HK1052698B - 取代的8，8a-二氫-3ah-茚並[1，2-d]噻唑、它們的製備方法和它們作為藥物的用途 - Google Patents

取代的8，8a-二氫-3ah-茚並[1，2-d]噻唑、它們的製備方法和它們作為藥物的用途

Info

Publication number
HK1052698B
HK1052698B HK03104948.2A HK03104948A HK1052698B HK 1052698 B HK1052698 B HK 1052698B HK 03104948 A HK03104948 A HK 03104948A HK 1052698 B HK1052698 B HK 1052698B
Authority
HK
Hong Kong
Prior art keywords
indeno
thiazoles
dihydro
substituted
medicaments
Prior art date
Application number
HK03104948.2A
Other languages
English (en)
Other versions
HK1052698A1 (en
Inventor
G‧加恩
H-J‧蘭格
M‧高塞爾
M‧比克爾
Original Assignee
阿文蒂斯藥物德國有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 阿文蒂斯藥物德國有限公司 filed Critical 阿文蒂斯藥物德國有限公司
Publication of HK1052698A1 publication Critical patent/HK1052698A1/xx
Publication of HK1052698B publication Critical patent/HK1052698B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK03104948.2A 2000-02-23 2003-07-09 取代的8，8a-二氫-3ah-茚並[1，2-d]噻唑、它們的製備方法和它們作為藥物的用途 HK1052698B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10008274A DE10008274A1 (de) 2000-02-23 2000-02-23 Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP2001/001498 WO2001062745A1 (de) 2000-02-23 2001-02-12 SUBSTITUIERTE 8,8a-DIHYDRO-3aH-INDENO[1,2-d]THIAZOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL

Publications (2)

Publication Number Publication Date
HK1052698A1 HK1052698A1 (en) 2003-09-26
HK1052698B true HK1052698B (zh) 2005-04-22

Family

ID=7631988

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03104948.2A HK1052698B (zh) 2000-02-23 2003-07-09 取代的8，8a-二氫-3ah-茚並[1，2-d]噻唑、它們的製備方法和它們作為藥物的用途

Country Status (25)

Country Link
US (1) US6410577B2 (zh)
EP (1) EP1263746B1 (zh)
JP (1) JP4898051B2 (zh)
KR (1) KR20020072583A (zh)
CN (1) CN1159306C (zh)
AT (1) ATE314353T1 (zh)
AU (2) AU3173101A (zh)
BR (1) BR0108535A (zh)
CA (1) CA2400692A1 (zh)
CZ (1) CZ20022837A3 (zh)
DE (2) DE10008274A1 (zh)
EE (1) EE200200465A (zh)
HK (1) HK1052698B (zh)
HR (1) HRP20020689A2 (zh)
HU (1) HUP0302024A3 (zh)
IL (1) IL151326A0 (zh)
MX (1) MXPA02007022A (zh)
NO (1) NO20023955L (zh)
NZ (1) NZ520925A (zh)
PL (1) PL357558A1 (zh)
RU (1) RU2263669C2 (zh)
SK (1) SK12142002A3 (zh)
WO (1) WO2001062745A1 (zh)
YU (1) YU57902A (zh)
ZA (1) ZA200206486B (zh)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507868A (en) * 1968-10-21 1970-04-21 Sandoz Ag Imidazo(2,1-b)thiazoles and thiazolo(3,2-a)pyrimidines
SE7700500L (sv) * 1976-01-20 1977-07-21 Hoechst Ag Tiazolidinderivat och forfarande for deras framstellning
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
CN1143364A (zh) * 1994-03-11 1997-02-19 山之内制药株式会社 5-ht3受体激动剂、新颖的噻唑衍生物及其中间体
DE19844547C2 (de) * 1998-09-29 2002-11-07 Aventis Pharma Gmbh Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908539A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
NO20023955L (no) 2002-09-19
ZA200206486B (en) 2003-05-12
CA2400692A1 (en) 2001-08-30
KR20020072583A (ko) 2002-09-16
YU57902A (sh) 2005-11-28
HUP0302024A3 (en) 2006-07-28
ATE314353T1 (de) 2006-01-15
CN1159306C (zh) 2004-07-28
CN1404473A (zh) 2003-03-19
RU2263669C2 (ru) 2005-11-10
RU2002125448A (ru) 2004-01-10
EP1263746A1 (de) 2002-12-11
MXPA02007022A (es) 2003-03-27
NO20023955D0 (no) 2002-08-20
WO2001062745A1 (de) 2001-08-30
US20010031752A1 (en) 2001-10-18
NZ520925A (en) 2004-08-27
HK1052698A1 (en) 2003-09-26
BR0108535A (pt) 2003-04-22
AU3173101A (en) 2001-09-03
CZ20022837A3 (cs) 2002-11-13
PL357558A1 (en) 2004-07-26
SK12142002A3 (sk) 2003-03-04
JP4898051B2 (ja) 2012-03-14
EP1263746B1 (de) 2005-12-28
US6410577B2 (en) 2002-06-25
IL151326A0 (en) 2003-04-10
DE10008274A1 (de) 2001-08-30
EE200200465A (et) 2003-12-15
DE50108546D1 (de) 2006-02-02
HRP20020689A2 (en) 2004-12-31
AU2001231731B2 (en) 2005-04-07
JP2004529064A (ja) 2004-09-24
HUP0302024A2 (hu) 2003-09-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090212