HK1012405A1 - Hybrid protein between cs from plasmodium and hbsag - Google Patents
Hybrid protein between cs from plasmodium and hbsagInfo
- Publication number
- HK1012405A1 HK1012405A1 HK98113572A HK98113572A HK1012405A1 HK 1012405 A1 HK1012405 A1 HK 1012405A1 HK 98113572 A HK98113572 A HK 98113572A HK 98113572 A HK98113572 A HK 98113572A HK 1012405 A1 HK1012405 A1 HK 1012405A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hbsag
- plasmodium
- hybrid protein
- protein
- falciparum
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 241000224016 Plasmodium Species 0.000 title 1
- 241000700721 Hepatitis B virus Species 0.000 abstract 1
- 241000223960 Plasmodium falciparum Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10123—Virus like particles [VLP]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919124390A GB9124390D0 (en) | 1991-11-16 | 1991-11-16 | Vaccines |
US84269492A | 1992-02-27 | 1992-02-27 | |
PCT/EP1992/002591 WO1993010152A1 (en) | 1991-11-16 | 1992-11-11 | HYBRID PROTEIN BETWEEN CS FROM PLASMODIUM AND HBsAG |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1012405A1 true HK1012405A1 (en) | 1999-07-30 |
Family
ID=26299880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98113572A HK1012405A1 (en) | 1991-11-16 | 1998-12-16 | Hybrid protein between cs from plasmodium and hbsag |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0614465B1 (da) |
JP (2) | JP3954643B2 (da) |
KR (1) | KR100251505B1 (da) |
AT (1) | ATE177755T1 (da) |
AU (2) | AU2927892A (da) |
CA (1) | CA2123612C (da) |
DE (1) | DE69228698T2 (da) |
DK (1) | DK0614465T3 (da) |
ES (1) | ES2129461T3 (da) |
GR (1) | GR3029717T3 (da) |
HK (1) | HK1012405A1 (da) |
MX (1) | MX9206574A (da) |
NZ (1) | NZ245114A (da) |
PT (1) | PT101052B (da) |
SG (1) | SG48390A1 (da) |
WO (1) | WO1993010152A1 (da) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6620414B2 (en) | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
NZ253137A (en) | 1992-06-25 | 1996-08-27 | Smithkline Beecham Biolog | Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a. |
GB9616351D0 (en) * | 1996-08-02 | 1996-09-11 | Smithkline Beecham Biolog | Vaccine composition |
CA2347099C (en) | 1998-10-16 | 2014-08-05 | Smithkline Beecham Biologicals S.A. | Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof |
GB9915204D0 (en) * | 1999-06-29 | 1999-09-01 | Smithkline Beecham Biolog | Vaccine |
GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
US8232255B2 (en) | 2002-10-23 | 2012-07-31 | Glaxosmithkline Biologicals S.A. | Methods for vaccinating against malaria |
WO2004055187A1 (en) | 2002-12-17 | 2004-07-01 | Crucell Holland B.V. | Recombinant viral-based malaria vaccines |
WO2004106525A1 (fr) * | 2003-06-03 | 2004-12-09 | Shanghai Centre Of Research & Development Of New Drugs | Proteine de fusion pouvant etre exprimee tres efficacement et son procede de production |
EP1925626A1 (en) | 2003-07-21 | 2008-05-28 | Transgene S.A. | Novel multifunctional cytokines |
GB0420634D0 (en) | 2004-09-16 | 2004-10-20 | Glaxosmithkline Biolog Sa | Vaccines |
JP5108521B2 (ja) * | 2004-10-14 | 2012-12-26 | クルセル ホランド ベー ヴェー | マラリア初回免疫/追加免疫ワクチン |
US8119146B2 (en) | 2005-04-18 | 2012-02-21 | Angelica Medina-Selby | Expressing hepatitis B virus surface antigen for vaccine preparation |
GB0513421D0 (en) * | 2005-06-30 | 2005-08-03 | Glaxosmithkline Biolog Sa | Vaccines |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0614254D0 (en) * | 2006-07-18 | 2006-08-30 | Smithkline Beecham Biolog | Vaccine |
MX2009000650A (es) | 2006-07-18 | 2009-07-02 | Secretary Of The Army The Unit | Vacunas para malaria. |
WO2008028957A2 (en) | 2006-09-07 | 2008-03-13 | Glaxosmithkline Biologicals S.A. | Vaccine |
DK2068918T4 (da) | 2006-09-26 | 2024-09-02 | Access To Advanced Health Inst | Vaccinesammensætning omfattende syntetisk adjuvant |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
CA2664619C (en) | 2006-10-12 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | Immunogenic compositions comprising an oil-in-water emulsion adjuvant containing a reduced amount of squalene, tocol and an emulsifying agent |
EP2433648A3 (en) | 2006-10-12 | 2012-04-04 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising an oil in water emulsion adjuvant |
EA021391B1 (ru) | 2007-03-02 | 2015-06-30 | Глаксосмитклайн Байолоджикалс С.А. | Способ индукции иммунного ответа, вакцинная композиция, ее применение и набор |
US9717788B2 (en) | 2007-03-02 | 2017-08-01 | Glaxosmithkline Biologicals Sa | Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant |
TW200908994A (en) | 2007-04-20 | 2009-03-01 | Glaxosmithkline Biolog Sa | Vaccine |
NZ583150A (en) | 2007-08-13 | 2012-05-25 | Glaxosmithkline Biolog Sa | Use of an antigen derived from the circumsporozoite protein (CS) protein of Plasmodium falciparum in the manufacture of a medicament for vaccinating infants against malaria |
WO2009080803A1 (en) | 2007-12-24 | 2009-07-02 | Glaxosmithkline Biologicals S.A. | Vaccines for malaria |
GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
EP3124491B1 (en) | 2009-06-05 | 2019-10-30 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants and vaccine compositions as well as pharmaceutical compositions containing them |
US9555089B2 (en) | 2009-08-18 | 2017-01-31 | The Rockefeller University | Modification of recombinant adenovirus with immunogenic plasmodium circumsporozoite protein epitopes |
MX354752B (es) | 2010-09-27 | 2018-03-20 | Janssen Vaccines & Prevention Bv | Regimen de vacunacion de sensibilizacion y refuerzo heterologo contra malaria. |
GB201022007D0 (en) | 2010-12-24 | 2011-02-02 | Imp Innovations Ltd | DNA-sensor |
JP6054942B2 (ja) | 2011-04-08 | 2016-12-27 | イミューン デザイン コーポレイション | 免疫原性組成物、ならびに体液性および細胞性免疫応答を誘発するための該組成物の使用方法 |
GB201116248D0 (en) | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
PL2811981T3 (pl) | 2012-02-07 | 2019-09-30 | Infectious Disease Research Institute | Ulepszone formulacje adiuwantowe zawierające agonistę TLR4 oraz sposoby ich zastosowania |
AU2013221187B9 (en) | 2012-02-16 | 2018-01-04 | Vlp Therapeutics, Inc. | Virus like particle composition |
CN107540730B (zh) | 2012-05-16 | 2021-07-16 | 免疫设计公司 | 用于hsv-2的疫苗 |
CN109134640A (zh) | 2012-10-23 | 2019-01-04 | 爱默蕾大学 | Gm-csf和il-4轭合物、组合物以及与其相关的方法 |
US20150344529A1 (en) | 2012-12-25 | 2015-12-03 | The Chemo-Sero-Therapeutic Research Institute | Vaccine for hpv infection and/or hepatitis b comprising hpv/hbs chimeric protein as active ingredient |
DK2941269T3 (da) | 2013-01-07 | 2021-01-11 | Mucosal Vaccine Tech Llc | Terapeutiske vacciner til behandling af herpes simplex-virus type 2-infektioner |
WO2014111733A1 (en) * | 2013-01-21 | 2014-07-24 | Isis Innovation Limited | Composition and uses thereof |
BE1022174B1 (fr) | 2013-03-15 | 2016-02-24 | Glaxosmithkline Biologicals S.A. | Vaccin |
BR112015025709A2 (pt) | 2013-04-18 | 2017-07-18 | Immune Design Corp | monoterapia com gla para uso em tratamento de câncer |
SG10201709917VA (en) * | 2013-06-03 | 2017-12-28 | Vlp Therapeutics Llc | Malaria vaccine |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
TWI676636B (zh) | 2013-07-12 | 2019-11-11 | Vlp醫療股份有限公司 | 包含pd-1抗原或pd-1配體抗原的類病毒粒子 |
EP2873728A1 (en) | 2013-11-18 | 2015-05-20 | Institut Pasteur | A subunit vaccine platform based on multimeric ribonucleoproteins comprising nucleoproteins of a non-segmented negative-strand RNA virus as carriers of heterologous polypeptides |
KR102411781B1 (ko) | 2013-12-31 | 2022-06-22 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | 단일 바이알 백신 제형 |
EP3177720B1 (en) | 2014-08-08 | 2021-09-22 | VLP Therapeutics, Inc. | Virus like particle comprising modified envelope protein e3 |
US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
PT3188755T (pt) | 2014-09-01 | 2020-09-29 | Int Centre For Genetic Engineering And Biotechnology | Vacina |
SG11201701669PA (en) | 2014-09-11 | 2017-04-27 | Vlp Therapeutics Llc | Flavivirus virus like particle |
WO2016184784A1 (en) | 2015-05-15 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Peptides including binding domain of plasmodium falciparum proteins (cbp1 and cbp2) to chemokine cx3cl1 |
WO2017176076A1 (en) | 2016-04-06 | 2017-10-12 | Ewha University - Industry Collaboration Foundation | A peptide with ability to penetrate cell membrane |
CA3023672A1 (en) | 2016-05-16 | 2017-11-23 | Infectious Disease Research Institute | Pegylated liposomes and methods of use |
ES2929054T3 (es) | 2016-05-16 | 2022-11-24 | Access To Advanced Health Inst | Formulación que contiene un agonista de TLR y métodos de uso |
WO2017210364A1 (en) | 2016-06-01 | 2017-12-07 | Infectious Disease Research Institute | Nanoalum particles containing a sizing agent |
BE1025160B1 (fr) | 2016-12-07 | 2018-11-26 | Glaxosmithkline Biologicals Sa | Nouveau procédé |
GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
GB201707700D0 (en) | 2017-05-12 | 2017-06-28 | Glaxosmithkline Biologicals Sa | Dried composition |
US12016919B2 (en) | 2017-05-30 | 2024-06-25 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
KR102673794B1 (ko) | 2017-06-15 | 2024-06-11 | 액세스 투 어드밴스드 헬스 인스티튜트 | 나노구조 지질 담체 및 안정적인 에멀션 그리고 이들의 용도 |
WO2019051149A1 (en) | 2017-09-08 | 2019-03-14 | Infectious Disease Research Institute | LIPOSOMAL FORMULATIONS COMPRISING SAPONIN AND METHODS OF USE |
CA3083078A1 (en) | 2017-12-01 | 2019-06-06 | Glaxosmithkline Biologicals Sa | Saponin purification |
US20220177558A1 (en) | 2019-03-25 | 2022-06-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Treatment of taupathy disorders by targeting new tau species |
AU2020283768A1 (en) | 2019-05-25 | 2021-12-23 | Access To Advanced Health Institute | Composition and method for spray drying an adjuvant vaccine emulsion |
JP2022535091A (ja) | 2019-06-05 | 2022-08-04 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サポニン精製 |
CA3174411A1 (en) | 2020-09-04 | 2022-03-10 | Ryan M. Kramer | Co-lyophilized rna and nanostructured lipid carrier |
IL309422A (en) | 2021-06-17 | 2024-02-01 | Atreca Inc | Antibodies against CSP |
EP4169513A1 (en) | 2021-10-19 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Adjuvant composition comprising sting agonists |
WO2024052882A1 (en) | 2022-09-09 | 2024-03-14 | Access To Advanced Health Institute | Immunogenic vaccine composition incorporating a saponin |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE70308T1 (de) * | 1984-09-12 | 1991-12-15 | Chiron Corp | Hybridpartikel-immunogene. |
US4722840A (en) * | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
AP56A (en) * | 1987-01-30 | 1989-09-26 | Smithkline Biologicals S A | Hepatitis B virus surface antigens and hybrid antigehs containing them. |
US4886782A (en) * | 1987-02-26 | 1989-12-12 | The United States Of America As Represented By The Department Of Health And Human Services | Malarial immunogen |
CA1341074C (en) * | 1987-06-22 | 2000-08-08 | Hans A. Thoma | Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine |
GB8812214D0 (en) * | 1988-05-24 | 1988-06-29 | Hoffmann La Roche | Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope |
US5028425A (en) * | 1988-07-07 | 1991-07-02 | The United States Of America As Represented By The Department Of Health And Human Services | Synthetic vaccine against P. falciparum malaria |
-
1992
- 1992-11-11 AU AU29278/92A patent/AU2927892A/en not_active Abandoned
- 1992-11-11 EP EP92923486A patent/EP0614465B1/en not_active Expired - Lifetime
- 1992-11-11 JP JP50895793A patent/JP3954643B2/ja not_active Expired - Lifetime
- 1992-11-11 AT AT92923486T patent/ATE177755T1/de active
- 1992-11-11 WO PCT/EP1992/002591 patent/WO1993010152A1/en active IP Right Grant
- 1992-11-11 DE DE69228698T patent/DE69228698T2/de not_active Expired - Lifetime
- 1992-11-11 ES ES92923486T patent/ES2129461T3/es not_active Expired - Lifetime
- 1992-11-11 DK DK92923486T patent/DK0614465T3/da active
- 1992-11-11 KR KR1019940701652A patent/KR100251505B1/ko not_active IP Right Cessation
- 1992-11-11 SG SG1996009300A patent/SG48390A1/en unknown
- 1992-11-11 CA CA002123612A patent/CA2123612C/en not_active Expired - Lifetime
- 1992-11-13 PT PT101052A patent/PT101052B/pt not_active IP Right Cessation
- 1992-11-13 NZ NZ245114A patent/NZ245114A/en not_active IP Right Cessation
- 1992-11-13 MX MX9206574A patent/MX9206574A/es unknown
-
1997
- 1997-02-14 AU AU14717/97A patent/AU712409B2/en not_active Expired
-
1998
- 1998-12-16 HK HK98113572A patent/HK1012405A1/xx not_active IP Right Cessation
-
1999
- 1999-03-18 GR GR990400668T patent/GR3029717T3/el unknown
-
2007
- 2007-03-15 JP JP2007066032A patent/JP4241846B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK0614465T3 (da) | 1999-09-27 |
JP4241846B2 (ja) | 2009-03-18 |
KR100251505B1 (ko) | 2000-05-01 |
JPH07501213A (ja) | 1995-02-09 |
SG48390A1 (en) | 1998-04-17 |
ATE177755T1 (de) | 1999-04-15 |
ES2129461T3 (es) | 1999-06-16 |
CA2123612A1 (en) | 1993-05-27 |
MX9206574A (es) | 1993-05-01 |
EP0614465A1 (en) | 1994-09-14 |
EP0614465B1 (en) | 1999-03-17 |
AU712409B2 (en) | 1999-11-04 |
WO1993010152A1 (en) | 1993-05-27 |
NZ245114A (en) | 1995-07-26 |
DE69228698D1 (de) | 1999-04-22 |
AU1471797A (en) | 1997-06-12 |
PT101052A (pt) | 1994-01-31 |
DE69228698T2 (de) | 1999-09-16 |
CA2123612C (en) | 2002-06-25 |
JP3954643B2 (ja) | 2007-08-08 |
PT101052B (pt) | 1999-10-29 |
AU2927892A (en) | 1993-06-15 |
GR3029717T3 (en) | 1999-06-30 |
JP2007209343A (ja) | 2007-08-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GR3029717T3 (en) | HYBRID PROTEIN BETWEEN CS FROM PLASMODIUM AND HBsAG. | |
HK1021142A1 (en) | Combined vaccines comprising hepatitis b surface antigen and other antigens | |
AU9052091A (en) | Vaccines based on hepatitis b surface antigen | |
PL324906A1 (en) | Vaccines against viral hepatitis of c type | |
AP8800078A0 (en) | Hepatitis b virus surface antigens and hybrid antigens containing them | |
EP0687182A4 (en) | PEPTIDES FOR INDUCING A RESPONSE OF THE CYTOTOXIC T-LYMPHOCYTES AGAINST THE HEPATITIS B VIRUS | |
PT85137A (en) | T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen | |
NZ219516A (en) | Fusion proteins of hbcag (hepatitis b virus core antigen) | |
LU91458I2 (fr) | "Virus atténué des oreillons,souche RIT4385 (JL-1); virus atténué de la rougeole ; virus atténué de la rubéole ; et virus atténué de la varicelle." | |
AU2370592A (en) | Epitopes of the env protein of the hepatitis c virus | |
TR199501557A2 (tr) | PreS2 peptid iceren hepatiti b viral yüzey antijenini aritma prosesi. | |
IL90134A0 (en) | Gene for encoding a human malaria vaccine antigen,malarial vaccines and pharmaceutical compositions | |
KR890701743A (ko) | B형 간염 표면 항원 백신 | |
EP0542753A4 (en) | Epitopes of the pre-s region of hepatitis b virus surface antigen | |
AU7542287A (en) | Vaccines containing epitopes of both the csp and a blood stage antigen of a plasmodium parasite | |
OA08974A (en) | New immunologically active synthetic peptides useful for preparing an antimalarial vaccine | |
ZA932210B (en) | A process for preparation of a recombinant hepatitis B surface antigen, and antigen and vaccine based thereon | |
AU3269793A (en) | Method for obtaining recombinant surface antigen of hepatitis B, antigen and vaccine based on it | |
EP0503252A3 (en) | Recombinant proteins having the immunoreactivity of hepatitis b virus e antigens (hbeag), method for their production and their application in immunoassays and as vaccines | |
NO930883L (no) | Peptider for bruk ved vaksinasjon og induksjon av noeytraliserende antistoffer mot hiv | |
ZA874498B (en) | T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen | |
GB9102294D0 (en) | Antigen of plasmodium falciparum | |
CS578887A1 (en) | Inactivated antigen of cattle's mucosal disease's virus | |
CS627787A1 (en) | Mouse lymphocytar hybridome producing antibodies against antigen of b-hepatitis virus (hbeag) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20121110 |