HK1011351A1 - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- HK1011351A1 HK1011351A1 HK98112039A HK98112039A HK1011351A1 HK 1011351 A1 HK1011351 A1 HK 1011351A1 HK 98112039 A HK98112039 A HK 98112039A HK 98112039 A HK98112039 A HK 98112039A HK 1011351 A1 HK1011351 A1 HK 1011351A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- quinoline derivatives
- quinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP28109490 | 1990-10-19 | ||
JP28109390 | 1990-10-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1011351A1 true HK1011351A1 (en) | 1999-07-09 |
Family
ID=26554052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98112039A HK1011351A1 (en) | 1990-10-19 | 1998-11-16 | Quinoline derivatives |
Country Status (8)
Country | Link |
---|---|
US (2) | US5190951A (xx) |
EP (2) | EP0987262A1 (xx) |
KR (1) | KR100206200B1 (xx) |
CA (1) | CA2053640C (xx) |
DE (1) | DE69132519T2 (xx) |
ES (1) | ES2156853T3 (xx) |
HK (1) | HK1011351A1 (xx) |
SG (1) | SG44523A1 (xx) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5190951A (en) * | 1990-10-19 | 1993-03-02 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
ATE209036T1 (de) * | 1995-06-15 | 2001-12-15 | Upjohn Co | Verwendung von imidazo(a,5-a)quinolonen als neuroprotektive arzneimittel |
EP1086102A1 (en) * | 1998-06-10 | 2001-03-28 | Arena Pharmaceuticals, Inc. | Acetylcholine enhancers |
US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
EP1891954A3 (en) | 1998-09-30 | 2009-01-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder |
US20030220646A1 (en) * | 2002-05-23 | 2003-11-27 | Thelen Sarah L. | Method and apparatus for reducing femoral fractures |
UA72611C2 (uk) | 2000-05-17 | 2005-03-15 | Орто-Макнейл Фармацевтикал, Інк. | Похідні заміщеного піролопіридинону, корисні як інгібітори фосфодіестерази |
US6800625B2 (en) | 2002-06-19 | 2004-10-05 | Janssen Pharmaceutica N.V. | Substituted 2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one derivatives useful as phosphodiesterase inhibitors |
GB0522715D0 (en) | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
WO2007073283A1 (en) * | 2005-12-20 | 2007-06-28 | Astrazeneca Ab | Substituted cinnoline derivatives as gabaa-receptor modulators and method for their synthesis |
US7465795B2 (en) * | 2005-12-20 | 2008-12-16 | Astrazeneca Ab | Compounds and uses thereof |
AR067028A1 (es) * | 2007-06-19 | 2009-09-30 | Astrazeneca Ab | Compuestos y usos de los mismos 849 |
TW200904817A (en) * | 2007-06-19 | 2009-02-01 | Astrazeneca Ab | Compounds and uses thereof |
BR112012019923A2 (pt) | 2010-02-09 | 2016-08-09 | Univ Johns Hopkins | métodos e composições para melhorar a função cognitiva |
EP2640391B1 (en) | 2010-11-15 | 2015-11-11 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
US9221760B2 (en) | 2011-05-09 | 2015-12-29 | Van Andel Research Institute | Autophagy inhibitors |
CN102875602B (zh) * | 2012-10-25 | 2015-05-20 | 江苏神龙药业有限公司 | 一种米诺膦酸水合物的制备方法 |
CA2891122C (en) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
EP2968220B1 (en) | 2013-03-15 | 2021-05-05 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
WO2015095783A1 (en) | 2013-12-20 | 2015-06-25 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
CN107810002B (zh) | 2015-05-22 | 2021-01-05 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
JP6987384B2 (ja) | 2015-06-19 | 2021-12-22 | エージンバイオ, インコーポレイテッド | ベンゾジアゼピン誘導体、組成物、および認知障害を処置するための方法 |
US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
BR112020026062B1 (pt) | 2018-06-19 | 2023-04-04 | Agenebio, Inc | Compostos derivados de benzodiazepina ou um sal farmaceuticamente aceitavel, isômero ou combinação dos mesmos, composição farmacêutica compreendendo os mesmos e usos dos mesmos para o tratamento de comprometimento cognitivo, câncer cerebral e psicose da doença de parkinson |
CN112608326B (zh) * | 2021-01-22 | 2021-10-01 | 河南大学 | 呋喃并[2,3-b]喹啉-3,4(2H,9H)-二酮衍生物、其制备方法及应用 |
CN114989180B (zh) * | 2022-05-26 | 2024-06-04 | 广东海洋大学 | 杨叶肖槿内生真菌来源的化合物及其制备方法与应用 |
WO2024039886A1 (en) | 2022-08-19 | 2024-02-22 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ216720A (en) * | 1985-07-08 | 1990-09-26 | Bristol Myers Co | Diazinylpiperidine derivatives and pharmaceutical compositions |
DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
JP2507076B2 (ja) * | 1989-08-11 | 1996-06-12 | 株式会社クボタ | カ―ド式自動販売機 |
US5190951A (en) * | 1990-10-19 | 1993-03-02 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
US5240934A (en) * | 1990-10-19 | 1993-08-31 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
-
1991
- 1991-10-09 US US07/773,432 patent/US5190951A/en not_active Expired - Lifetime
- 1991-10-15 SG SG1996001518A patent/SG44523A1/en unknown
- 1991-10-15 EP EP99124146A patent/EP0987262A1/en not_active Withdrawn
- 1991-10-15 DE DE69132519T patent/DE69132519T2/de not_active Expired - Fee Related
- 1991-10-15 EP EP91117581A patent/EP0481429B1/en not_active Expired - Lifetime
- 1991-10-15 ES ES91117581T patent/ES2156853T3/es not_active Expired - Lifetime
- 1991-10-16 KR KR1019910018237A patent/KR100206200B1/ko not_active IP Right Cessation
- 1991-10-17 CA CA002053640A patent/CA2053640C/en not_active Expired - Fee Related
-
1993
- 1993-04-28 US US08/053,202 patent/US5300517A/en not_active Expired - Fee Related
-
1998
- 1998-11-16 HK HK98112039A patent/HK1011351A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69132519D1 (de) | 2001-03-01 |
DE69132519T2 (de) | 2001-06-13 |
EP0987262A1 (en) | 2000-03-22 |
CA2053640A1 (en) | 1992-04-20 |
KR100206200B1 (ko) | 1999-07-01 |
CA2053640C (en) | 2001-12-25 |
EP0481429A3 (en) | 1992-08-19 |
KR920008024A (ko) | 1992-05-27 |
US5190951A (en) | 1993-03-02 |
SG44523A1 (en) | 1997-12-19 |
US5300517A (en) | 1994-04-05 |
ES2156853T3 (es) | 2001-08-01 |
EP0481429B1 (en) | 2001-01-24 |
EP0481429A2 (en) | 1992-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
AS | Change of ownership |
Owner name: BIOMEDIX CO., LTD. Free format text: FORMER OWNER(S): SS PHARMACEUTICAL CO., LTD |
|
CHPA | Change of a particular in the register (except of change of ownership) | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20071015 |