HK1081880A1 - Alpha 2b or 2b/2c adrenoceptor agonists for the treatment of neurodegeneration - Google Patents
Alpha 2b or 2b/2c adrenoceptor agonists for the treatment of neurodegenerationInfo
- Publication number
- HK1081880A1 HK1081880A1 HK06104018.4A HK06104018A HK1081880A1 HK 1081880 A1 HK1081880 A1 HK 1081880A1 HK 06104018 A HK06104018 A HK 06104018A HK 1081880 A1 HK1081880 A1 HK 1081880A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- alpha
- neurodegeneration
- treatment
- adrenoceptor agonists
- disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41704902P | 2002-10-08 | 2002-10-08 | |
PCT/US2003/031809 WO2004032913A1 (en) | 2002-10-08 | 2003-10-07 | Alpha 2b 0r 2b/2c adrenoceptor agonists for the treatment of neurodegeneration |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1081880A1 true HK1081880A1 (en) | 2006-05-26 |
Family
ID=32093954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06104018.4A HK1081880A1 (en) | 2002-10-08 | 2006-03-31 | Alpha 2b or 2b/2c adrenoceptor agonists for the treatment of neurodegeneration |
Country Status (20)
Country | Link |
---|---|
US (1) | US20040138312A1 (xx) |
EP (1) | EP1549305B1 (xx) |
JP (2) | JP4724421B2 (xx) |
KR (1) | KR20050050124A (xx) |
CN (1) | CN100431536C (xx) |
AT (1) | ATE429216T1 (xx) |
AU (2) | AU2003282758A1 (xx) |
BR (1) | BR0314540A (xx) |
CA (1) | CA2501347A1 (xx) |
DE (1) | DE60327335D1 (xx) |
ES (1) | ES2322954T3 (xx) |
HK (1) | HK1081880A1 (xx) |
IL (1) | IL167849A (xx) |
MX (1) | MXPA05003664A (xx) |
NO (1) | NO20051663L (xx) |
NZ (1) | NZ539328A (xx) |
PL (1) | PL216373B1 (xx) |
RU (1) | RU2330649C2 (xx) |
WO (1) | WO2004032913A1 (xx) |
ZA (1) | ZA200502744B (xx) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2007206A4 (en) * | 2006-03-16 | 2010-12-08 | Yeda Res & Dev | METHOD AND COMPOSITION FOR THE PROTECTION OF NEURONAL TISSUE FROM DEGATES INDUCED BY HIGH LEVELS OF GLUTAMATE |
WO2009052075A2 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Method of treating motor disorders with alpha-2b adrenergic receptor agonists |
US20100216857A1 (en) * | 2007-10-18 | 2010-08-26 | Luhrs Lauren M B | Method of treating motor disorders with 4-(1-(2,3-dimethylphenyl)ethyl)-1h-imidazole-2(3h)-thione |
WO2009052073A2 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Method of treating sensorimotor disorders with alpha-2 adrenergic receptor agonists |
JP5705742B2 (ja) * | 2008-12-08 | 2015-04-22 | アラーガン インコーポレイテッドAllergan,Incorporated | アルファ2bまたはアルファ2bおよびアルファ2cアドレノセプターのサブタイプ選択性モジュレーターとしてのn‐(1‐フェニル‐2‐アリールエチル)‐4,5‐ジヒドロ‐3h‐ピロール‐2‐アミン化合物 |
EP4371554A2 (en) | 2016-12-31 | 2024-05-22 | BioXcel Therapeutics, Inc. | Use of sublingual dexmedetomidine for the treatment of agitation |
CN114983980A (zh) | 2018-06-27 | 2022-09-02 | 比奥克斯塞尔医疗股份有限公司 | 含右美托咪定的膜制剂及其制造方法 |
BR112022000992A2 (pt) | 2019-07-19 | 2022-06-14 | Arx Llc | Regimes de tratamento de dexmedetomidina não sedantes |
US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4029792A (en) * | 1972-02-29 | 1977-06-14 | Pfizer Inc. | (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents |
BE795970A (fr) * | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
US6194415B1 (en) * | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
US6329369B1 (en) * | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
US6841684B2 (en) * | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
EP1413576A3 (en) * | 1997-12-04 | 2004-09-01 | Allergan, Inc. | Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors |
US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
IL151530A0 (en) * | 2000-07-14 | 2003-04-10 | Allergan Sales Inc | Compositions containing alpha-2-adrenergic agonist components |
AU2002248284A1 (en) * | 2000-11-01 | 2002-08-06 | Allergan, Inc. | Compositions for treatment of ocular neovascularization |
US7091232B2 (en) * | 2002-05-21 | 2006-08-15 | Allergan, Inc. | 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds |
-
2003
- 2003-10-07 PL PL376346A patent/PL216373B1/pl unknown
- 2003-10-07 BR BR0314540-9A patent/BR0314540A/pt not_active Application Discontinuation
- 2003-10-07 AT AT03774642T patent/ATE429216T1/de not_active IP Right Cessation
- 2003-10-07 MX MXPA05003664A patent/MXPA05003664A/es active IP Right Grant
- 2003-10-07 WO PCT/US2003/031809 patent/WO2004032913A1/en active Application Filing
- 2003-10-07 DE DE60327335T patent/DE60327335D1/de not_active Expired - Lifetime
- 2003-10-07 RU RU2005114504/14A patent/RU2330649C2/ru not_active IP Right Cessation
- 2003-10-07 US US10/680,879 patent/US20040138312A1/en not_active Abandoned
- 2003-10-07 JP JP2004543495A patent/JP4724421B2/ja not_active Expired - Fee Related
- 2003-10-07 KR KR1020057006114A patent/KR20050050124A/ko active IP Right Grant
- 2003-10-07 AU AU2003282758A patent/AU2003282758A1/en not_active Abandoned
- 2003-10-07 NZ NZ539328A patent/NZ539328A/en not_active IP Right Cessation
- 2003-10-07 ES ES03774642T patent/ES2322954T3/es not_active Expired - Lifetime
- 2003-10-07 EP EP03774642A patent/EP1549305B1/en not_active Expired - Lifetime
- 2003-10-07 CN CNB200380101115XA patent/CN100431536C/zh not_active Expired - Fee Related
- 2003-10-07 CA CA002501347A patent/CA2501347A1/en not_active Abandoned
-
2005
- 2005-04-04 NO NO20051663A patent/NO20051663L/no unknown
- 2005-04-04 IL IL167849A patent/IL167849A/en active IP Right Grant
- 2005-04-05 ZA ZA200502744A patent/ZA200502744B/en unknown
-
2006
- 2006-03-31 HK HK06104018.4A patent/HK1081880A1/xx not_active IP Right Cessation
-
2009
- 2009-11-20 AU AU2009238370A patent/AU2009238370B2/en not_active Ceased
-
2010
- 2010-12-03 JP JP2010270724A patent/JP2011057700A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20040138312A1 (en) | 2004-07-15 |
BR0314540A (pt) | 2005-07-26 |
JP2006504739A (ja) | 2006-02-09 |
DE60327335D1 (de) | 2009-06-04 |
CA2501347A1 (en) | 2004-04-22 |
CN100431536C (zh) | 2008-11-12 |
PL376346A1 (en) | 2005-12-27 |
JP4724421B2 (ja) | 2011-07-13 |
AU2009238370B2 (en) | 2011-07-21 |
MXPA05003664A (es) | 2005-06-08 |
PL216373B1 (pl) | 2014-03-31 |
NZ539328A (en) | 2007-01-26 |
AU2003282758A1 (en) | 2004-05-04 |
AU2009238370A1 (en) | 2009-12-17 |
ATE429216T1 (de) | 2009-05-15 |
IL167849A (en) | 2011-04-28 |
CN1703213A (zh) | 2005-11-30 |
EP1549305B1 (en) | 2009-04-22 |
WO2004032913A1 (en) | 2004-04-22 |
ES2322954T3 (es) | 2009-07-02 |
NO20051663L (no) | 2005-05-31 |
RU2005114504A (ru) | 2005-10-27 |
ZA200502744B (en) | 2006-02-22 |
JP2011057700A (ja) | 2011-03-24 |
RU2330649C2 (ru) | 2008-08-10 |
EP1549305A1 (en) | 2005-07-06 |
KR20050050124A (ko) | 2005-05-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20151007 |