HK1052302A1 - 异维甲酸的生物可利用剂型 - Google Patents

异维甲酸的生物可利用剂型 Download PDF

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Publication number
HK1052302A1
HK1052302A1 HK03104641.2A HK03104641A HK1052302A1 HK 1052302 A1 HK1052302 A1 HK 1052302A1 HK 03104641 A HK03104641 A HK 03104641A HK 1052302 A1 HK1052302 A1 HK 1052302A1
Authority
HK
Hong Kong
Prior art keywords
acid
formulation
microns
less
particle size
Prior art date
Application number
HK03104641.2A
Other languages
English (en)
Chinese (zh)
Inventor
A‧潘特
I‧巴蒂亚
S‧B‧罗伊
I‧巴蒂亞
R‧马立克
S‧B‧羅伊
R‧馬立克
Original Assignee
兰贝克塞实验室有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 兰贝克塞实验室有限公司 filed Critical 兰贝克塞实验室有限公司
Publication of HK1052302A1 publication Critical patent/HK1052302A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK03104641.2A 2000-06-16 2001-04-09 异维甲酸的生物可利用剂型 HK1052302A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN596/DEL/00 2000-06-16
IN596DE2000 IN192188B (enExample) 2000-06-16 2000-06-16
PCT/IB2001/000581 WO2001095886A1 (en) 2000-06-16 2001-04-09 Bioavailable dosage form of isotretinoin

Publications (1)

Publication Number Publication Date
HK1052302A1 true HK1052302A1 (zh) 2003-09-11

Family

ID=11097063

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03104641.2A HK1052302A1 (zh) 2000-06-16 2001-04-09 异维甲酸的生物可利用剂型

Country Status (25)

Country Link
US (1) US6740337B2 (enExample)
EP (1) EP1294357A1 (enExample)
JP (1) JP2004503493A (enExample)
CN (1) CN1196475C (enExample)
AP (1) AP2002002423A0 (enExample)
AU (1) AU782094B2 (enExample)
BG (1) BG106414A (enExample)
BR (1) BR0106752A (enExample)
CA (1) CA2382065A1 (enExample)
CZ (1) CZ2002694A3 (enExample)
EA (1) EA004808B1 (enExample)
EE (1) EE200200074A (enExample)
HK (1) HK1052302A1 (enExample)
HR (1) HRP20020148A2 (enExample)
HU (1) HUP0203717A3 (enExample)
IL (1) IL148176A0 (enExample)
IN (1) IN192188B (enExample)
MX (1) MXPA02001669A (enExample)
NZ (1) NZ517142A (enExample)
OA (1) OA12008A (enExample)
PL (1) PL352838A1 (enExample)
SK (1) SK2252002A3 (enExample)
UA (1) UA74793C2 (enExample)
WO (1) WO2001095886A1 (enExample)
ZA (1) ZA200201240B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2225600T3 (es) * 2000-09-22 2005-03-16 Galephar M/F Composicion semi-solida de isotretinoina.
EP1527774A1 (en) 2003-11-03 2005-05-04 Basilea Pharmaceutica AG New formulation for retinoid-containing soft gelatin capsules
US20070099996A1 (en) * 2003-05-20 2007-05-03 Shashikanth Isloor Pharmaceutical compositions of acitretin
US20070254858A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects
US20070254025A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Oral contraceptive and acne medication combination and treatment of acne with reduced side effects
RU2322998C1 (ru) * 2006-11-16 2008-04-27 Общество с ограниченной ответственностью "Березовый мир" Носитель лекарственных и диагностических средств
KR101434706B1 (ko) * 2007-02-16 2014-08-26 아스카 세이야쿠 가부시키가이샤 미립자 유성 현탁액을 포함하는 의약 조성물
WO2008102375A2 (en) * 2007-02-20 2008-08-28 Ipca Laboratories Limited A process for preparation of highly pure isotretinoin
US9078925B2 (en) 2012-06-18 2015-07-14 Galephar Pharmaceutical Research, Inc. Pharmaceutical semi-solid composition of isotretinoin
CA2987177A1 (en) * 2015-05-25 2016-12-01 Sun Pharmaceutical Industries Limited Once-daily oral pharmaceutical composition of isotretinoin
US10517846B2 (en) 2016-05-26 2019-12-31 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for treating acne
KR20250054055A (ko) * 2022-07-01 2025-04-22 아크로테크 바이오파마 인코포레이티드. 이소트레티노인을 포함하는 제약 조성물 및 그의 제조 방법 및 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016254A (en) * 1972-05-19 1977-04-05 Beecham Group Limited Pharmaceutical formulations
CA1282326C (en) * 1984-12-14 1991-04-02 Paul J. Jarosz Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
US4808630A (en) 1987-01-16 1989-02-28 United States Of America Method of treating psychotic illnesses
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
PE20001227A1 (es) * 1998-10-30 2000-11-06 Hoffmann La Roche Procesos para producir una composicion de isotretinoina
US6284283B1 (en) * 1999-10-21 2001-09-04 Alkermes Controlled Therapeutics, Inc. Method of producing sub-micron particles of biologically active agents and uses thereof

Also Published As

Publication number Publication date
EA004808B1 (ru) 2004-08-26
HRP20020148A2 (en) 2003-12-31
SK2252002A3 (en) 2002-08-06
WO2001095886A1 (en) 2001-12-20
EE200200074A (et) 2003-04-15
US20020025338A1 (en) 2002-02-28
ZA200201240B (en) 2002-09-02
IL148176A0 (en) 2002-09-12
UA74793C2 (en) 2006-02-15
BR0106752A (pt) 2002-04-16
MXPA02001669A (es) 2002-08-06
CN1196475C (zh) 2005-04-13
CN1388757A (zh) 2003-01-01
OA12008A (en) 2006-04-19
AU4445901A (en) 2001-12-24
CZ2002694A3 (cs) 2002-08-14
AP2002002423A0 (en) 2002-03-31
EA200200166A1 (ru) 2002-10-31
US6740337B2 (en) 2004-05-25
HUP0203717A3 (en) 2003-05-28
HUP0203717A2 (hu) 2003-04-28
IN192188B (enExample) 2004-03-13
AU782094B2 (en) 2005-06-30
PL352838A1 (en) 2003-09-08
CA2382065A1 (en) 2001-12-20
JP2004503493A (ja) 2004-02-05
NZ517142A (en) 2003-08-29
EP1294357A1 (en) 2003-03-26
BG106414A (en) 2002-09-30

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