HK1073060A1 - Topical composition for follicular delivery of an ornithine decarboxylase inhibitor - Google Patents
Topical composition for follicular delivery of an ornithine decarboxylase inhibitorInfo
- Publication number
- HK1073060A1 HK1073060A1 HK05104992A HK05104992A HK1073060A1 HK 1073060 A1 HK1073060 A1 HK 1073060A1 HK 05104992 A HK05104992 A HK 05104992A HK 05104992 A HK05104992 A HK 05104992A HK 1073060 A1 HK1073060 A1 HK 1073060A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sub
- ornithine decarboxylase
- follicular
- topical composition
- decarboxylase inhibitor
- Prior art date
Links
- 230000003325 follicular Effects 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000002818 ornithine decarboxylase inhibitor Substances 0.000 title abstract 2
- 229940122060 Ornithine decarboxylase inhibitor Drugs 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 2
- JKXYOQDLERSFPT-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-octadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO JKXYOQDLERSFPT-UHFFFAOYSA-N 0.000 abstract 1
- ICIDSZQHPUZUHC-UHFFFAOYSA-N 2-octadecoxyethanol Chemical compound CCCCCCCCCCCCCCCCCCOCCO ICIDSZQHPUZUHC-UHFFFAOYSA-N 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 125000005233 alkylalcohol group Chemical group 0.000 abstract 1
- 229940073669 ceteareth 20 Drugs 0.000 abstract 1
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- 229960000502 poloxamer Drugs 0.000 abstract 1
- 229920001992 poloxamer 407 Polymers 0.000 abstract 1
- 229940044476 poloxamer 407 Drugs 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940100459 steareth-20 Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31265701P | 2001-08-15 | 2001-08-15 | |
| PCT/US2002/025754 WO2003015729A1 (en) | 2001-08-15 | 2002-08-13 | Topical composition for follicular delivery of an ornithine decarboxylase inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1073060A1 true HK1073060A1 (en) | 2005-09-23 |
Family
ID=23212429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK05104992A HK1073060A1 (en) | 2001-08-15 | 2005-06-15 | Topical composition for follicular delivery of an ornithine decarboxylase inhibitor |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7374770B2 (es) |
| EP (1) | EP1416907A4 (es) |
| JP (1) | JP3981074B2 (es) |
| KR (1) | KR100722001B1 (es) |
| CN (1) | CN1320878C (es) |
| AR (1) | AR035133A1 (es) |
| AU (1) | AU2002324699B2 (es) |
| CA (1) | CA2455231C (es) |
| HK (1) | HK1073060A1 (es) |
| IL (2) | IL160131A0 (es) |
| MX (1) | MXPA04001137A (es) |
| NZ (1) | NZ531006A (es) |
| RU (1) | RU2004107843A (es) |
| WO (1) | WO2003015729A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7261878B2 (en) | 2001-08-10 | 2007-08-28 | The Gillette Company | Reduction of hair growth |
| US6743822B2 (en) | 2001-08-10 | 2004-06-01 | The Gillette Company | Reduction of hair growth |
| US20030036561A1 (en) * | 2001-08-10 | 2003-02-20 | Peter Styczynski | Reduction of hair growth |
| US20030199584A1 (en) * | 2002-04-11 | 2003-10-23 | Ahluwalia Gurpreet S. | Reduction of hair growth |
| US7015349B2 (en) * | 2003-03-26 | 2006-03-21 | The Gillette Company | Reduction of hair growth |
| JP4390809B2 (ja) | 2004-01-07 | 2009-12-24 | イーエルシー マネージメント エルエルシー | 発毛遅延のための化粧品組成物及び方法 |
| ATE451950T1 (de) * | 2004-06-14 | 2010-01-15 | Unilever Nv | Verfahren zur verminderung der talgproduktion und porengrösse |
| EP2212442A1 (en) * | 2007-10-26 | 2010-08-04 | Galderma Research & Development | Non-invasive method to perform skin inflammatory disease pharmaco-genomic studies and diagnosis method thereof |
| KR101035086B1 (ko) | 2009-07-13 | 2011-05-19 | (주)넥스젠바이오텍 | 담배거세미나방 유래의 ＯＤＣ Ａｚ 단백질 코딩 유전자 및 이의 용도 |
| KR101035085B1 (ko) | 2009-07-13 | 2011-05-19 | (주)넥스젠바이오텍 | 담배거세미나방 유래의 ｏｄｃ 단백질 코딩 유전자 및 이의 용도 |
| NZ628126A (en) | 2012-02-16 | 2016-10-28 | Atyr Pharma Inc | Histidyl-trna synthetases for treating autoimmune and inflammatory diseases |
| ITRM20120576A1 (it) * | 2012-11-19 | 2014-05-20 | Cinzia Marchese | Composizione efficace nel rallentamento della crescita pilifera |
| NZ752894A (en) * | 2016-10-06 | 2023-05-26 | Orbus Therapeutics Inc | Formulations for administration of eflornithine |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3925012A (en) * | 1968-08-02 | 1975-12-09 | Bayer Ag | Process for dyeing fibre material containing nh-groups from organic solvents |
| US4201788A (en) | 1976-10-20 | 1980-05-06 | University Patents, Inc. | Process for alleviating proliferative skin diseases |
| US4496588A (en) | 1977-07-11 | 1985-01-29 | Merrell Toraude Et Compagnie | Method of treating psoriasis |
| US4413141A (en) | 1977-07-11 | 1983-11-01 | Merrell Toraude Et Compagnie | 2-(Difluoromethyl)-2,5-diaminopentanoic acid |
| US4421768A (en) | 1982-08-11 | 1983-12-20 | Merrell Toraude Et Compagnie | Fluorinated diamino-heptene and-heptyne derivatives |
| US4720489A (en) | 1984-10-15 | 1988-01-19 | Douglas Shander | Hair growth modification with ornithine decarboxylase inhibitors |
| JP2652870B2 (ja) | 1988-04-06 | 1997-09-10 | 鐘紡株式会社 | 泡状除毛組成物 |
| US5217886A (en) | 1988-08-31 | 1993-06-08 | Merrell Dow Pharmaceuticals Inc. | Method for the production of (-)-4-difluoromethyl-ornithine |
| US5256396A (en) | 1990-01-24 | 1993-10-26 | Colgate-Palmolive Company | Topical composition |
| US5096911A (en) | 1990-06-25 | 1992-03-17 | Ahluwalia Gurpreet S | Alteration of rate and character of hair growth |
| JPH0495019A (ja) | 1990-08-10 | 1992-03-27 | Shiseido Co Ltd | 崩壊性泡状除毛剤 |
| ES2109949T3 (es) | 1990-08-14 | 1998-02-01 | Joseph H Handelman | Alteracion enzimatica del crecimiento del pelo. |
| US5095007A (en) | 1990-10-24 | 1992-03-10 | Ahluwalia Gurpreet S | Alteration of rate and character of hair growth |
| JP2986274B2 (ja) | 1991-12-24 | 1999-12-06 | 鐘紡株式会社 | クリーム状除毛剤組成物 |
| WO1994021216A1 (en) | 1993-03-19 | 1994-09-29 | Handelman, Joseph, H. | Topical composition for inhibiting hair growth |
| US5648394A (en) * | 1993-05-27 | 1997-07-15 | Boxall; Brian Alfred | Topical composition for inhibiting hair growth |
| US5945409A (en) * | 1995-03-10 | 1999-08-31 | Wilson T. Crandall | Topical moisturizing composition and method |
| US5851537A (en) | 1996-02-02 | 1998-12-22 | Cancer Technologies, Inc. | Topical application of α-DFMO for preventing skin cancer |
| WO1998025603A1 (en) | 1996-12-13 | 1998-06-18 | Ilex Oncology, Inc. | Isomeric pharmaceutical formulation containing dfmo for the treatment of cancer |
| JPH11267105A (ja) | 1998-03-23 | 1999-10-05 | Shiseido Co Ltd | 皮膚の測定方法及びこの方法に用いる蛍光色素浸潤用組成物 |
| US7261878B2 (en) | 2001-08-10 | 2007-08-28 | The Gillette Company | Reduction of hair growth |
| US20030036561A1 (en) * | 2001-08-10 | 2003-02-20 | Peter Styczynski | Reduction of hair growth |
-
2002
- 2002-08-13 US US10/219,087 patent/US7374770B2/en active Active
- 2002-08-13 CA CA002455231A patent/CA2455231C/en not_active Expired - Fee Related
- 2002-08-13 IL IL16013102A patent/IL160131A0/xx unknown
- 2002-08-13 JP JP2003520689A patent/JP3981074B2/ja not_active Expired - Fee Related
- 2002-08-13 AU AU2002324699A patent/AU2002324699B2/en not_active Ceased
- 2002-08-13 RU RU2004107843/15A patent/RU2004107843A/ru not_active Application Discontinuation
- 2002-08-13 EP EP02759357A patent/EP1416907A4/en not_active Withdrawn
- 2002-08-13 MX MXPA04001137A patent/MXPA04001137A/es active IP Right Grant
- 2002-08-13 WO PCT/US2002/025754 patent/WO2003015729A1/en active IP Right Grant
- 2002-08-13 KR KR1020047002172A patent/KR100722001B1/ko not_active IP Right Cessation
- 2002-08-13 NZ NZ531006A patent/NZ531006A/en not_active IP Right Cessation
- 2002-08-13 CN CNB028181697A patent/CN1320878C/zh not_active Expired - Fee Related
- 2002-08-15 AR ARP020103073A patent/AR035133A1/es not_active Application Discontinuation
-
2004
- 2004-01-29 IL IL160131A patent/IL160131A/en not_active IP Right Cessation
-
2005
- 2005-06-15 HK HK05104992A patent/HK1073060A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005505528A (ja) | 2005-02-24 |
| CA2455231A1 (en) | 2003-02-27 |
| US20030053973A1 (en) | 2003-03-20 |
| RU2004107843A (ru) | 2005-04-10 |
| EP1416907A1 (en) | 2004-05-12 |
| AR035133A1 (es) | 2004-04-14 |
| JP3981074B2 (ja) | 2007-09-26 |
| CN1555252A (zh) | 2004-12-15 |
| KR20040054672A (ko) | 2004-06-25 |
| EP1416907A4 (en) | 2005-07-20 |
| NZ531006A (en) | 2005-01-28 |
| MXPA04001137A (es) | 2005-02-17 |
| CN1320878C (zh) | 2007-06-13 |
| IL160131A (en) | 2011-05-31 |
| KR100722001B1 (ko) | 2007-05-25 |
| IL160131A0 (en) | 2004-06-20 |
| US7374770B2 (en) | 2008-05-20 |
| AU2002324699B2 (en) | 2007-07-26 |
| WO2003015729A1 (en) | 2003-02-27 |
| CA2455231C (en) | 2007-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110813 |