HK1071125A1 - Modafinil synthesis process - Google Patents

Modafinil synthesis process

Info

Publication number
HK1071125A1
HK1071125A1 HK05103847.4A HK05103847A HK1071125A1 HK 1071125 A1 HK1071125 A1 HK 1071125A1 HK 05103847 A HK05103847 A HK 05103847A HK 1071125 A1 HK1071125 A1 HK 1071125A1
Authority
HK
Hong Kong
Prior art keywords
synthesis process
modafinil
modafinil synthesis
synthesis
Prior art date
Application number
HK05103847.4A
Other languages
English (en)
Inventor
Sebastien Rose
Original Assignee
Cephalon France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33017031&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1071125(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon France filed Critical Cephalon France
Publication of HK1071125A1 publication Critical patent/HK1071125A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK05103847.4A 2003-05-16 2005-05-06 Modafinil synthesis process HK1071125A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03291152A EP1477476B1 (en) 2003-05-16 2003-05-16 Modafinil synthesis process

Publications (1)

Publication Number Publication Date
HK1071125A1 true HK1071125A1 (en) 2005-07-08

Family

ID=33017031

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103847.4A HK1071125A1 (en) 2003-05-16 2005-05-06 Modafinil synthesis process

Country Status (19)

Country Link
US (1) US7541493B2 (zh)
EP (1) EP1477476B1 (zh)
JP (1) JP4825673B2 (zh)
KR (1) KR101054262B1 (zh)
CN (1) CN100400507C (zh)
AR (1) AR044329A1 (zh)
AT (1) ATE442352T1 (zh)
AU (1) AU2004238636B2 (zh)
CA (1) CA2525317C (zh)
CL (1) CL2004001052A1 (zh)
DE (1) DE60329167D1 (zh)
ES (1) ES2330321T3 (zh)
HK (1) HK1071125A1 (zh)
IL (1) IL171588A (zh)
MX (1) MXPA05012213A (zh)
NZ (1) NZ543237A (zh)
TW (1) TWI334861B (zh)
WO (1) WO2004101503A1 (zh)
ZA (1) ZA200508714B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020032023A (ko) * 2000-10-25 2002-05-03 이성식 저공해 환경 연료
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
EP1702915A1 (en) 2005-03-14 2006-09-20 Cephalon France Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation
US7960586B2 (en) * 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
JPWO2011115136A1 (ja) * 2010-03-16 2013-06-27 三菱化学株式会社 コハク酸の製造方法
CN103412062A (zh) * 2013-07-17 2013-11-27 张家港威胜生物医药有限公司 一种测定莫达非尼含量的高效液相色谱法
US9616068B2 (en) 2014-10-27 2017-04-11 Pohela LLC Animal training using cognitive enhancement

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
FR2707637B1 (fr) * 1993-06-30 1995-10-06 Lafon Labor Nouveaux dérivés d'acétamide, leur procédé de préparation et leur utilisation en thérapeutique.
US5618845A (en) * 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
JP2002020379A (ja) * 2000-05-02 2002-01-23 Sumika Fine Chemicals Co Ltd シタロプラム臭化水素酸塩の結晶およびその結晶化方法
DE10034802A1 (de) * 2000-07-18 2002-01-31 Bayer Ag Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren
JP4302977B2 (ja) * 2000-07-27 2009-07-29 テバ ファーマシューティカル インダストリーズ リミティド 結晶性の且つ純粋なモダフィニルおよびそれを製造する方法
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
JP3838972B2 (ja) * 2002-12-25 2006-10-25 Ｎｅｃエレクトロニクス株式会社 周波数検出回路及びデータ処理装置

Also Published As

Publication number Publication date
EP1477476A1 (en) 2004-11-17
CN1791571A (zh) 2006-06-21
AU2004238636B2 (en) 2010-12-16
KR20060017600A (ko) 2006-02-24
AR044329A1 (es) 2005-09-07
TW200510287A (en) 2005-03-16
CA2525317C (en) 2012-07-10
DE60329167D1 (de) 2009-10-22
ATE442352T1 (de) 2009-09-15
EP1477476A8 (en) 2005-06-22
WO2004101503A1 (en) 2004-11-25
JP4825673B2 (ja) 2011-11-30
TWI334861B (en) 2010-12-21
IL171588A (en) 2011-02-28
ZA200508714B (en) 2006-07-26
KR101054262B1 (ko) 2011-08-08
NZ543237A (en) 2009-04-30
US20070015836A1 (en) 2007-01-18
ES2330321T3 (es) 2009-12-09
EP1477476B1 (en) 2009-09-09
CL2004001052A1 (es) 2005-01-28
JP2006528966A (ja) 2006-12-28
MXPA05012213A (es) 2006-02-08
US7541493B2 (en) 2009-06-02
AU2004238636A1 (en) 2004-11-25
CN100400507C (zh) 2008-07-09
CA2525317A1 (en) 2004-11-25

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160516