NO20051663L - Fremgangsmater for behandling av neurodegenerasjon - Google Patents
Fremgangsmater for behandling av neurodegenerasjonInfo
- Publication number
- NO20051663L NO20051663L NO20051663A NO20051663A NO20051663L NO 20051663 L NO20051663 L NO 20051663L NO 20051663 A NO20051663 A NO 20051663A NO 20051663 A NO20051663 A NO 20051663A NO 20051663 L NO20051663 L NO 20051663L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- treating neurodegeneration
- disease
- alpha
- treating
- Prior art date
Links
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 230000007850 degeneration Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 230000000979 retarding effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Det beskrives fremgangsmåter for forhindring eller retardering av degenereringen av neuroner. Det beskrives også fremgangsmåter for behandling av Aizheimers sykdom eller Parkinsons sykdom gjennom administreringen av selektive alfa 2B eller alfa 2B/2C reseptoragonister.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41704902P | 2002-10-08 | 2002-10-08 | |
| PCT/US2003/031809 WO2004032913A1 (en) | 2002-10-08 | 2003-10-07 | Alpha 2b 0r 2b/2c adrenoceptor agonists for the treatment of neurodegeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20051663L true NO20051663L (no) | 2005-05-31 |
Family
ID=32093954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20051663A NO20051663L (no) | 2002-10-08 | 2005-04-04 | Fremgangsmater for behandling av neurodegenerasjon |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20040138312A1 (no) |
| EP (1) | EP1549305B1 (no) |
| JP (2) | JP4724421B2 (no) |
| KR (1) | KR20050050124A (no) |
| CN (1) | CN100431536C (no) |
| AT (1) | ATE429216T1 (no) |
| AU (2) | AU2003282758A1 (no) |
| BR (1) | BR0314540A (no) |
| CA (1) | CA2501347A1 (no) |
| DE (1) | DE60327335D1 (no) |
| ES (1) | ES2322954T3 (no) |
| IL (1) | IL167849A (no) |
| MX (1) | MXPA05003664A (no) |
| NO (1) | NO20051663L (no) |
| NZ (1) | NZ539328A (no) |
| PL (1) | PL216373B1 (no) |
| RU (1) | RU2330649C2 (no) |
| WO (1) | WO2004032913A1 (no) |
| ZA (1) | ZA200502744B (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090304661A1 (en) * | 2006-03-16 | 2009-12-10 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Sceince | Method And Composition For Proctecting Neuronal Tissue From Damage Induced By Elevated Glutamate Levels |
| WO2009052073A2 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Method of treating sensorimotor disorders with alpha-2 adrenergic receptor agonists |
| WO2009052072A1 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Treating motor disorders with 4-(1-(2,3-dimethylphenyl)ethyl)-1h-imidazole-2(3h)-thione |
| US20110160265A1 (en) * | 2007-10-18 | 2011-06-30 | Luhrs Lauren M B | Method of treating motor disorders with alpha-2b adrenergic receptor agonists |
| CA2746295A1 (en) * | 2008-12-08 | 2010-07-08 | Allergan, Inc. | N-(1-phenyl-2-arylethyl)-4,5-dihydro-3h-pyrrol-2-amine compounds as subtype selective modulators of alpha2b or alpha2b and alpha2c adrenoceptors |
| DK3562486T3 (da) | 2016-12-31 | 2024-06-10 | Bioxcel Therapeutics Inc | Anvendelse af sublingual dexmedetomidin til behandling af agitation |
| CA3103431A1 (en) | 2018-06-27 | 2020-01-02 | Bioxcel Therapeutics, Inc. | Film formulations containing dexmedetomidine and methods of producing them |
| MX2022000709A (es) | 2019-07-19 | 2022-05-19 | Bioxcel Therapeutics Inc | Regimenes de tratamiento con dexmedetomidina no sedante. |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795970A (fr) * | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
| US4029792A (en) * | 1972-02-29 | 1977-06-14 | Pfizer Inc. | (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents |
| US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
| US6194415B1 (en) * | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
| ES2216339T3 (es) * | 1997-12-04 | 2004-10-16 | Allergan, Inc. | Derivados sustituidos de imidazol que tienen actividad de tipo agonista hacia los receptores adrenergicos alfa 2b o 2b/2c. |
| US6841684B2 (en) * | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
| US6329369B1 (en) * | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
| US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
| WO2002005853A2 (en) * | 2000-07-14 | 2002-01-24 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
| AU2002248284A1 (en) * | 2000-11-01 | 2002-08-06 | Allergan, Inc. | Compositions for treatment of ocular neovascularization |
| US7091232B2 (en) * | 2002-05-21 | 2006-08-15 | Allergan, Inc. | 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds |
-
2003
- 2003-10-07 EP EP03774642A patent/EP1549305B1/en not_active Expired - Lifetime
- 2003-10-07 CA CA002501347A patent/CA2501347A1/en not_active Abandoned
- 2003-10-07 AU AU2003282758A patent/AU2003282758A1/en not_active Abandoned
- 2003-10-07 ES ES03774642T patent/ES2322954T3/es not_active Expired - Lifetime
- 2003-10-07 US US10/680,879 patent/US20040138312A1/en not_active Abandoned
- 2003-10-07 JP JP2004543495A patent/JP4724421B2/ja not_active Expired - Fee Related
- 2003-10-07 AT AT03774642T patent/ATE429216T1/de not_active IP Right Cessation
- 2003-10-07 PL PL376346A patent/PL216373B1/pl unknown
- 2003-10-07 KR KR1020057006114A patent/KR20050050124A/ko not_active Abandoned
- 2003-10-07 CN CNB200380101115XA patent/CN100431536C/zh not_active Expired - Fee Related
- 2003-10-07 WO PCT/US2003/031809 patent/WO2004032913A1/en not_active Ceased
- 2003-10-07 MX MXPA05003664A patent/MXPA05003664A/es active IP Right Grant
- 2003-10-07 RU RU2005114504/14A patent/RU2330649C2/ru not_active IP Right Cessation
- 2003-10-07 BR BR0314540-9A patent/BR0314540A/pt not_active Application Discontinuation
- 2003-10-07 NZ NZ539328A patent/NZ539328A/en not_active IP Right Cessation
- 2003-10-07 DE DE60327335T patent/DE60327335D1/de not_active Expired - Lifetime
-
2005
- 2005-04-04 NO NO20051663A patent/NO20051663L/no unknown
- 2005-04-04 IL IL167849A patent/IL167849A/en active IP Right Grant
- 2005-04-05 ZA ZA200502744A patent/ZA200502744B/en unknown
-
2009
- 2009-11-20 AU AU2009238370A patent/AU2009238370B2/en not_active Ceased
-
2010
- 2010-12-03 JP JP2010270724A patent/JP2011057700A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050050124A (ko) | 2005-05-27 |
| AU2009238370B2 (en) | 2011-07-21 |
| ES2322954T3 (es) | 2009-07-02 |
| NZ539328A (en) | 2007-01-26 |
| ZA200502744B (en) | 2006-02-22 |
| AU2009238370A1 (en) | 2009-12-17 |
| RU2330649C2 (ru) | 2008-08-10 |
| JP4724421B2 (ja) | 2011-07-13 |
| HK1081880A1 (zh) | 2006-05-26 |
| RU2005114504A (ru) | 2005-10-27 |
| ATE429216T1 (de) | 2009-05-15 |
| DE60327335D1 (de) | 2009-06-04 |
| IL167849A (en) | 2011-04-28 |
| PL376346A1 (en) | 2005-12-27 |
| MXPA05003664A (es) | 2005-06-08 |
| JP2011057700A (ja) | 2011-03-24 |
| CN100431536C (zh) | 2008-11-12 |
| US20040138312A1 (en) | 2004-07-15 |
| BR0314540A (pt) | 2005-07-26 |
| CA2501347A1 (en) | 2004-04-22 |
| AU2003282758A1 (en) | 2004-05-04 |
| CN1703213A (zh) | 2005-11-30 |
| WO2004032913A1 (en) | 2004-04-22 |
| PL216373B1 (pl) | 2014-03-31 |
| EP1549305A1 (en) | 2005-07-06 |
| EP1549305B1 (en) | 2009-04-22 |
| JP2006504739A (ja) | 2006-02-09 |
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