HK1032534A1 - L-threonate ferrous, as well as pharmaceutical composition and use for improving and treating human anemia thereof - Google Patents

L-threonate ferrous, as well as pharmaceutical composition and use for improving and treating human anemia thereof Download PDF

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Publication number
HK1032534A1
HK1032534A1 HK01102229A HK01102229A HK1032534A1 HK 1032534 A1 HK1032534 A1 HK 1032534A1 HK 01102229 A HK01102229 A HK 01102229A HK 01102229 A HK01102229 A HK 01102229A HK 1032534 A1 HK1032534 A1 HK 1032534A1
Authority
HK
Hong Kong
Prior art keywords
ferrous
threonate
anemia
group
groups
Prior art date
Application number
HK01102229A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1031482A (en
Inventor
于凯
王志文
寇福平
Original Assignee
Juneng Industry Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juneng Industry Co., Ltd. filed Critical Juneng Industry Co., Ltd.
Publication of HK1031482A publication Critical patent/HK1031482A/xx
Publication of HK1032534A1 publication Critical patent/HK1032534A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10—Polyhydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A23L33/165—Complexes or chelates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK01102229A 1997-08-29 1998-08-28 L-threonate ferrous, as well as pharmaceutical composition and use for improving and treating human anemia thereof HK1032534A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN97116835 1997-08-29
CN97116835A CN1053653C (zh) 1997-08-29 1997-08-29 新l－苏糖酸衍生物
GB9805456.2 1998-03-13
PCT/CN1998/000174 WO1999011256A1 (en) 1997-08-29 1998-08-28 L-threonate ferrous, as well as pharmaceutical composition and use for improving and treating human anemia thereof

Publications (2)

Publication Number Publication Date
HK1031482A HK1031482A (en) 2001-06-15
HK1032534A1 true HK1032534A1 (en) 2001-07-27

Family

ID=5174140

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01102229A HK1032534A1 (en) 1997-08-29 1998-08-28 L-threonate ferrous, as well as pharmaceutical composition and use for improving and treating human anemia thereof

Country Status (9)

Country Link
US (1) US6313170B1 (https=)
EP (1) EP1038524B1 (https=)
JP (1) JP2001514219A (https=)
KR (1) KR100615537B1 (https=)
CN (1) CN1053653C (https=)
AU (1) AU8851298A (https=)
DE (1) DE69832722T2 (https=)
HK (1) HK1032534A1 (https=)
WO (1) WO1999011256A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1074762C (zh) 1998-08-18 2001-11-14 北京巨能亚太生命科学研究中心 L－苏糖酸铬盐、其制备方法及其应用
CN1196480C (zh) * 2001-07-03 2005-04-13 北京巨能亚太生命科学研究中心 L－苏糖酸钙在制备预防或治疗骨折的药物中的用途
JP4300753B2 (ja) * 2001-05-31 2009-07-22 味の素株式会社 貧血抑制剤及び食欲抑制剤
CN1197561C (zh) * 2001-07-03 2005-04-20 北京巨能亚太生命科学研究中心 L－苏糖酸钙在制备预防或治疗损及软骨的疾病的药物中的用途
US8142803B2 (en) 2007-03-22 2012-03-27 Magceutics, Inc. Magnesium compositions and uses thereof for neurological disorders
MX2009009939A (es) * 2007-03-22 2010-09-24 Magceutics Inc Composiciones de magnesio y usos de la misma.
EP2448413A4 (en) 2009-07-01 2013-02-13 Magceutics Inc SLOW RELEASE MAGNESIUM COMPOSITION AND USES THEREOF
CN104961636B (zh) * 2015-07-14 2016-08-31 启东东岳药业有限公司 L-苏糖酸镁合成方法
EP3347003A4 (en) 2015-09-11 2019-04-03 Neurocentria, Inc. THREATENER BINDINGS AND METHOD FOR USE THEREOF
CN105326855A (zh) * 2015-10-27 2016-02-17 南京大学 易吸收复合夹层式螯合镁钙片
CA3280511A1 (en) 2024-07-18 2026-03-01 Malian Biologicals Gmbh Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases and iron supplementation in neurodevelopmental or psychiatric disorder

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582914A (en) * 1985-01-31 1986-04-15 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors
US4611067A (en) * 1985-01-31 1986-09-09 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein
US5070085A (en) * 1987-04-10 1991-12-03 Oxycal Laboratories, Inc. Compositions and methods for administering therapeutically active compounds
WO1990012571A1 (en) * 1989-04-07 1990-11-01 Oxycal Laboratories, Inc. Compositions and methods for administering vitamin c
JPH0678247B2 (ja) * 1988-10-04 1994-10-05 大塚製薬株式会社 Ｎｍｒ造影用鉄含有製剤
JPH03291231A (ja) 1990-04-06 1991-12-20 Asahi Breweries Ltd 貧血改善剤
CN1060216A (zh) * 1990-09-25 1992-04-15 奥克斯可尔公司 含有治疗活性化合物的组合物及其施用方法
CN1228409A (zh) * 1998-03-05 1999-09-15 江西赣江制药有限责任公司 L－苏糖酸和苏糖酸盐(或酯)的制剂

Also Published As

Publication number Publication date
EP1038524A1 (en) 2000-09-27
DE69832722D1 (de) 2006-01-12
WO1999011256A1 (en) 1999-03-11
EP1038524B1 (en) 2005-12-07
KR100615537B1 (ko) 2006-08-25
DE69832722T2 (de) 2006-09-07
US6313170B1 (en) 2001-11-06
WO1999011256A8 (en) 1999-08-05
JP2001514219A (ja) 2001-09-11
CN1053653C (zh) 2000-06-21
KR20010023461A (ko) 2001-03-26
AU8851298A (en) 1999-03-22
CN1200366A (zh) 1998-12-02
EP1038524A4 (en) 2002-08-07

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090828