HK1031825A1 - Cd154 blockade therapy for therapeutic protein inhibitor syndrome. - Google Patents

Cd154 blockade therapy for therapeutic protein inhibitor syndrome.

Info

Publication number
HK1031825A1
HK1031825A1 HK01101074A HK01101074A HK1031825A1 HK 1031825 A1 HK1031825 A1 HK 1031825A1 HK 01101074 A HK01101074 A HK 01101074A HK 01101074 A HK01101074 A HK 01101074A HK 1031825 A1 HK1031825 A1 HK 1031825A1
Authority
HK
Hong Kong
Prior art keywords
protein inhibitor
therapeutic protein
blockade therapy
inhibitor syndrome
exogenous protein
Prior art date
Application number
HK01101074A
Other languages
English (en)
Inventor
Burt Adelman
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of HK1031825A1 publication Critical patent/HK1031825A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
HK01101074A 1997-06-20 2001-02-14 Cd154 blockade therapy for therapeutic protein inhibitor syndrome. HK1031825A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5027697P 1997-06-20 1997-06-20
PCT/US1998/012773 WO1998058672A1 (en) 1997-06-20 1998-06-19 Cd154 blockade therapy for therapeutic protein inhibitor syndrome

Publications (1)

Publication Number Publication Date
HK1031825A1 true HK1031825A1 (en) 2001-06-29

Family

ID=21964347

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01101074A HK1031825A1 (en) 1997-06-20 2001-02-14 Cd154 blockade therapy for therapeutic protein inhibitor syndrome.

Country Status (25)

Country Link
US (1) US20020119151A1 (ru)
EP (1) EP1034001B1 (ru)
JP (1) JP2002504910A (ru)
KR (1) KR100567998B1 (ru)
CN (2) CN1651071A (ru)
AT (1) ATE272408T1 (ru)
AU (1) AU733062B2 (ru)
BG (1) BG64436B1 (ru)
BR (1) BR9810755A (ru)
CA (1) CA2294138A1 (ru)
CZ (1) CZ295805B6 (ru)
DE (1) DE69825473T2 (ru)
EA (1) EA002512B1 (ru)
EE (1) EE9900587A (ru)
ES (1) ES2226152T3 (ru)
HK (1) HK1031825A1 (ru)
HU (1) HUP0002048A3 (ru)
IL (1) IL133305A0 (ru)
IS (1) IS2097B (ru)
NO (1) NO996274L (ru)
NZ (1) NZ502051A (ru)
PT (1) PT1034001E (ru)
SK (1) SK285962B6 (ru)
TR (1) TR199903141T2 (ru)
WO (1) WO1998058672A1 (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2343916A1 (en) * 1998-09-21 2000-03-30 Genetics Institute, Inc. Methods of downmodulating the immune response to therapeutic proteins
AU2001251612A1 (en) 2000-04-14 2001-10-30 Millennium Pharmaceuticals, Inc. Roles of jak/stat family members in tolerance induction
US6797263B2 (en) 2000-05-12 2004-09-28 Beth Israel Deaconess Medical Center, Inc. Compositions and methods for achieving immune suppression
AU2003223702A1 (en) * 2002-04-23 2003-11-10 Vddi Pharmaceuticals Inhibition of platelet aggregation
AU2004253868B2 (en) * 2003-06-13 2011-06-16 Biogen Ma Inc. Aglycosyl anti-CD154 (CD40 ligand) antibodies and uses thereof
CN1835976B (zh) * 2003-06-13 2012-06-13 比奥根艾迪克Ma公司 无糖基抗-cd154(cd40配体)抗体及其用途
AU2011224032B2 (en) * 2003-06-13 2013-01-31 Biogen Ma Inc. Aglycosyl Anti-CD154 (CD40 Ligand) Antibodies and Uses Thereof
DK1682178T3 (da) 2003-11-04 2010-10-04 Novartis Vaccines & Diagnostic Fremgangsmåder til terapi af cancere der udtrykker CD-40-antigenet
WO2006033702A2 (en) 2004-07-26 2006-03-30 Biogen Idec Ma Inc. Anti-cd154 antibodies
US20070286855A1 (en) * 2004-08-03 2007-12-13 Mayo Foundation For Medical Education And Research Improving treatments
US8333970B2 (en) 2005-05-18 2012-12-18 Novartis Ag Methods of monitoring the efficacy of anti-CD40 antibodies in treating a subject having an inflammatory or autoimmune disease
GEP20125628B (en) 2006-04-21 2012-09-10 Novartis Ag Pharmaceutical compositions containing antagonist anti-cd40 antibody
US9382327B2 (en) 2006-10-10 2016-07-05 Vaccinex, Inc. Anti-CD20 antibodies and methods of use
AR083847A1 (es) 2010-11-15 2013-03-27 Novartis Ag Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
US9447156B2 (en) 2011-05-17 2016-09-20 St. Jude Children's Research Hospital Methods and compositions for inhibiting neddylation of proteins
US20140004131A1 (en) 2012-05-04 2014-01-02 Novartis Ag Antibody formulation
KR20210095781A (ko) 2020-01-24 2021-08-03 주식회사 에이프릴바이오 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474771A (en) * 1991-11-15 1995-12-12 The Trustees Of Columbia University In The City Of New York Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same
KR100398819B1 (ko) * 1993-09-02 2004-02-05 트러스티스 오브 다트마우스 칼리지 gp39길항제를포함하는약제조성물
US5872154A (en) * 1995-02-24 1999-02-16 The Trustees Of The University Of Pennsylvania Method of reducing an immune response to a recombinant adenovirus
TR199902192T2 (xx) * 1997-01-10 1999-12-21 Biogen,Inc Anti-CDL40 bile�iklerinin tedavi ama�l� uygulama y�ntemleri

Also Published As

Publication number Publication date
IS2097B (is) 2006-04-12
PT1034001E (pt) 2004-12-31
US20020119151A1 (en) 2002-08-29
HUP0002048A2 (hu) 2000-10-28
WO1998058672A1 (en) 1998-12-30
SK285962B6 (sk) 2007-12-06
DE69825473D1 (de) 2004-09-09
BR9810755A (pt) 2000-08-15
TR199903141T2 (xx) 2000-09-21
EP1034001A1 (en) 2000-09-13
ES2226152T3 (es) 2005-03-16
CA2294138A1 (en) 1998-12-30
EE9900587A (et) 2000-08-15
BG64436B1 (en) 2005-02-28
EA200000059A1 (ru) 2000-08-28
EA002512B1 (ru) 2002-06-27
JP2002504910A (ja) 2002-02-12
AU733062B2 (en) 2001-05-03
NZ502051A (en) 2001-04-27
CZ458899A3 (cs) 2000-04-12
ATE272408T1 (de) 2004-08-15
EP1034001B1 (en) 2004-08-04
BG104092A (en) 2000-10-31
CZ295805B6 (cs) 2005-11-16
CN1261285A (zh) 2000-07-26
KR20010013964A (ko) 2001-02-26
AU8153698A (en) 1999-01-04
NO996274D0 (no) 1999-12-17
KR100567998B1 (ko) 2006-04-07
IS5274A (is) 1999-11-26
DE69825473T2 (de) 2005-08-04
CN1651071A (zh) 2005-08-10
SK180399A3 (en) 2000-06-12
IL133305A0 (en) 2001-04-30
NO996274L (no) 2000-02-18
HUP0002048A3 (en) 2002-09-30

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Legal Events

Date Code Title Description
AM Amended specification (according sect 146 of patent law)

Free format text: CORRECTION OF THE NAME AND ADDRESS OF PROPRIETOR FROM BIOGEN IDEC MA, INC, 14 CAMBRIDGE CENTER, CAMBRIDGE, MASSACHUSETTS 02142, UNITED STATES/UNITED STATES OF AMERICA TO BIOGEN IDEC MA INC., 14 CAMBRIDGE CENTER, CAMBRIDGE, MA 02142, UNITED STATES/UNITED STATES OF AMERICA.

Effective date: 20060331

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090619