HK101996A - Tricyclic compounds processes for their preparation and pharmaceutical compositions comprising them - Google Patents
Tricyclic compounds processes for their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- HK101996A HK101996A HK101996A HK101996A HK101996A HK 101996 A HK101996 A HK 101996A HK 101996 A HK101996 A HK 101996A HK 101996 A HK101996 A HK 101996A HK 101996 A HK101996 A HK 101996A
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparation
- pharmaceutical compositions
- tricyclic compounds
- compounds processes
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888821257A GB8821257D0 (en) | 1988-09-09 | 1988-09-09 | Tricyclic compounds |
| GB888829265A GB8829265D0 (en) | 1988-12-15 | 1988-12-15 | Tricyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK101996A true HK101996A (en) | 1996-06-21 |
Family
ID=26294376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK101996A HK101996A (en) | 1988-09-09 | 1996-06-13 | Tricyclic compounds processes for their preparation and pharmaceutical compositions comprising them |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4981847A (de) |
| EP (1) | EP0360079B1 (de) |
| JP (3) | JPH0665673B2 (de) |
| KR (1) | KR900004737A (de) |
| CN (1) | CN1022187C (de) |
| AU (1) | AU628370B2 (de) |
| DE (1) | DE68912858T2 (de) |
| DK (1) | DK444789A (de) |
| ES (1) | ES2061848T3 (de) |
| FI (1) | FI92401C (de) |
| HK (1) | HK101996A (de) |
| HU (2) | HUT54152A (de) |
| IE (1) | IE62916B1 (de) |
| IL (1) | IL91361A (de) |
| NO (1) | NO171913C (de) |
| PH (1) | PH27358A (de) |
| PT (1) | PT91664B (de) |
| RU (1) | RU2007406C1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2630440B1 (fr) * | 1988-04-25 | 1991-09-20 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique |
| IL91361A (en) * | 1988-09-09 | 1994-10-07 | Fujisawa Pharmaceutical Co | Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them |
| US5248679A (en) * | 1988-09-09 | 1993-09-28 | Fujisawa Pharmaceutical Co., Ltd. | Tricyclic compounds |
| IL93401A (en) * | 1989-03-08 | 1994-08-26 | Kali Chemie Pharma Gmbh | H1 - Indole - 2 - Carboxylic acid 1, 7 - Consolidated N -) 1, 4 - Benzodiazepine - 3 - Il (amides, their preparation and drugs containing them |
| FR2652352A1 (fr) * | 1989-09-28 | 1991-03-29 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique. |
| GB9018601D0 (en) * | 1990-08-24 | 1990-10-10 | Fujisawa Pharmaceutical Co | Tricyclic compounds |
| CA2056809A1 (en) * | 1990-12-07 | 1992-06-08 | Mark G. Bock | Benzodiazepine analogs |
| EP0572235A3 (en) * | 1992-05-28 | 1994-06-01 | Tanabe Seiyaku Co | Beta-carboline derivatives with anticholecystoquinine activity |
| GB2271354A (en) * | 1992-10-07 | 1994-04-13 | Merck Sharp & Dohme | Tricyclic derivatives of benzodiazepines |
| AU6045994A (en) * | 1993-03-03 | 1994-09-26 | Fujisawa Pharmaceutical Co., Ltd. | Optical isomerization inhibitor |
| ATE211464T1 (de) * | 1993-11-26 | 2002-01-15 | Tanabe Seiyaku Co | 2-oxoindolin-derivate als cholecystokinin rezeptor antagonisten |
| WO1996004254A2 (en) * | 1994-07-29 | 1996-02-15 | Fujisawa Pharmaceutical Co., Ltd. | Benzodiazepine derivatives |
| ZA957201B (en) * | 1994-08-30 | 1996-04-01 | Fujisawa Pharmaceutical Co | Liposome preparation |
| FR2725719B1 (fr) * | 1994-10-14 | 1996-12-06 | Jouveinal Inst Rech | Diazepino-indoles inhibiteurs de phosphodiesterases iv |
| US5716958A (en) | 1994-10-27 | 1998-02-10 | Tobishi Pharmaceutical Co., Ltd. | Amino acid derivative having anti-CCK activity |
| AUPO284396A0 (en) | 1996-10-08 | 1996-10-31 | Fujisawa Pharmaceutical Co., Ltd. | Benzodiazepine derivatives |
| FR2776660B1 (fr) * | 1998-03-27 | 2000-05-12 | Parke Davis | Diazepino-indoles de phosphodiesterases iv |
| EP2897942B1 (de) | 2012-09-21 | 2016-08-31 | Bristol-Myers Squibb Company | Fluoralkyl- und fluorocycloalkyl-1,4-benzodiazepinonverbindungen als notch-inhibitoren |
| CN104797584A (zh) | 2012-09-21 | 2015-07-22 | 百时美施贵宝公司 | 作为notch抑制剂的三环杂环化合物 |
| EP2897944B1 (de) | 2012-09-21 | 2016-10-26 | Bristol-Myers Squibb Company | Substituierte 1,5-benzodiazepinon-verbindungen |
| EP2897946B1 (de) | 2012-09-21 | 2016-11-16 | Bristol-Myers Squibb Company | N-substituierte bis(fluoralkyl)-1,4-benzodiazepinonverbindungen |
| CN104968648A (zh) | 2012-09-21 | 2015-10-07 | 百时美施贵宝公司 | 1,4-苯并二氮杂*酮化合物的前药 |
| JP2015534554A (ja) | 2012-09-21 | 2015-12-03 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | アルキル，フルオロアルキル−１，４−ベンゾジアゼピノン化合物 |
| WO2014047392A1 (en) | 2012-09-21 | 2014-03-27 | Bristol-Myers Squibb Company | Fluoroalkyl-1,4-benzodiazepinone compounds |
| JP2015529250A (ja) | 2012-09-21 | 2015-10-05 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | フルオロアルキルジベンゾジアゼピノン化合物 |
| US9492469B2 (en) | 2013-04-04 | 2016-11-15 | Bristol-Myers Squibb Company | Combination therapy for the treatment of proliferative diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3651083A (en) * | 1969-11-03 | 1972-03-21 | Upjohn Co | Tetra- and hexahydro-phenylpyrrolo benzodiazepines and intermediates |
| AU2733371A (en) * | 1970-04-14 | 1972-10-12 | A. H. Robins Company, Incorporated | 5, 7-DISUBSTITUTED-l, 9-ALKYLENE-l, 4-BENZODIAZEPIN-2 ONES |
| US3794646A (en) * | 1970-04-14 | 1974-02-26 | Robins Co Inc A H | 5,7-disubstituted-1,9-tetramethylene-1,4-benzodiazepin-2-ones |
| CA1332410C (en) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
| US4735941A (en) * | 1986-12-23 | 1988-04-05 | Merck & Co., Inc. | 1,4-benzodiazepines with 5- and 6-membered heterocyclic rings, useful as gastrointestinal and CNS agents |
| FR2630440B1 (fr) * | 1988-04-25 | 1991-09-20 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique |
| IL91361A (en) * | 1988-09-09 | 1994-10-07 | Fujisawa Pharmaceutical Co | Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them |
-
1989
- 1989-08-20 IL IL9136189A patent/IL91361A/en not_active IP Right Cessation
- 1989-08-21 PH PH39119A patent/PH27358A/en unknown
- 1989-08-21 US US07/396,124 patent/US4981847A/en not_active Expired - Lifetime
- 1989-08-25 AU AU40257/89A patent/AU628370B2/en not_active Ceased
- 1989-09-04 IE IE284089A patent/IE62916B1/en not_active IP Right Cessation
- 1989-09-05 FI FI894169A patent/FI92401C/fi not_active IP Right Cessation
- 1989-09-06 JP JP1232643A patent/JPH0665673B2/ja not_active Expired - Fee Related
- 1989-09-07 ES ES89116504T patent/ES2061848T3/es not_active Expired - Lifetime
- 1989-09-07 EP EP89116504A patent/EP0360079B1/de not_active Expired - Lifetime
- 1989-09-07 DE DE68912858T patent/DE68912858T2/de not_active Expired - Lifetime
- 1989-09-08 PT PT91664A patent/PT91664B/pt not_active IP Right Cessation
- 1989-09-08 NO NO893616A patent/NO171913C/no unknown
- 1989-09-08 RU SU894742037A patent/RU2007406C1/ru active
- 1989-09-08 KR KR1019890013125A patent/KR900004737A/ko not_active Application Discontinuation
- 1989-09-08 HU HU894800A patent/HUT54152A/hu unknown
- 1989-09-08 CN CN89107000A patent/CN1022187C/zh not_active Expired - Fee Related
- 1989-09-08 DK DK444789A patent/DK444789A/da not_active Application Discontinuation
-
1990
- 1990-11-15 US US07/612,955 patent/US5155101A/en not_active Expired - Fee Related
-
1994
- 1994-01-27 JP JP6007480A patent/JP2848230B2/ja not_active Expired - Lifetime
- 1994-01-27 JP JP6007479A patent/JPH0741480A/ja active Pending
-
1995
- 1995-06-22 HU HU95P/P00370P patent/HU211264A9/hu unknown
-
1996
- 1996-06-13 HK HK101996A patent/HK101996A/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |