HK1013814A1 - Oxidized carotenoids retinoids and related conjugated polyenes and derived fractions and compounds useful as cell-differentiation inducers cytostatic agent - Google Patents

Oxidized carotenoids retinoids and related conjugated polyenes and derived fractions and compounds useful as cell-differentiation inducers cytostatic agent

Info

Publication number
HK1013814A1
HK1013814A1 HK98115319A HK98115319A HK1013814A1 HK 1013814 A1 HK1013814 A1 HK 1013814A1 HK 98115319 A HK98115319 A HK 98115319A HK 98115319 A HK98115319 A HK 98115319A HK 1013814 A1 HK1013814 A1 HK 1013814A1
Authority
HK
Hong Kong
Prior art keywords
carotene
vitamin
oxidized
beta
cell
Prior art date
Application number
HK98115319A
Other languages
English (en)
Inventor
Graham Burton
Janusz Daroszewski
Jenny Phipps
Prabhat Arya
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of HK1013814A1 publication Critical patent/HK1013814A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK98115319A 1994-08-10 1998-12-24 Oxidized carotenoids retinoids and related conjugated polyenes and derived fractions and compounds useful as cell-differentiation inducers cytostatic agent HK1013814A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/288,315 US5475006A (en) 1994-08-10 1994-08-10 Extensively oxidized derivatives of carotenoids, retinoids and related conjugated polyenes useful as non-toxic cell-differentiation inducers, anti-proliferative agents, and anti-tumor agents
PCT/CA1995/000484 WO1996005160A1 (en) 1994-08-10 1995-08-10 Oxidized carotenoids, retinoids and related conjugated polyenes, and derived fractions and compounds useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents

Publications (1)

Publication Number Publication Date
HK1013814A1 true HK1013814A1 (en) 1999-09-10

Family

ID=23106590

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98115319A HK1013814A1 (en) 1994-08-10 1998-12-24 Oxidized carotenoids retinoids and related conjugated polyenes and derived fractions and compounds useful as cell-differentiation inducers cytostatic agent

Country Status (19)

Country Link
US (1) US5475006A (zh)
EP (1) EP0722431B1 (zh)
JP (1) JP3983800B2 (zh)
KR (1) KR100404724B1 (zh)
CN (1) CN1131939A (zh)
AT (1) ATE201394T1 (zh)
AU (1) AU704640B2 (zh)
CA (1) CA2171625C (zh)
CZ (1) CZ103896A3 (zh)
DE (1) DE69521020T2 (zh)
ES (1) ES2160172T3 (zh)
FI (1) FI961544A (zh)
GB (1) GB2297325B (zh)
HK (1) HK1013814A1 (zh)
MX (1) MX9601175A (zh)
NZ (1) NZ290769A (zh)
PL (1) PL184296B1 (zh)
PT (1) PT722431E (zh)
WO (1) WO1996005160A1 (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432711B1 (en) * 1993-11-03 2002-08-13 Diacrin, Inc. Embryonic stem cells capable of differentiating into desired cell lines
US7132458B2 (en) * 1994-08-10 2006-11-07 Chemaphor Inc. Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
US20040228871A1 (en) * 1999-06-03 2004-11-18 Tayyaba Hasan Treatment and analysis of proliferative disorders
IL135335A (en) * 2000-03-29 2013-12-31 Lycored Natural Prod Ind Ltd Use of Carotenoids in Preparing Pharmaceuticals to Prevent Adverse Effects from Hormones and Pharmaceuticals Containing Carotenoids
US20020031539A1 (en) * 2000-08-30 2002-03-14 The Brigham And Women's Hospital, Inc. Oxidized forms of retinoic acid as ligands for peroxisome proliferator activated receptor gamma
US20050037048A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices containing antioxidant and therapeutic agent
US20050064011A1 (en) * 2003-08-11 2005-03-24 Young-Ho Song Implantable or insertable medical devices containing phenolic compound for inhibition of restenosis
AU2005213895A1 (en) * 2004-02-19 2005-09-01 Chemaphor Inc. Topical formulations for the treatment of skin conditions
KR101327590B1 (ko) 2004-09-28 2013-11-12 체마폴, 인코포레이티드. 체중 증가 및 사료 전환을 촉진하는 조성물 및 방법
WO2007043046A2 (en) * 2005-10-11 2007-04-19 Lycored Ltd. Carotenoid oxidation products as chemopreventive and chemotherapeutic agents
RU2008143560A (ru) * 2006-04-05 2010-05-10 Кемафор Инк. (Ca) Пищевая добавка, содержащая каротиноид
US8003621B2 (en) 2007-09-14 2011-08-23 Nitto Denko Corporation Drug carriers
NZ585620A (en) * 2007-10-26 2013-03-28 Ca Nat Research Council Compositions and methods for enhancing immune response
WO2010124391A1 (en) 2009-04-30 2010-11-04 Chemaphor Inc. Methods and compositions for improving the health of animals
EP3288546B1 (en) * 2015-04-28 2021-12-15 Avivagen Inc. Oxidized carotenoids and components thereof for preventing necrotic enteritis
US20200206150A1 (en) * 2015-08-20 2020-07-02 I.B.R. Israeli Biotechnology Research Ltd. Carotenoid compositions having antiviral activities and uses thereof
US20190054135A1 (en) * 2016-02-25 2019-02-21 Avivagen Inc. Plant or microorganism-derived carotenoid-oxygen copolymer compositions, methods of identifying, quantifying and producing same and uses thereof
CN106614301A (zh) * 2016-11-14 2017-05-10 鄂尔多斯市绿食保山羊食品有限公司 山羊的有机养殖方法
KR102683182B1 (ko) * 2021-11-12 2024-07-11 주식회사 에이펙셀 메타 아르세나이트 염을 포함하는 암 치료용 약학 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2505869C3 (de) * 1975-02-12 1978-05-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von symmetrischen Carotinoiden
DE2635802C2 (de) * 1976-08-09 1984-03-01 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von symmetrischen Carotinoiden
US5225604A (en) * 1989-11-27 1993-07-06 Neurosearch A/S Hydroxycarbonyl derivatives and process for making the same
DK595489D0 (da) * 1989-11-27 1989-11-27 Neurosearch As Hydroxycarbonylderivater og fremgangsmaade til fremstilling af samme
US5310554A (en) * 1992-10-27 1994-05-10 Natural Carotene Corporation High purity beta-carotene
US5358915A (en) * 1993-02-12 1994-10-25 American Colloid Company Process for regenerating spent acid-activated bentonite clays and smectite catalysts

Also Published As

Publication number Publication date
KR960704828A (ko) 1996-10-09
FI961544A0 (fi) 1996-04-09
AU704640B2 (en) 1999-04-29
GB2297325B (en) 1999-01-13
JPH09504038A (ja) 1997-04-22
DE69521020T2 (de) 2001-11-15
DE69521020D1 (de) 2001-06-28
AU3160095A (en) 1996-03-07
CN1131939A (zh) 1996-09-25
PT722431E (pt) 2001-11-30
PL184296B1 (pl) 2002-09-30
CA2171625C (en) 2008-10-14
EP0722431B1 (en) 2001-05-23
JP3983800B2 (ja) 2007-09-26
ATE201394T1 (de) 2001-06-15
US5475006A (en) 1995-12-12
PL313907A1 (en) 1996-08-05
WO1996005160A1 (en) 1996-02-22
GB9604444D0 (en) 1996-05-01
MX9601175A (es) 1997-06-28
EP0722431A1 (en) 1996-07-24
FI961544A (fi) 1996-04-09
NZ290769A (en) 1998-08-26
KR100404724B1 (ko) 2004-04-03
ES2160172T3 (es) 2001-11-01
GB2297325A (en) 1996-07-31
CA2171625A1 (en) 1996-02-22
CZ103896A3 (en) 1996-11-13

Similar Documents

Publication Publication Date Title
GB2297325B (en) Oxidized carotenoids, retinoids and related conjugated polyenes, and derived fractions and compounds useful as cell-differentiation inducers, cytostatic agent
Astorg Food carotenoids and cancer prevention: an overview of current research
Blumberg Considerations of the scientific substantiation for antioxidant vitamins and beta-carotene in disease prevention
Gradelet et al. β-Apo-8′-carotenal, but not β-carotene, is a strong inducer of liver cytochromes P4501A1 and 1A2 in rat
Skaper et al. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid
Nara et al. Acyclic carotenoids and their oxidation mixtures inhibit the growth of HL-60 human promyelocytic leukemia cells
Pryor et al. Beta carotene: from biochemistry to clinical trials
Frede et al. Stability and cellular uptake of lutein-loaded emulsions
Bendich Symposium conclusions: biological actions of carotenoids
Pérez-Gálvez et al. Degradation of non-esterified and esterified xanthophylls by free radicals
Pawson et al. Retinoids at the threshold: their biological significance and therapeutic potential
Hix et al. Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives
van Helden et al. β-Carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells
MXPA03009685A (es) Proceso para la preparacion de un xantofilo.
Lecchi et al. In vitro modulation of caprine monocyte immune functions by ω-3 polyunsaturated fatty acids
Murayama et al. Photoisomerization of retinoic acids in ethanol under room light: a warning for cell biological study of geometrical isomers of retinoids
Kim et al. Animal models in carotenoids research and lung cancer prevention
Naves et al. β-carotene and cancer chemoprevention: From epidemiological associations to cellular mechanisms of action
JP2014240441A (ja) アスタキサンチン含有加齢臭抑制組成物
D’arrigo et al. Production of n-3 fatty acid enriched pork liver pâté
Deming et al. Carotenoids: Linking chemistry, absorption, and metabolism to potential roles in human health and disease
Wang et al. The bioconversion of β-carotene into retinoids
Glei et al. β-Carotene reduces bleomycin-induced genetic damage in human lymphocytes
Scheer et al. Chemoprevention of oral squamous cell carcinomas
IARC Working Group on the Evaluation of Cancer-preventive Agents et al. Carotenoids

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110810