HK1020258A1 - 5 alpha-reductase inhibitory preparation for oral administration, process for producing the same, and use thereof - Google Patents

5 alpha-reductase inhibitory preparation for oral administration, process for producing the same, and use thereof

Info

Publication number
HK1020258A1
HK1020258A1 HK99105393A HK99105393A HK1020258A1 HK 1020258 A1 HK1020258 A1 HK 1020258A1 HK 99105393 A HK99105393 A HK 99105393A HK 99105393 A HK99105393 A HK 99105393A HK 1020258 A1 HK1020258 A1 HK 1020258A1
Authority
HK
Hong Kong
Prior art keywords
alpha
oral administration
producing
same
reductase inhibitory
Prior art date
Application number
HK99105393A
Other languages
English (en)
Inventor
Fusao Usui
Yuko Ohuchi
Akira Kusai
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HK1020258A1 publication Critical patent/HK1020258A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK99105393A 1996-02-05 1999-11-22 5 alpha-reductase inhibitory preparation for oral administration, process for producing the same, and use thereof HK1020258A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1871896 1996-02-05
PCT/JP1997/000273 WO1997027875A1 (fr) 1996-02-05 1997-02-04 PREPARATION INHIBITRICE DE LA 5α-REDUCTASE ADMINISTRABLE PAR VOIE ORALE, PROCEDE DE PRODUCTION ET UTILISATION

Publications (1)

Publication Number Publication Date
HK1020258A1 true HK1020258A1 (en) 2000-04-07

Family

ID=11979447

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99105393A HK1020258A1 (en) 1996-02-05 1999-11-22 5 alpha-reductase inhibitory preparation for oral administration, process for producing the same, and use thereof

Country Status (18)

Country Link
US (1) US20020015732A1 (de)
EP (1) EP0923942B1 (de)
KR (1) KR19990082277A (de)
CN (1) CN1215339A (de)
AT (1) ATE208631T1 (de)
AU (1) AU709146B2 (de)
CZ (1) CZ289856B6 (de)
DE (1) DE69708307T2 (de)
DK (1) DK0923942T3 (de)
ES (1) ES2165017T3 (de)
HK (1) HK1020258A1 (de)
HU (1) HUP9901870A3 (de)
MX (1) MX9806292A (de)
NO (1) NO983580L (de)
NZ (1) NZ326897A (de)
PT (1) PT923942E (de)
RU (1) RU2154467C2 (de)
WO (1) WO1997027875A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ337048A (en) * 1997-02-26 2000-10-27 Sankyo Co Use of N-[1-methyl-(substituted phenyl)ethyl]-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide derivatives to treat prostate cancer
ATE262337T1 (de) * 1997-07-29 2004-04-15 Sankyo Co Azasteroidverbindung zur behandlung von alopezie, hirsutismus und seborrhoe
CN110628735B (zh) * 2019-04-23 2022-04-08 天津科技大学 一种5α-还原酶突变体,基因工程菌及其在高效催化5α-AD生产中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403359D0 (en) * 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
ZA851426B (en) * 1984-02-27 1986-10-29 Merck & Co Inc 17 beta-n-monosubstituted carbamoyl-4-aza-5 alpha-androst-1-en-3-ones as 5 alpha reductase inhibitors
IE76452B1 (en) * 1990-10-29 1997-10-22 Sankyo Co Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use
JPH06293793A (ja) * 1993-02-10 1994-10-21 Sankyo Co Ltd ステロイド−17−アミド類の製造法

Also Published As

Publication number Publication date
EP0923942A1 (de) 1999-06-23
CZ234298A3 (cs) 1998-11-11
WO1997027875A1 (fr) 1997-08-07
US20020015732A1 (en) 2002-02-07
AU709146B2 (en) 1999-08-19
CZ289856B6 (cs) 2002-04-17
DK0923942T3 (da) 2001-12-17
HUP9901870A3 (en) 1999-11-29
DE69708307T2 (de) 2002-08-14
ES2165017T3 (es) 2002-03-01
MX9806292A (es) 1998-11-30
NO983580D0 (no) 1998-08-04
NZ326897A (en) 1999-08-30
EP0923942A4 (de) 1999-06-23
PT923942E (pt) 2002-03-28
HUP9901870A2 (hu) 1999-09-28
KR19990082277A (ko) 1999-11-25
CN1215339A (zh) 1999-04-28
RU2154467C2 (ru) 2000-08-20
DE69708307D1 (de) 2001-12-20
EP0923942B1 (de) 2001-11-14
NO983580L (no) 1998-10-02
AU1558997A (en) 1997-08-22
ATE208631T1 (de) 2001-11-15

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060204