GR861760B - 1-substituted oxindole-3-carboxamides as anti-inflammatory and analgesic agents - Google Patents
1-substituted oxindole-3-carboxamides as anti-inflammatory and analgesic agentsInfo
- Publication number
- GR861760B GR861760B GR861760A GR860101760A GR861760B GR 861760 B GR861760 B GR 861760B GR 861760 A GR861760 A GR 861760A GR 860101760 A GR860101760 A GR 860101760A GR 861760 B GR861760 B GR 861760B
- Authority
- GR
- Greece
- Prior art keywords
- analgesic agents
- carboxamides
- inflammatory
- substituted oxindole
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75320085A | 1985-07-09 | 1985-07-09 | |
| US82129686A | 1986-01-22 | 1986-01-22 | |
| US06/825,017 US4678802A (en) | 1985-07-09 | 1986-01-31 | 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR861760B true GR861760B (en) | 1986-11-10 |
Family
ID=27419443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR861760A GR861760B (en) | 1985-07-09 | 1986-07-07 | 1-substituted oxindole-3-carboxamides as anti-inflammatory and analgesic agents |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0208510B1 (el) |
| JP (1) | JPH0610193B2 (el) |
| CN (1) | CN86105309A (el) |
| AT (1) | ATE67185T1 (el) |
| AU (1) | AU566065B2 (el) |
| CA (1) | CA1286663C (el) |
| DE (1) | DE3681358D1 (el) |
| DK (1) | DK324286A (el) |
| ES (2) | ES2001855A6 (el) |
| FI (1) | FI862882A (el) |
| GR (1) | GR861760B (el) |
| HU (2) | HUT41386A (el) |
| IE (1) | IE58566B1 (el) |
| IL (1) | IL79356A (el) |
| NO (1) | NO862750L (el) |
| NZ (1) | NZ216788A (el) |
| PH (1) | PH22641A (el) |
| PT (1) | PT82931B (el) |
| YU (2) | YU45346B (el) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE68593B1 (en) | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
| FR2655344B1 (fr) * | 1989-12-06 | 1992-04-03 | Sanofi Sa | Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant. |
| WO1991009598A1 (en) * | 1990-01-05 | 1991-07-11 | Pfizer Inc. | Azaoxindole derivatives |
| FR2677356B1 (fr) * | 1991-06-05 | 1995-03-17 | Sanofi Sa | Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant. |
| JPH08288983A (ja) * | 1995-04-17 | 1996-11-01 | Tokyo Tsuuki:Kk | リンガ回路 |
| US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
| US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6319912B1 (en) | 1999-05-04 | 2001-11-20 | American Home Products Corporation | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides |
| US6355648B1 (en) * | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
| US6380178B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Cyclic regimens using cyclocarbamate and cyclic amide derivatives |
| US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
| US6498154B1 (en) | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
| US6399593B1 (en) | 1999-05-04 | 2002-06-04 | Wyeth | Cyclic regimens using cyclic urea and cyclic amide derivatives |
| US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| US6444668B1 (en) | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
| US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
| US6358947B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
| US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
| US6407101B1 (en) | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
| US6329416B1 (en) | 1999-05-04 | 2001-12-11 | American Home Products Corporation | Combination regimens using 3,3-substituted indoline derivatives |
| US6423699B1 (en) | 1999-05-04 | 2002-07-23 | American Home Products Corporation | Combination therapies using benzimidazolones |
| US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
| US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
| US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
| UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| CA2416397A1 (en) | 2000-07-19 | 2003-01-16 | Ube Industries, Ltd. | Process for producing 5-fluorooxyindole and for producing intermediate therefor |
| JP2004529110A (ja) | 2001-03-06 | 2004-09-24 | アストラゼネカ アクチボラグ | 脈管損傷活性を有するインドール誘導体 |
| JP4770826B2 (ja) * | 2007-11-22 | 2011-09-14 | 大日本印刷株式会社 | ２−オキシインドール誘導体の製造法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US3882236A (en) | 1973-12-26 | 1975-05-06 | Lilly Co Eli | Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
-
1986
- 1986-07-02 EP EP86305144A patent/EP0208510B1/en not_active Expired - Lifetime
- 1986-07-02 DE DE8686305144T patent/DE3681358D1/de not_active Expired - Fee Related
- 1986-07-02 AT AT86305144T patent/ATE67185T1/de not_active IP Right Cessation
- 1986-07-07 PT PT82931A patent/PT82931B/pt not_active IP Right Cessation
- 1986-07-07 GR GR861760A patent/GR861760B/el unknown
- 1986-07-07 CA CA000513184A patent/CA1286663C/en not_active Expired - Fee Related
- 1986-07-08 FI FI862882A patent/FI862882A/fi not_active Application Discontinuation
- 1986-07-08 PH PH33993A patent/PH22641A/en unknown
- 1986-07-08 HU HU862844A patent/HUT41386A/hu not_active IP Right Cessation
- 1986-07-08 HU HU862844D patent/HU198015A/hu not_active IP Right Cessation
- 1986-07-08 YU YU1203/86A patent/YU45346B/xx unknown
- 1986-07-08 DK DK324286A patent/DK324286A/da not_active Application Discontinuation
- 1986-07-08 AU AU59847/86A patent/AU566065B2/en not_active Ceased
- 1986-07-08 ES ES8600191A patent/ES2001855A6/es not_active Expired
- 1986-07-08 JP JP61160675A patent/JPH0610193B2/ja not_active Expired - Lifetime
- 1986-07-08 IL IL79356A patent/IL79356A/xx not_active IP Right Cessation
- 1986-07-08 NZ NZ216788A patent/NZ216788A/xx unknown
- 1986-07-08 IE IE183386A patent/IE58566B1/en not_active IP Right Cessation
- 1986-07-08 NO NO862750A patent/NO862750L/no unknown
- 1986-07-09 CN CN198686105309A patent/CN86105309A/zh active Pending
-
1987
- 1987-06-18 YU YU01144/87A patent/YU114487A/xx unknown
- 1987-12-15 ES ES8703589A patent/ES2009227A6/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| YU120386A (en) | 1988-02-29 |
| DK324286D0 (da) | 1986-07-08 |
| IE58566B1 (en) | 1993-10-06 |
| NO862750L (no) | 1987-01-12 |
| IL79356A (en) | 1990-03-19 |
| IL79356A0 (en) | 1986-10-31 |
| YU114487A (en) | 1988-02-29 |
| PT82931B (pt) | 1989-01-30 |
| DK324286A (da) | 1987-01-10 |
| AU566065B2 (en) | 1987-10-08 |
| NZ216788A (en) | 1988-10-28 |
| ES2009227A6 (es) | 1989-09-16 |
| PH22641A (en) | 1988-10-28 |
| CA1286663C (en) | 1991-07-23 |
| ATE67185T1 (de) | 1991-09-15 |
| PT82931A (en) | 1986-08-01 |
| ES2001855A6 (es) | 1988-07-01 |
| FI862882A0 (fi) | 1986-07-08 |
| YU45346B (en) | 1992-05-28 |
| DE3681358D1 (de) | 1991-10-17 |
| IE861833L (en) | 1987-01-09 |
| CN86105309A (zh) | 1987-01-14 |
| EP0208510A2 (en) | 1987-01-14 |
| AU5984786A (en) | 1987-04-09 |
| JPH0610193B2 (ja) | 1994-02-09 |
| NO862750D0 (no) | 1986-07-08 |
| JPS6226269A (ja) | 1987-02-04 |
| EP0208510B1 (en) | 1991-09-11 |
| HU198015A (en) | 1989-07-28 |
| FI862882A (fi) | 1987-01-10 |
| EP0208510A3 (en) | 1988-03-02 |
| HUT41386A (en) | 1987-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GR861760B (en) | 1-substituted oxindole-3-carboxamides as anti-inflammatory and analgesic agents | |
| AU6844790A (en) | Novel a-nor-steriod-3-carboxylic acid derivatives | |
| AU6360886A (en) | Acrylic acid amides | |
| AU6822887A (en) | Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same | |
| AU556948B2 (en) | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds | |
| EP0279466A3 (en) | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | |
| IT1200852B (it) | Procedimento e dispositivo per l'alimentazione di elementida montare | |
| AU584668B2 (en) | Novel heterocyclic amides useful as anti-inflammatory and anti-allergy agents | |
| ZA865019B (en) | 1-substituted oxindole-3-carboxamides as antiinflammatory and analgesic agents | |
| EP0204344A3 (en) | Sialosylcerebrosides and a preparation method thereof | |
| AU1413788A (en) | Dihydropyridinamides process for their preparation, and their use in medicaments | |
| PT82190A (en) | Continuous process for the crystalisation of fructose and appararus for the application thereof | |
| AU8144687A (en) | Peptides | |
| AU2227288A (en) | Acrylic acid amides | |
| AU2700988A (en) | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | |
| EP0284069A3 (en) | Benzopyranopyridineacetic acid ester compounds and their pharmaceutical uses | |
| NZ211052A (en) | 1,3-disubstituted-2-oxindoles as analgesic and anti-inflammatory agents | |
| AU573961B2 (en) | Artist's palette | |
| PL256906A2 (en) | Inoculant for ferrous alloys |