and cpt-11
DE602004028834D1 (de) * 2003-07-10 2010-10-07 Astrazeneca Ab Verwendung des chinazolin-derivats zd6474 in kombination mit platinverbindungen und optional ionisierender strahlung bei der behandlung von erkrankungen im zusammenhang mit angiogenese und/oder erhöhter gefässpermeabilität
KR20070072543A (ko) * 2004-09-27 2007-07-04 아스트라제네카 아베 Ｚｄ6474 및 이마티닙을 포함하는 병합법
GB0424339D0 (en) * 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
JP4834985B2 (ja) * 2004-12-10 2011-12-14 日産自動車株式会社 組電池の容量調整装置
ATE500832T1 (de) * 2005-12-22 2011-03-15 Astrazeneca Ab Kombination von zd6474 und pemetrexed
CN101553253A (zh) * 2006-09-29 2009-10-07 阿斯利康(瑞典)有限公司 用于癌症治疗的zd6474和贝伐单抗的组合

Also Published As

Publication number Publication date
CA2514227A1 (en) 2004-08-26
WO2004071397A2 (en) 2004-08-26
EP1592423A2 (en) 2005-11-09
IL169702A (en) 2014-05-28
DE602004032310D1 (de) 2011-06-01
NO331486B1 (no) 2012-01-16
JP2011016853A (ja) 2011-01-27
AU2004212255B2 (en) 2007-07-05
US20060142316A1 (en) 2006-06-29
JP2014065750A (ja) 2014-04-17
SI1592423T1 (sl) 2011-07-29
US20110086870A1 (en) 2011-04-14
MXPA05008583A (es) 2005-11-04
JP5563950B2 (ja) 2014-07-30
KR20110006699A (ko) 2011-01-20
WO2004071397A3 (en) 2004-10-14
NO20053649L (no) 2005-09-12
KR20050100683A (ko) 2005-10-19
US20100130520A1 (en) 2010-05-27
JP2006517575A (ja) 2006-07-27
AU2004212255A1 (en) 2004-08-26
ATE506062T1 (de) 2011-05-15
NZ541297A (en) 2008-03-28
IL169702A0 (en) 2007-07-04
DK1592423T3 (da) 2011-06-27
NO20053649D0 (no) 2005-07-27
EP1592423B1 (en) 2011-04-20
CY1111565T1 (el) 2015-10-07
CA2514227C (en) 2011-08-09
US20120252826A1 (en) 2012-10-04
PT1592423E (pt) 2011-06-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150211