HK1043507B - 用於治疗细胞增殖性紊乱的组合物及其用途 - Google Patents

用於治疗细胞增殖性紊乱的组合物及其用途 Download PDF

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Publication number
HK1043507B
HK1043507B HK02104737.8A HK02104737A HK1043507B HK 1043507 B HK1043507 B HK 1043507B HK 02104737 A HK02104737 A HK 02104737A HK 1043507 B HK1043507 B HK 1043507B
Authority
HK
Hong Kong
Prior art keywords
glcnac
composition
endothelin
endothelin antagonist
poly
Prior art date
Application number
HK02104737.8A
Other languages
English (en)
Chinese (zh)
Other versions
HK1043507A1 (zh
Inventor
N. Vournakis John
Finkielsztein Sergio
R. Pariser Ernest
Original Assignee
海洋聚合物技术公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 海洋聚合物技术公司 filed Critical 海洋聚合物技术公司
Publication of HK1043507A1 publication Critical patent/HK1043507A1/xx
Publication of HK1043507B publication Critical patent/HK1043507B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
HK02104737.8A 1998-12-22 1999-12-21 用於治疗细胞增殖性紊乱的组合物及其用途 HK1043507B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/218,288 US6063911A (en) 1993-12-01 1998-12-22 Methods and compositions for treatment of cell proliferative disorders
US09/218,288 1998-12-22
PCT/US1999/030575 WO2000036918A1 (en) 1998-12-22 1999-12-21 Methods and compositions for treatment of cell proliferative disorders

Publications (2)

Publication Number Publication Date
HK1043507A1 HK1043507A1 (zh) 2002-09-20
HK1043507B true HK1043507B (zh) 2009-12-24

Family

ID=22814511

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02104737.8A HK1043507B (zh) 1998-12-22 1999-12-21 用於治疗细胞增殖性紊乱的组合物及其用途

Country Status (14)

Country Link
US (1) US6063911A (enExample)
EP (1) EP1139752B1 (enExample)
JP (1) JP4795539B2 (enExample)
CN (1) CN100488512C (enExample)
AT (1) ATE294504T1 (enExample)
AU (1) AU780248B2 (enExample)
CA (1) CA2356087C (enExample)
DE (1) DE69925156T2 (enExample)
ES (1) ES2242448T3 (enExample)
HK (1) HK1043507B (enExample)
IL (2) IL143700A0 (enExample)
NO (1) NO330033B1 (enExample)
NZ (1) NZ512586A (enExample)
WO (1) WO2000036918A1 (enExample)

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Also Published As

Publication number Publication date
JP4795539B2 (ja) 2011-10-19
EP1139752B1 (en) 2005-05-04
NO20013071D0 (no) 2001-06-20
AU2591900A (en) 2000-07-12
CA2356087A1 (en) 2000-06-29
US6063911A (en) 2000-05-16
AU780248B2 (en) 2005-03-10
IL143700A (en) 2006-08-01
ES2242448T3 (es) 2005-11-01
WO2000036918A9 (en) 2000-11-23
NO20013071L (no) 2001-08-20
DE69925156T2 (de) 2006-02-16
IL143700A0 (en) 2002-04-21
NZ512586A (en) 2004-01-30
DE69925156D1 (de) 2005-06-09
CN1335749A (zh) 2002-02-13
CN100488512C (zh) 2009-05-20
CA2356087C (en) 2009-02-17
JP2003522732A (ja) 2003-07-29
NO330033B1 (no) 2011-02-07
HK1043507A1 (zh) 2002-09-20
ATE294504T1 (de) 2005-05-15
EP1139752A4 (en) 2003-01-02
WO2000036918A1 (en) 2000-06-29
EP1139752A1 (en) 2001-10-10

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Effective date: 20191220