HK1012377A1 - Pharmaceutical composition containing bicyclic type compounds - Google Patents

Pharmaceutical composition containing bicyclic type compounds

Info

Publication number
HK1012377A1
HK1012377A1 HK98113578A HK98113578A HK1012377A1 HK 1012377 A1 HK1012377 A1 HK 1012377A1 HK 98113578 A HK98113578 A HK 98113578A HK 98113578 A HK98113578 A HK 98113578A HK 1012377 A1 HK1012377 A1 HK 1012377A1
Authority
HK
Hong Kong
Prior art keywords
alkyl
hydrogen
substituted
alkylcarbonyl
cyano
Prior art date
Application number
HK98113578A
Other languages
English (en)
Inventor
Wai Ngor Chan
John Morris Evans
Geoffrey Stemp
Neil Upton
Robert Nicholas Willette
Original Assignee
Smithkline Beecham Plc
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929225858A external-priority patent/GB9225858D0/en
Priority claimed from GB929225861A external-priority patent/GB9225861D0/en
Priority claimed from GB929225857A external-priority patent/GB9225857D0/en
Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp filed Critical Smithkline Beecham Plc
Publication of HK1012377A1 publication Critical patent/HK1012377A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK98113578A 1992-12-11 1998-12-16 Pharmaceutical composition containing bicyclic type compounds HK1012377A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929225858A GB9225858D0 (en) 1992-12-11 1992-12-11 Novel treatment
GB929225861A GB9225861D0 (en) 1992-12-11 1992-12-11 Novel treatment
GB929225857A GB9225857D0 (en) 1992-12-11 1992-12-11 Novel treatment
PCT/GB1993/002513 WO1994013657A1 (en) 1992-12-11 1993-12-08 Pharmaceutical composition containing bicyclic type compounds

Publications (1)

Publication Number Publication Date
HK1012377A1 true HK1012377A1 (en) 1999-07-30

Family

ID=27266506

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113578A HK1012377A1 (en) 1992-12-11 1998-12-16 Pharmaceutical composition containing bicyclic type compounds

Country Status (17)

Country Link
US (1) US5948811A (ko)
EP (1) EP0673374B1 (ko)
JP (2) JP3568533B2 (ko)
KR (1) KR100305149B1 (ko)
CN (1) CN1059441C (ko)
AT (1) ATE190055T1 (ko)
AU (1) AU679955B2 (ko)
DE (1) DE69327965T2 (ko)
DK (1) DK0673374T3 (ko)
ES (1) ES2143541T3 (ko)
GR (1) GR3033280T3 (ko)
HK (1) HK1012377A1 (ko)
MX (1) MX9307791A (ko)
NZ (1) NZ258611A (ko)
PT (1) PT673374E (ko)
SG (1) SG49907A1 (ko)
WO (1) WO1994013657A1 (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69524871T2 (de) * 1994-06-10 2002-08-22 Smithkline Beecham Plc Benzopyrans und deren verwendung als therapeutische mittel
DE69518322T2 (de) * 1994-06-10 2001-02-15 Smithkline Beecham Plc C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittel
GB9411635D0 (en) 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
US5574049A (en) * 1994-07-22 1996-11-12 Sandoz Ltd. 2,2-dialkyl- and 2,2-dialkyl-3,4-dihydro-3-hydroxy-2H-1-benzopyrans
GB9726543D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel compositions
GB9813949D0 (en) * 1998-06-29 1998-08-26 Smithkline Beecham Plc Novel compounds
US6589962B1 (en) 1999-07-20 2003-07-08 Merck & Co., Inc. Alpha-hydroxy-gamma-[[(carbocyclic-or heterocyclic-substituted)amino]carbonyl]alkanamide derivatives and uses thereof
GB0028697D0 (en) * 2000-11-23 2001-01-10 S P A Novel process
US7576094B2 (en) * 2004-12-13 2009-08-18 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors
AU2010325755A1 (en) * 2009-12-03 2012-06-21 Proximagen Ltd Treatment of infectious diseases
RU2012124837A (ru) 2009-12-03 2014-01-10 Проксимэджен ЛТД Лечение аллодинии и гипералгезии
US20140011773A1 (en) 2012-07-03 2014-01-09 Proximagen Limited Pro-drug Compounds
GB201322932D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Pro-drug compounds
CN114010788A (zh) 2014-08-22 2022-02-08 奥克兰联合服务有限公司 通道调节剂
WO2019018691A1 (en) 2017-07-19 2019-01-24 Auckland Uniservices Limited MODULATION OF CYTOKINE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126311B1 (en) * 1983-05-18 1989-09-13 Beecham Group Plc Benzopyran derivatives.
EP0139992B1 (en) * 1983-09-01 1988-12-28 Beecham Group Plc Chromanol derivatives
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
EP0271271B1 (en) * 1986-12-06 1992-01-15 Beecham Group Plc Pharmaceutical preparations
GB9112721D0 (en) * 1991-06-13 1991-07-31 Smithkline Beecham Plc Novel treatment

Also Published As

Publication number Publication date
KR950704293A (ko) 1995-11-17
DE69327965D1 (de) 2000-04-06
GR3033280T3 (en) 2000-09-29
AU679955B2 (en) 1997-07-17
WO1994013657A1 (en) 1994-06-23
JPH11500405A (ja) 1999-01-12
CN1094722A (zh) 1994-11-09
US5948811A (en) 1999-09-07
NZ258611A (en) 1997-07-27
EP0673374B1 (en) 2000-03-01
PT673374E (pt) 2000-07-31
DK0673374T3 (da) 2000-07-31
CN1059441C (zh) 2000-12-13
KR100305149B1 (ko) 2001-11-22
DE69327965T2 (de) 2000-10-19
SG49907A1 (en) 1998-06-15
JP2003137779A (ja) 2003-05-14
MX9307791A (es) 1995-01-31
ES2143541T3 (es) 2000-05-16
EP0673374A1 (en) 1995-09-27
AU5655894A (en) 1994-07-04
JP3568533B2 (ja) 2004-09-22
ATE190055T1 (de) 2000-03-15

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20131207