HK1059436A1 - New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates - Google Patents

New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates

Info

Publication number
HK1059436A1
HK1059436A1 HK04102254.3A HK04102254A HK1059436A1 HK 1059436 A1 HK1059436 A1 HK 1059436A1 HK 04102254 A HK04102254 A HK 04102254A HK 1059436 A1 HK1059436 A1 HK 1059436A1
Authority
HK
Hong Kong
Prior art keywords
asymmetric
diarylmethylpiperazines
preparation
diarylmetylamines
intermediates
Prior art date
Application number
HK04102254.3A
Other languages
English (en)
Inventor
William Brown
Niklas Plobeck
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1059436A1 publication Critical patent/HK1059436A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Quinoline Compounds (AREA)
HK04102254.3A 2001-03-07 2004-03-26 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates HK1059436A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100764A SE0100764D0 (sv) 2001-03-07 2001-03-07 New assymetric process
PCT/SE2002/000376 WO2002070492A1 (en) 2001-03-07 2002-03-05 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates

Publications (1)

Publication Number Publication Date
HK1059436A1 true HK1059436A1 (en) 2004-07-02

Family

ID=20283236

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04102254.3A HK1059436A1 (en) 2001-03-07 2004-03-26 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates

Country Status (21)

Country Link
US (2) US7045625B2 (no)
EP (1) EP1368325B1 (no)
JP (1) JP2004522793A (no)
KR (1) KR100856996B1 (no)
CN (2) CN1244565C (no)
AT (1) ATE406354T1 (no)
BR (1) BR0207817A (no)
CA (1) CA2440104A1 (no)
DE (1) DE60228548D1 (no)
DK (1) DK1368325T3 (no)
ES (1) ES2311050T3 (no)
HK (1) HK1059436A1 (no)
IL (1) IL157460A0 (no)
MX (1) MXPA03007889A (no)
NO (1) NO325156B1 (no)
NZ (1) NZ527656A (no)
PT (1) PT1368325E (no)
SE (1) SE0100764D0 (no)
SI (1) SI1368325T1 (no)
WO (1) WO2002070492A1 (no)
ZA (1) ZA200306448B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114560781A (zh) * 2022-03-01 2022-05-31 无锡捷化医药科技有限公司 一种n,n-二(2-氯乙基)-4-硝基苯基丙氨酸甲酯的制备方法
CN114702457A (zh) * 2022-03-30 2022-07-05 青岛科技大学 一种二芳基甲胺类化合物的绿色合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
DK0711289T3 (da) * 1993-07-30 2000-11-06 Delta Pharmaceuticals Inc Piperazinforbindelser til anvendelse i terapi
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
SE0100764D0 (sv) 2001-03-07
CN1721407A (zh) 2006-01-18
JP2004522793A (ja) 2004-07-29
NO325156B1 (no) 2008-02-11
PT1368325E (pt) 2008-10-27
NO20033944D0 (no) 2003-09-05
US7423154B2 (en) 2008-09-09
DK1368325T3 (da) 2008-11-24
CN1494532A (zh) 2004-05-05
NO20033944L (no) 2003-10-31
US7045625B2 (en) 2006-05-16
KR20030080075A (ko) 2003-10-10
ZA200306448B (en) 2004-09-08
DE60228548D1 (de) 2008-10-09
CA2440104A1 (en) 2002-09-12
NZ527656A (en) 2005-04-29
MXPA03007889A (es) 2003-12-04
CN1295217C (zh) 2007-01-17
IL157460A0 (en) 2004-03-28
ES2311050T3 (es) 2009-02-01
ATE406354T1 (de) 2008-09-15
EP1368325B1 (en) 2008-08-27
EP1368325A1 (en) 2003-12-10
SI1368325T1 (sl) 2008-12-31
WO2002070492A1 (en) 2002-09-12
BR0207817A (pt) 2004-03-09
US20060074238A1 (en) 2006-04-06
KR100856996B1 (ko) 2008-09-04
US20040077861A1 (en) 2004-04-22
CN1244565C (zh) 2006-03-08

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130305