FI862882A0 - 1-substituerade oxindol-3 -karboxiamider som antiinflammatoriska och vaerkstillande medel. - Google Patents

1-substituerade oxindol-3 -karboxiamider som antiinflammatoriska och vaerkstillande medel.

Info

Publication number
FI862882A0
FI862882A0 FI862882A FI862882A FI862882A0 FI 862882 A0 FI862882 A0 FI 862882A0 FI 862882 A FI862882 A FI 862882A FI 862882 A FI862882 A FI 862882A FI 862882 A0 FI862882 A0 FI 862882A0
Authority
FI
Finland
Prior art keywords
vaerkstillande
carboxiamider
antiinflammatoriska
substituerade
oxindol
Prior art date
Application number
FI862882A
Other languages
English (en)
Other versions
FI862882A (fi
Inventor
Saul Bernard Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/825,017 external-priority patent/US4678802A/en
Application filed by Pfizer filed Critical Pfizer
Publication of FI862882A0 publication Critical patent/FI862882A0/fi
Publication of FI862882A publication Critical patent/FI862882A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI862882A 1985-07-09 1986-07-08 1-substituerade oxindol-3 -karboxiamider som antiinflammatoriska och vaerkstillande medel. FI862882A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75320085A 1985-07-09 1985-07-09
US82129686A 1986-01-22 1986-01-22
US06/825,017 US4678802A (en) 1985-07-09 1986-01-31 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents

Publications (2)

Publication Number Publication Date
FI862882A0 true FI862882A0 (fi) 1986-07-08
FI862882A FI862882A (fi) 1987-01-10

Family

ID=27419443

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862882A FI862882A (fi) 1985-07-09 1986-07-08 1-substituerade oxindol-3 -karboxiamider som antiinflammatoriska och vaerkstillande medel.

Country Status (19)

Country Link
EP (1) EP0208510B1 (fi)
JP (1) JPH0610193B2 (fi)
CN (1) CN86105309A (fi)
AT (1) ATE67185T1 (fi)
AU (1) AU566065B2 (fi)
CA (1) CA1286663C (fi)
DE (1) DE3681358D1 (fi)
DK (1) DK324286A (fi)
ES (2) ES2001855A6 (fi)
FI (1) FI862882A (fi)
GR (1) GR861760B (fi)
HU (2) HU198015A (fi)
IE (1) IE58566B1 (fi)
IL (1) IL79356A (fi)
NO (1) NO862750L (fi)
NZ (1) NZ216788A (fi)
PH (1) PH22641A (fi)
PT (1) PT82931B (fi)
YU (2) YU45346B (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2655344B1 (fr) * 1989-12-06 1992-04-03 Sanofi Sa Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.
IE68593B1 (en) * 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
WO1991009598A1 (en) * 1990-01-05 1991-07-11 Pfizer Inc. Azaoxindole derivatives
FR2677356B1 (fr) * 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.
JPH08288983A (ja) * 1995-04-17 1996-11-01 Tokyo Tsuuki:Kk リンガ回路
US6306851B1 (en) 1999-05-04 2001-10-23 American Home Products Corporation Cyclocarbamate and cyclic amide derivatives
US6399593B1 (en) 1999-05-04 2002-06-04 Wyeth Cyclic regimens using cyclic urea and cyclic amide derivatives
US6462032B1 (en) 1999-05-04 2002-10-08 Wyeth Cyclic regimens utilizing indoline derivatives
US6369056B1 (en) 1999-05-04 2002-04-09 American Home Products Corporation Cyclic urea and cyclic amide derivatives
US6380178B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6339098B1 (en) 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
US6380235B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Benzimidazolones and analogues
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6423699B1 (en) 1999-05-04 2002-07-23 American Home Products Corporation Combination therapies using benzimidazolones
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6498154B1 (en) 1999-05-04 2002-12-24 Wyeth Cyclic regimens using quinazolinone and benzoxazine derivatives
US6358947B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6329416B1 (en) 1999-05-04 2001-12-11 American Home Products Corporation Combination regimens using 3,3-substituted indoline derivatives
US6319912B1 (en) 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6417214B1 (en) 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
AU2001272757A1 (en) 2000-07-19 2002-01-30 Ube Industries Ltd. Process for producing 5-fluorooxyindole and for producing intermediate therefor
US7186745B2 (en) 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
JP4770826B2 (ja) * 2007-11-22 2011-09-14 大日本印刷株式会社 2−オキシインドール誘導体の製造法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3749731A (en) 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US3882236A (en) 1973-12-26 1975-05-06 Lilly Co Eli Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
IE58566B1 (en) 1993-10-06
ATE67185T1 (de) 1991-09-15
DK324286A (da) 1987-01-10
AU5984786A (en) 1987-04-09
CA1286663C (en) 1991-07-23
HU198015A (en) 1989-07-28
EP0208510A3 (en) 1988-03-02
DK324286D0 (da) 1986-07-08
FI862882A (fi) 1987-01-10
PT82931B (pt) 1989-01-30
YU45346B (en) 1992-05-28
ES2009227A6 (es) 1989-09-16
IL79356A0 (en) 1986-10-31
ES2001855A6 (es) 1988-07-01
NZ216788A (en) 1988-10-28
IE861833L (en) 1987-01-09
PH22641A (en) 1988-10-28
PT82931A (en) 1986-08-01
EP0208510A2 (en) 1987-01-14
AU566065B2 (en) 1987-10-08
EP0208510B1 (en) 1991-09-11
YU114487A (en) 1988-02-29
NO862750L (no) 1987-01-12
YU120386A (en) 1988-02-29
DE3681358D1 (de) 1991-10-17
IL79356A (en) 1990-03-19
JPS6226269A (ja) 1987-02-04
NO862750D0 (no) 1986-07-08
HUT41386A (en) 1987-04-28
JPH0610193B2 (ja) 1994-02-09
GR861760B (en) 1986-11-10
CN86105309A (zh) 1987-01-14

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: PFIZER INC.