HK1016169A1 - Hydrolysis-promoting taxane hydrophobic derivatives - Google Patents

Hydrolysis-promoting taxane hydrophobic derivatives

Info

Publication number
HK1016169A1
HK1016169A1 HK99101119A HK99101119A HK1016169A1 HK 1016169 A1 HK1016169 A1 HK 1016169A1 HK 99101119 A HK99101119 A HK 99101119A HK 99101119 A HK99101119 A HK 99101119A HK 1016169 A1 HK1016169 A1 HK 1016169A1
Authority
HK
Hong Kong
Prior art keywords
taxane
hydrolysis
promoting
hydrocarbon
hydrophobic derivatives
Prior art date
Application number
HK99101119A
Other languages
English (en)
Inventor
Eric Mayhew
Shaukat Ali
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of HK1016169A1 publication Critical patent/HK1016169A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
HK99101119A 1995-09-12 1999-03-18 Hydrolysis-promoting taxane hydrophobic derivatives HK1016169A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12
PCT/US1996/014631 WO1997010234A1 (en) 1995-09-12 1996-09-12 Hydrolysis-promoting taxane hydrophobic derivatives

Publications (1)

Publication Number Publication Date
HK1016169A1 true HK1016169A1 (en) 1999-10-29

Family

ID=21706522

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99101119A HK1016169A1 (en) 1995-09-12 1999-03-18 Hydrolysis-promoting taxane hydrophobic derivatives

Country Status (22)

Country Link
US (1) US5703117A (de)
EP (1) EP0902783B1 (de)
JP (1) JP4192208B2 (de)
KR (1) KR100401220B1 (de)
CN (1) CN1100770C (de)
AT (2) ATE216377T1 (de)
CA (1) CA2231750C (de)
CZ (1) CZ288562B6 (de)
DE (2) DE69635428T2 (de)
DK (2) DK1229030T3 (de)
ES (2) ES2179208T3 (de)
HK (1) HK1016169A1 (de)
HU (1) HU226325B1 (de)
IL (1) IL123595A (de)
MX (1) MX9801871A (de)
NO (1) NO319521B1 (de)
NZ (1) NZ318300A (de)
PL (1) PL187738B1 (de)
PT (1) PT902783E (de)
SK (1) SK283199B6 (de)
TR (1) TR199800443T1 (de)
WO (1) WO1997010234A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
EP1964557B1 (de) * 1997-11-10 2013-01-02 Memorial Sloan-Kettering Cancer Center Verfahren zur Herstellung von Arsentrioxidformulierungen
US6500461B2 (en) * 1998-05-20 2002-12-31 The Liposome Company Particulate formulations
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
JP2002534461A (ja) * 1999-01-12 2002-10-15 クアナム メディカル コーポレイション 水不溶性のパクリタキセル誘導体の投与のための組成物および方法
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
AU7007001A (en) 2000-06-22 2002-01-02 Nitromed Inc Nitrosated and nitrosylated taxanes, compositions and methods of use
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
DE60137229D1 (de) * 2001-10-22 2009-02-12 Viroblock Sa Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen
WO2003045326A2 (en) * 2001-11-26 2003-06-05 Supergen, Inc Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
DE60335279D1 (de) * 2002-06-26 2011-01-20 Medigene Ag Neues verfahren zur stabilisierung von diagnostischen und therapeutischen verbindungen in einem kationischen trägersystem
BRPI0407096A (pt) 2003-02-03 2006-01-24 Neopharm Inc Taxano encapsulado em lipossomo estável, estéril e filtrável e outros fármacos antineoplásicos
CN103143069B (zh) * 2005-02-18 2016-05-04 阿布拉西斯生物科学公司 用于整合入医疗装置的疏水性改善的药物
JP2008535927A (ja) 2005-04-12 2008-09-04 ウィスコンシン アルムニ リサーチ ファンデイション ポリマー及びパッセンジャー薬のミセル組成物
KR20150136137A (ko) * 2008-04-10 2015-12-04 아브락시스 바이오사이언스, 엘엘씨 소수성 탁산 유도체의 조성물 및 그의 용도
WO2009126401A1 (en) * 2008-04-10 2009-10-15 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
WO2011038278A2 (en) 2009-09-25 2011-03-31 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
EP1251127B1 (de) * 1992-12-23 2005-11-09 Bristol-Myers Squibb Company Seitenkette tragende Taxanen und deren Zwischenprodukten
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State History of C-10 Texan and pharmaceuticals containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
DE69620802T2 (de) 2002-10-10
CN1100770C (zh) 2003-02-05
ATE309235T1 (de) 2005-11-15
SK33498A3 (en) 1998-08-05
CA2231750C (en) 2006-07-11
US5703117A (en) 1997-12-30
JP4192208B2 (ja) 2008-12-10
KR19990044409A (ko) 1999-06-25
ES2252347T3 (es) 2006-05-16
EP0902783A1 (de) 1999-03-24
CA2231750A1 (en) 1997-03-20
DK0902783T3 (da) 2002-07-22
NO981071D0 (no) 1998-03-11
TR199800443T1 (xx) 1998-06-22
AU706290B2 (en) 1999-06-10
DE69635428D1 (de) 2005-12-15
AU6975696A (en) 1997-04-01
WO1997010234A1 (en) 1997-03-20
PL187738B1 (pl) 2004-09-30
ES2179208T3 (es) 2003-01-16
NO319521B1 (no) 2005-08-22
MX9801871A (es) 1998-05-31
IL123595A0 (en) 1998-10-30
ATE216377T1 (de) 2002-05-15
SK283199B6 (sk) 2003-03-04
CZ71198A3 (cs) 1998-07-15
CZ288562B6 (cs) 2001-07-11
DK1229030T3 (da) 2006-02-13
NO981071L (no) 1998-05-12
PL325477A1 (en) 1998-07-20
DE69635428T2 (de) 2006-06-14
PT902783E (pt) 2002-09-30
EP0902783A4 (de) 1999-03-24
DE69620802D1 (de) 2002-05-23
HUP9901433A3 (en) 2001-05-28
CN1202166A (zh) 1998-12-16
HU226325B1 (en) 2008-08-28
HUP9901433A2 (hu) 2001-04-28
NZ318300A (en) 1999-08-30
JP2001519755A (ja) 2001-10-23
IL123595A (en) 2000-10-31
EP0902783B1 (de) 2002-04-17
KR100401220B1 (ko) 2004-03-20

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080911