GT200700062A - Derivados de amina utiles como agentes anticancerigenos - Google Patents

Derivados de amina utiles como agentes anticancerigenos

Info

Publication number
GT200700062A
GT200700062A GT200700062A GT200700062A GT200700062A GT 200700062 A GT200700062 A GT 200700062A GT 200700062 A GT200700062 A GT 200700062A GT 200700062 A GT200700062 A GT 200700062A GT 200700062 A GT200700062 A GT 200700062A
Authority
GT
Guatemala
Prior art keywords
amina
anticancerigen
agents
useful derivatives
transformation
Prior art date
Application number
GT200700062A
Other languages
English (en)
Inventor
Matthew Stephen Corbett
Goss Stryker Kauffman
Kevin Daniel Freeman-Cook
Blaise Scott Lippa
Michael Joseph Luzzio
Joel Morris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200700062A publication Critical patent/GT200700062A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE FORMULA GENERAL I EN LA QUE A,L,R1,R2,R5,R6,U, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS DERIVADOS DE AMINA IMPIDEN LA TRANSFORMACION DE UNA PARTE DEL ADN DE UNA CELULA EN UN ONCOGEN QUE PUEDE LLEGAR A SER CANCEROSA A NIVEL DE LAS QUINASAS ABERRANTES CAPACES DE CAUSAR TRANSFORMACION CELULAR POR LO QUE SON DE UTILIDAD EN TRASTORNOS HIPERPROLIFERATIVOS TALES COMO EL CANCER. T2007
GT200700062A 2006-07-26 2007-07-24 Derivados de amina utiles como agentes anticancerigenos GT200700062A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82044106P 2006-07-26 2006-07-26

Publications (1)

Publication Number Publication Date
GT200700062A true GT200700062A (es) 2008-08-08

Family

ID=38963178

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200700062A GT200700062A (es) 2006-07-26 2007-07-24 Derivados de amina utiles como agentes anticancerigenos

Country Status (7)

Country Link
AR (1) AR062050A1 (es)
CL (1) CL2007002188A1 (es)
GT (1) GT200700062A (es)
PE (1) PE20080689A1 (es)
TW (1) TW200817408A (es)
UY (1) UY30499A1 (es)
WO (1) WO2008012635A2 (es)

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US8846683B2 (en) 2007-07-05 2014-09-30 Array Biopharma, Inc. Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
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US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
TWI450720B (zh) 2007-07-05 2014-09-01 Array Biopharma Inc 作為ａｋｔ蛋白質激酶抑制劑之嘧啶環戊烷
WO2009089352A1 (en) 2008-01-08 2009-07-16 Array Biopharma Inc. Pyrrolopyridines as kinase inhibitors
ES2401685T3 (es) 2008-01-09 2013-04-23 Array Biopharma, Inc. Pirimidil ciclopentano hidroxilado como inhibidor de la proteína quinasa AKT
AU2009204025B2 (en) 2008-01-09 2014-02-20 Array Biopharma Inc. Hydroxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
CN101965347B (zh) 2008-01-09 2013-01-02 阵列生物制药公司 作为激酶抑制剂的吡唑并吡啶
AU2013218743B2 (en) * 2008-05-13 2016-04-28 Array Biopharma Inc. Pyrrolopyridines as kinase inhibitors
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DE102009005193A1 (de) * 2009-01-20 2010-07-22 Merck Patent Gmbh Neue heterocyclische Verbindungen als MetAP-2 Inhibitoren
US8481557B2 (en) 2009-04-11 2013-07-09 Array Biopharma Inc. Method of treatment using checkpoint kinase 1 inhibitors
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US8343977B2 (en) 2009-12-30 2013-01-01 Arqule, Inc. Substituted triazolo-pyrimidine compounds
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US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
CN103874689B (zh) 2011-04-01 2016-04-27 基因泰克公司 Akt抑制剂化合物和威罗菲尼的组合及使用方法
CN103841976A (zh) 2011-04-01 2014-06-04 基因泰克公司 Akt和mek抑制剂化合物的组合及其使用方法
LT2755958T (lt) * 2011-09-12 2017-11-10 Merck Patent Gmbh Aminopirimidino dariniai, skirti naudoti kaip kinazės aktyvumo moduliatoriai
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WO2016134294A1 (en) 2015-02-20 2016-08-25 Incyte Corporation Bicyclic heterocycles as fgfr4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
WO2017004134A1 (en) * 2015-06-29 2017-01-05 Nimbus Iris, Inc. Irak inhibitors and uses thereof
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US11466004B2 (en) 2018-05-04 2022-10-11 Incyte Corporation Solid forms of an FGFR inhibitor and processes for preparing the same
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Also Published As

Publication number Publication date
CL2007002188A1 (es) 2008-02-01
WO2008012635A2 (en) 2008-01-31
PE20080689A1 (es) 2008-06-14
AR062050A1 (es) 2008-08-10
UY30499A1 (es) 2008-02-29
WO2008012635A3 (en) 2008-05-08
TW200817408A (en) 2008-04-16

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