HK1029996A1 - Process for the preparation of n-[5-(diphenylphosphinoylmethyl)-4-(4-fluorphenyl)-6-isopropylpyrimidin-2-yl]-n-methylmethansulfonamide - Google Patents
Process for the preparation of n-[5-(diphenylphosphinoylmethyl)-4-(4-fluorphenyl)-6-isopropylpyrimidin-2-yl]-n-methylmethansulfonamideInfo
- Publication number
- HK1029996A1 HK1029996A1 HK01100875A HK01100875A HK1029996A1 HK 1029996 A1 HK1029996 A1 HK 1029996A1 HK 01100875 A HK01100875 A HK 01100875A HK 01100875 A HK01100875 A HK 01100875A HK 1029996 A1 HK1029996 A1 HK 1029996A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diphenylphosphinoylmethyl
- isopropylpyrimidin
- preparation
- fluorophenyl
- methylmethansulfonamide
- Prior art date
Links
- CVRDGWDBQZPJJI-UHFFFAOYSA-N n-[5-(diphenylphosphorylmethyl)-4-(4-fluorophenyl)-6-propan-2-ylpyrimidin-2-yl]-n-methylmethanesulfonamide Chemical compound C=1C=CC=CC=1P(=O)(C=1C=CC=CC=1)CC=1C(C(C)C)=NC(N(C)S(C)(=O)=O)=NC=1C1=CC=C(F)C=C1 CVRDGWDBQZPJJI-UHFFFAOYSA-N 0.000 abstract 2
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
- XGRJZXREYAXTGV-UHFFFAOYSA-N chlorodiphenylphosphine Chemical compound C=1C=CC=CC=1P(Cl)C1=CC=CC=C1 XGRJZXREYAXTGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99104786 | 1999-03-10 | ||
| EP99104785 | 1999-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1029996A1 true HK1029996A1 (en) | 2001-04-20 |
Family
ID=26152921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK01100875A HK1029996A1 (en) | 1999-03-10 | 2001-02-08 | Process for the preparation of n-[5-(diphenylphosphinoylmethyl)-4-(4-fluorphenyl)-6-isopropylpyrimidin-2-yl]-n-methylmethansulfonamide |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1035127B1 (zh) |
| JP (1) | JP4438167B2 (zh) |
| KR (1) | KR100586664B1 (zh) |
| CN (1) | CN1126755C (zh) |
| AT (1) | ATE251633T1 (zh) |
| CA (1) | CA2300243C (zh) |
| CZ (1) | CZ298235B6 (zh) |
| DE (1) | DE50003959D1 (zh) |
| DK (1) | DK1035127T3 (zh) |
| ES (1) | ES2208167T3 (zh) |
| HK (1) | HK1029996A1 (zh) |
| HU (1) | HU224967B1 (zh) |
| NO (1) | NO324982B1 (zh) |
| PL (1) | PL195166B1 (zh) |
| PT (1) | PT1035127E (zh) |
| SK (1) | SK284027B6 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0311195A (pt) * | 2002-05-21 | 2005-02-22 | Ranbaxy Lab Ltd | Processo de preparação de rosuvastatina |
| US7341743B2 (en) | 2004-10-28 | 2008-03-11 | Revlon Consumer Products Corporation | Color cosmetic compositions |
| US8653265B2 (en) | 2008-05-27 | 2014-02-18 | Changzhou Pharmaceutical Factory | Preparation method of rosuvastatin calcium and its intermediates |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
-
2000
- 2000-03-07 CZ CZ20000837A patent/CZ298235B6/cs not_active IP Right Cessation
- 2000-03-07 SK SK332-2000A patent/SK284027B6/sk not_active IP Right Cessation
- 2000-03-09 DK DK00105011T patent/DK1035127T3/da active
- 2000-03-09 NO NO20001228A patent/NO324982B1/no not_active IP Right Cessation
- 2000-03-09 AT AT00105011T patent/ATE251633T1/de active
- 2000-03-09 CA CA002300243A patent/CA2300243C/en not_active Expired - Lifetime
- 2000-03-09 EP EP00105011A patent/EP1035127B1/de not_active Expired - Lifetime
- 2000-03-09 PT PT00105011T patent/PT1035127E/pt unknown
- 2000-03-09 DE DE50003959T patent/DE50003959D1/de not_active Expired - Lifetime
- 2000-03-09 ES ES00105011T patent/ES2208167T3/es not_active Expired - Lifetime
- 2000-03-10 PL PL338944A patent/PL195166B1/pl unknown
- 2000-03-10 HU HU0001127A patent/HU224967B1/hu unknown
- 2000-03-10 CN CN00103783A patent/CN1126755C/zh not_active Expired - Lifetime
- 2000-03-10 KR KR1020000012002A patent/KR100586664B1/ko not_active IP Right Cessation
- 2000-03-10 JP JP2000066084A patent/JP4438167B2/ja not_active Expired - Lifetime
-
2001
- 2001-02-08 HK HK01100875A patent/HK1029996A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2300243A1 (en) | 2000-09-10 |
| NO324982B1 (no) | 2008-01-14 |
| KR20010006773A (ko) | 2001-01-26 |
| CA2300243C (en) | 2009-12-29 |
| PL338944A1 (en) | 2000-09-11 |
| HU224967B1 (en) | 2006-04-28 |
| CN1126755C (zh) | 2003-11-05 |
| EP1035127A1 (de) | 2000-09-13 |
| KR100586664B1 (ko) | 2006-06-07 |
| JP4438167B2 (ja) | 2010-03-24 |
| HUP0001127A2 (hu) | 2001-06-28 |
| SK284027B6 (sk) | 2004-08-03 |
| EP1035127B1 (de) | 2003-10-08 |
| PL195166B1 (pl) | 2007-08-31 |
| PT1035127E (pt) | 2004-02-27 |
| CZ2000837A3 (cs) | 2000-10-11 |
| HUP0001127A3 (en) | 2003-07-28 |
| CN1272499A (zh) | 2000-11-08 |
| DK1035127T3 (da) | 2003-11-03 |
| DE50003959D1 (de) | 2003-11-13 |
| NO20001228L (no) | 2000-09-11 |
| JP2000309595A (ja) | 2000-11-07 |
| CZ298235B6 (cs) | 2007-08-01 |
| SK3322000A3 (en) | 2000-10-09 |
| ES2208167T3 (es) | 2004-06-16 |
| ATE251633T1 (de) | 2003-10-15 |
| HU0001127D0 (en) | 2000-05-28 |
| NO20001228D0 (no) | 2000-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force |