HK1083192A1 - West nile virus vaccine - Google Patents
West nile virus vaccineInfo
- Publication number
- HK1083192A1 HK1083192A1 HK06103120.1A HK06103120A HK1083192A1 HK 1083192 A1 HK1083192 A1 HK 1083192A1 HK 06103120 A HK06103120 A HK 06103120A HK 1083192 A1 HK1083192 A1 HK 1083192A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- west nile
- nile virus
- virus vaccine
- vaccines
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42659202P | 2002-11-15 | 2002-11-15 | |
PCT/US2003/036623 WO2004045529A2 (en) | 2002-11-15 | 2003-11-13 | West nile virus vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1083192A1 true HK1083192A1 (en) | 2006-06-30 |
Family
ID=32326380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06103120.1A HK1083192A1 (en) | 2002-11-15 | 2006-03-10 | West nile virus vaccine |
Country Status (16)
Country | Link |
---|---|
US (2) | US7507415B2 (ko) |
EP (1) | EP1575979B1 (ko) |
JP (1) | JP4683926B2 (ko) |
KR (1) | KR101150584B1 (ko) |
AT (1) | ATE452900T1 (ko) |
AU (1) | AU2003290985B2 (ko) |
BR (1) | BRPI0316346B1 (ko) |
CA (1) | CA2505942C (ko) |
DE (1) | DE60330708D1 (ko) |
ES (1) | ES2337893T3 (ko) |
HK (1) | HK1083192A1 (ko) |
IL (2) | IL168584A (ko) |
MX (1) | MXPA05005140A (ko) |
RU (1) | RU2376374C2 (ko) |
WO (1) | WO2004045529A2 (ko) |
ZA (1) | ZA200503871B (ko) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6962708B1 (en) * | 1997-02-28 | 2005-11-08 | Acambis, Inc. | Chimeric flavivirus vaccines |
CN1551782A (zh) * | 2001-06-01 | 2004-12-01 | ��������ķ������ | 嵌合黄病毒载体 |
US20050002968A1 (en) * | 2002-01-15 | 2005-01-06 | Monath Thomas P. | Flavivirus vaccines |
BR122018075730B1 (pt) | 2002-01-15 | 2022-04-19 | Acambis, Inc | Flavivírus na preparação de uma composição de vacina e composição de vacina |
AU2003239932A1 (en) * | 2002-05-31 | 2003-12-19 | Acambis, Inc. | Tetravalent dengue vaccines |
US7785799B2 (en) * | 2002-08-16 | 2010-08-31 | The Board Of Regents Of The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain III antigens |
EP1575979B1 (en) | 2002-11-15 | 2009-12-23 | Sanofi Pasteur Biologics Co. | West nile virus vaccine |
WO2006029300A2 (en) | 2004-09-09 | 2006-03-16 | Research Development Foundation | Flavivirus variants having phenotypic variation and immunogenic compositions thereof |
WO2006044857A2 (en) | 2004-10-20 | 2006-04-27 | Acambis Inc. | Vaccines against japanese encephalitis virus and west nile virus |
AU2005320001B2 (en) | 2004-12-24 | 2011-05-19 | The Research Foundation For Microbial Diseases Of Osaka University | Attenuated chimeric flavivirus bearing attenuated Japanese encephalitis virus gene as backbone |
EP1874346B1 (en) * | 2005-04-24 | 2014-06-25 | Sanofi Pasteur Biologics, LLC | Recombinant flavivirus vaccines |
AU2013204985B2 (en) * | 2005-04-24 | 2016-01-28 | Sanofi Pasteur Biologics, Llc | Recombinant flavivirus vaccines |
US8017754B2 (en) * | 2005-07-22 | 2011-09-13 | Research Development Foundation | Attenuated virus strains and uses thereof |
RU2541784C2 (ru) | 2006-11-07 | 2015-02-20 | Санофи Пастер Байолоджикс Ко. | Лиофилизированная композиция для индукции иммунного ответа на флавивирус, композиция и способ для ее получения |
AU2007353773A1 (en) * | 2006-12-22 | 2008-11-27 | Dow Agrosciences Llc | Plant-made West Nile virus (WNV) vaccines, vectors and plant codon optimized sequences |
MX2010008799A (es) | 2008-03-05 | 2010-09-07 | Sanofi Pasteur | Proceso para estabilizar una composicion de vacuna que contiene adyuvante. |
EP2143440A1 (fr) | 2008-07-09 | 2010-01-13 | Sanofi Pasteur | Agent stabilisant et composition vaccinale comprenant un ou plusieurs flavivirus vivants atténués |
CA2735164C (en) * | 2008-08-29 | 2021-08-31 | Boehringer Ingelheim Vetmedica, Inc. | West nile virus vaccine |
WO2010085358A2 (en) * | 2009-01-23 | 2010-07-29 | The Board Of Regents Of The University Of Texas System | Flaviviruses expressing the prm, e, and ns1 proteins of other flaviviruses and uses thereof |
JP6057460B2 (ja) * | 2009-08-31 | 2017-01-11 | ジェン−プローブ・インコーポレーテッド | デングウイルスアッセイ |
BR112012024224A2 (pt) * | 2010-03-24 | 2016-11-29 | Arbovax Inc | mutações da faixa de hospedeiro de flavivírus e seu uso. |
US8889148B2 (en) | 2010-07-01 | 2014-11-18 | Research Development Foundation | Flavivirus host-range mutations and uses thereof |
ES2842595T3 (es) | 2011-03-14 | 2021-07-14 | Boehringer Ingelheim Animal Health Usa Inc | Vacuna contra la rinitis equina |
WO2013138670A1 (en) * | 2012-03-15 | 2013-09-19 | Icahn School Of Medicine At Mount Sinai | Yellow fever virus ns5 mutants as flavivirus vaccine candidates |
US9267114B2 (en) * | 2012-11-07 | 2016-02-23 | Southern Research Institute | Flavivirus envelope protein mutations affecting virion disassembly |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184024B1 (en) | 1988-07-14 | 2001-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric and/or growth-restricted flaviviruses |
ATE310824T1 (de) | 1991-09-19 | 2005-12-15 | Chimäre und/oder wachstumsgehemmte flaviviren | |
US6136561A (en) * | 1995-05-24 | 2000-10-24 | Hawaii Biotechnology Group, Inc. | Methods of preparing carboxy-terminally truncated recombinant flavivirus envelope glycoproteins employing drosophila melanogaster expression systems |
US6962708B1 (en) | 1997-02-28 | 2005-11-08 | Acambis, Inc. | Chimeric flavivirus vaccines |
HU228705B1 (en) | 1997-02-28 | 2013-05-28 | Univ St Louis | Chimeric flavivirus vaccines |
BRPI9701774B8 (pt) | 1997-04-11 | 2015-09-29 | Fundação Oswaldo Cruz Fiocruz | cdna mutante e infeccioso do vírus da febre amarela, constructo de dna, vírus recombinante de febre amarela e vacina para humanos contra infecções de febre amarela. |
US6416763B1 (en) | 1998-08-28 | 2002-07-09 | Hawaii Biotechnology Group, Inc. | Recombinant nonstructural protein subunit vaccine against flaviviral infection |
WO2001039802A1 (en) | 1999-12-01 | 2001-06-07 | Oravax, Inc. | Chimeric flavivirus vaccines |
GB2372991B (en) | 2001-03-09 | 2004-11-17 | Fiocruz Fundacao Oswaldo Cruz | Flavivirus expression vector |
CN1551782A (zh) | 2001-06-01 | 2004-12-01 | ��������ķ������ | 嵌合黄病毒载体 |
US6682883B1 (en) * | 2001-07-19 | 2004-01-27 | Acambis, Inc. | Diagnosis of flavivirus infection |
US6878372B2 (en) | 2001-10-19 | 2005-04-12 | Acambis Inc. | Methods of preventing and treating flavivirus infection in animals |
DE20120256U1 (de) * | 2001-12-14 | 2002-03-07 | Häfele GmbH & Co., 72202 Nagold | Beschlag |
BR122018075730B1 (pt) | 2002-01-15 | 2022-04-19 | Acambis, Inc | Flavivírus na preparação de uma composição de vacina e composição de vacina |
US20050002968A1 (en) | 2002-01-15 | 2005-01-06 | Monath Thomas P. | Flavivirus vaccines |
AU2003239932A1 (en) | 2002-05-31 | 2003-12-19 | Acambis, Inc. | Tetravalent dengue vaccines |
EP1575979B1 (en) * | 2002-11-15 | 2009-12-23 | Sanofi Pasteur Biologics Co. | West nile virus vaccine |
US7189403B2 (en) | 2003-06-30 | 2007-03-13 | Institut Pasteur | Attenuated flavivirus strains containing a mutated M-ectodomain and their applications |
WO2005040390A1 (fr) | 2003-07-21 | 2005-05-06 | Shanghai Tengen Biomedical Co., Ltd. | Vaccin recombine utilisant le virus de la fievre jaune comme vecteur |
WO2005049815A1 (en) | 2003-11-21 | 2005-06-02 | K.U.Leuven Research & Development | Flavivirus replication |
WO2006044857A2 (en) | 2004-10-20 | 2006-04-27 | Acambis Inc. | Vaccines against japanese encephalitis virus and west nile virus |
EP1874346B1 (en) | 2005-04-24 | 2014-06-25 | Sanofi Pasteur Biologics, LLC | Recombinant flavivirus vaccines |
BRPI0504945B8 (pt) | 2005-10-31 | 2022-08-02 | Fundacao Oswaldo Cruz | Método para a produção de flavivirus recombinante contendo sequências de nucleotídeos codificantes de uma proteína heteróloga, constructo de dna, flavivirus, e, composição vacinal para imunizar contra flavivirus e/ou outros patógenos. |
-
2003
- 2003-11-13 EP EP03783570A patent/EP1575979B1/en not_active Expired - Lifetime
- 2003-11-13 KR KR1020057008744A patent/KR101150584B1/ko not_active IP Right Cessation
- 2003-11-13 MX MXPA05005140A patent/MXPA05005140A/es active IP Right Grant
- 2003-11-13 WO PCT/US2003/036623 patent/WO2004045529A2/en active Application Filing
- 2003-11-13 ES ES03783570T patent/ES2337893T3/es not_active Expired - Lifetime
- 2003-11-13 DE DE60330708T patent/DE60330708D1/de not_active Expired - Lifetime
- 2003-11-13 JP JP2004553787A patent/JP4683926B2/ja not_active Expired - Fee Related
- 2003-11-13 RU RU2005118419/13A patent/RU2376374C2/ru not_active IP Right Cessation
- 2003-11-13 CA CA2505942A patent/CA2505942C/en not_active Expired - Fee Related
- 2003-11-13 AU AU2003290985A patent/AU2003290985B2/en not_active Ceased
- 2003-11-13 AT AT03783570T patent/ATE452900T1/de not_active IP Right Cessation
- 2003-11-13 BR BRPI0316346A patent/BRPI0316346B1/pt not_active IP Right Cessation
- 2003-11-17 US US10/715,868 patent/US7507415B2/en not_active Expired - Fee Related
-
2005
- 2005-05-13 ZA ZA200503871A patent/ZA200503871B/en unknown
- 2005-05-15 IL IL168584A patent/IL168584A/en active IP Right Grant
-
2006
- 2006-03-10 HK HK06103120.1A patent/HK1083192A1/xx not_active IP Right Cessation
-
2009
- 2009-03-23 US US12/409,120 patent/US8088391B2/en not_active Expired - Fee Related
- 2009-12-27 IL IL202978A patent/IL202978A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
AU2003290985A1 (en) | 2004-06-15 |
ATE452900T1 (de) | 2010-01-15 |
IL202978A0 (en) | 2011-08-01 |
EP1575979A4 (en) | 2006-06-21 |
KR101150584B1 (ko) | 2012-06-27 |
US20100086564A1 (en) | 2010-04-08 |
IL202978A (en) | 2013-11-28 |
WO2004045529A3 (en) | 2004-08-26 |
ZA200503871B (en) | 2006-08-30 |
IL168584A (en) | 2010-12-30 |
JP4683926B2 (ja) | 2011-05-18 |
US20070275015A9 (en) | 2007-11-29 |
RU2376374C2 (ru) | 2009-12-20 |
KR20050072143A (ko) | 2005-07-08 |
US7507415B2 (en) | 2009-03-24 |
CA2505942A1 (en) | 2004-06-03 |
RU2005118419A (ru) | 2006-01-20 |
WO2004045529A2 (en) | 2004-06-03 |
BR0316346A (pt) | 2005-09-27 |
BRPI0316346B1 (pt) | 2016-05-31 |
DE60330708D1 (de) | 2010-02-04 |
ES2337893T3 (es) | 2010-04-30 |
AU2003290985B2 (en) | 2010-04-01 |
JP2006506092A (ja) | 2006-02-23 |
CA2505942C (en) | 2012-03-13 |
US20050053624A1 (en) | 2005-03-10 |
EP1575979B1 (en) | 2009-12-23 |
EP1575979A2 (en) | 2005-09-21 |
US8088391B2 (en) | 2012-01-03 |
MXPA05005140A (es) | 2005-08-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20181116 |