HK1026691A1 - Substituted benzimidazoles and their use for treating retroviral infection - Google Patents

Substituted benzimidazoles and their use for treating retroviral infection

Info

Publication number
HK1026691A1
HK1026691A1 HK00104566A HK00104566A HK1026691A1 HK 1026691 A1 HK1026691 A1 HK 1026691A1 HK 00104566 A HK00104566 A HK 00104566A HK 00104566 A HK00104566 A HK 00104566A HK 1026691 A1 HK1026691 A1 HK 1026691A1
Authority
HK
Hong Kong
Prior art keywords
retroviral infection
substituted benzimidazoles
treating retroviral
treating
methods
Prior art date
Application number
HK00104566A
Other languages
English (en)
Inventor
Christine C Dykstra
David Boykin
Richard R Tidwell
Original Assignee
Univ North Carolina
Univ Auburn
Univ Georgia State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina, Univ Auburn, Univ Georgia State filed Critical Univ North Carolina
Publication of HK1026691A1 publication Critical patent/HK1026691A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK00104566A 1997-02-28 2000-07-24 Substituted benzimidazoles and their use for treating retroviral infection HK1026691A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/808,321 US5935982A (en) 1997-02-28 1997-02-28 Methods of treating retroviral infection and compounds useful therefor
PCT/US1998/003830 WO1998038170A1 (fr) 1997-02-28 1998-02-27 Benzimidazoles substitues et leur utilisation dans le traitement d'une infection retrovirale

Publications (1)

Publication Number Publication Date
HK1026691A1 true HK1026691A1 (en) 2000-12-22

Family

ID=25198455

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00104566A HK1026691A1 (en) 1997-02-28 2000-07-24 Substituted benzimidazoles and their use for treating retroviral infection

Country Status (9)

Country Link
US (1) US5935982A (fr)
EP (1) EP0973750B1 (fr)
JP (1) JP2002513404A (fr)
AT (1) ATE264846T1 (fr)
AU (1) AU738975B2 (fr)
CA (1) CA2282552A1 (fr)
DE (1) DE69823344T2 (fr)
HK (1) HK1026691A1 (fr)
WO (1) WO1998038170A1 (fr)

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US20020124843A1 (en) * 2001-02-01 2002-09-12 Skiba Jeffry B. Eye medication delivery system
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EP1545510A4 (fr) * 2002-08-07 2006-11-15 Idenix Cayman Ltd Phenylindoles substitues de traitement du vih
ATE432306T1 (de) * 2003-03-07 2009-06-15 Merck Patent Gmbh Fluorene und arylgruppen enthaltende mono-, oligo-und polymere
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US8188132B2 (en) * 2009-02-17 2012-05-29 Enanta Pharmaceuticals, Inc. Linked dibenzimidazole derivatives
US8242156B2 (en) * 2009-02-17 2012-08-14 Enanta Pharmaceuticals, Inc. Linked dibenzimidazole derivatives
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CA2758484A1 (fr) * 2009-04-15 2010-10-21 David A. Degoey Composes antiviraux
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US8772505B2 (en) 2009-05-29 2014-07-08 Merck Sharp & Dohme Corp. Antiviral compounds composed of three aligned aryl moieties to treat diseases such as hepatitis C
US8980920B2 (en) 2009-05-29 2015-03-17 Merck Sharp & Dohme Corp. Antiviral compounds of three linked aryl moieties to treat diseases such as hepatitis C
TW201519891A (zh) * 2009-06-11 2015-06-01 Abbott Lab 抗病毒化合物
US8937150B2 (en) 2009-06-11 2015-01-20 Abbvie Inc. Anti-viral compounds
US9394279B2 (en) 2009-06-11 2016-07-19 Abbvie Inc. Anti-viral compounds
US8716454B2 (en) 2009-06-11 2014-05-06 Abbvie Inc. Solid compositions
US8221737B2 (en) 2009-06-16 2012-07-17 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
WO2010148006A1 (fr) * 2009-06-16 2010-12-23 Enanta Pharmaceuticals, Inc. Inhibiteurs du virus de l'hépatite c
US8609648B2 (en) 2009-07-02 2013-12-17 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
US9156818B2 (en) * 2009-09-11 2015-10-13 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
US8703938B2 (en) * 2009-09-11 2014-04-22 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
US8927709B2 (en) * 2009-09-11 2015-01-06 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
US8815928B2 (en) 2009-09-11 2014-08-26 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
US8759332B2 (en) * 2009-09-11 2014-06-24 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
US8822700B2 (en) * 2009-09-11 2014-09-02 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
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US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
JP5669984B2 (ja) 2011-05-18 2015-02-18 エナンタ ファーマシューティカルズ インコーポレイテッド ５−アザスピロ［２．４］ヘプタン−６−カルボン酸およびその誘導体の製造方法
US9034832B2 (en) 2011-12-29 2015-05-19 Abbvie Inc. Solid compositions
CN104364250B (zh) * 2012-04-13 2017-05-31 株式会社Lg化学 新的含氮杂环化合物及使用其的有机电子器件
US11484534B2 (en) 2013-03-14 2022-11-01 Abbvie Inc. Methods for treating HCV
EP3089757A1 (fr) 2014-01-03 2016-11-09 AbbVie Inc. Formes galéniques antivirales solides
GB201506660D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
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WO2017223260A1 (fr) 2016-06-23 2017-12-28 Albert Einstein College Of Medicine, Inc. Inhibiteurs de pu.1
CN109553608B (zh) * 2017-09-26 2020-12-08 北京大学 一类五元六元杂环化合物及其制备方法和治疗肿瘤的用途
CN113264925A (zh) * 2020-02-14 2021-08-17 上海美悦生物科技发展有限公司 一种杂环化合物及其制备方法和用途

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Also Published As

Publication number Publication date
AU6670798A (en) 1998-09-18
DE69823344T2 (de) 2005-05-12
WO1998038170A1 (fr) 1998-09-03
US5935982A (en) 1999-08-10
ATE264846T1 (de) 2004-05-15
DE69823344D1 (de) 2004-05-27
CA2282552A1 (fr) 1998-09-03
JP2002513404A (ja) 2002-05-08
EP0973750B1 (fr) 2004-04-21
AU738975B2 (en) 2001-10-04
EP0973750A1 (fr) 2000-01-26

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080227