GR74546B - - Google Patents

Info

Publication number
GR74546B
GR74546B GR65234A GR810165234A GR74546B GR 74546 B GR74546 B GR 74546B GR 65234 A GR65234 A GR 65234A GR 810165234 A GR810165234 A GR 810165234A GR 74546 B GR74546 B GR 74546B
Authority
GR
Greece
Prior art keywords
sub
sar
tyr
glu
lys
Prior art date
Application number
GR65234A
Other languages
English (en)
Inventor
George Heavner
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22576099&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR74546(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of GR74546B publication Critical patent/GR74546B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compounds Of Unknown Constitution (AREA)
GR65234A 1980-06-17 1981-06-12 GR74546B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/160,241 US4298523A (en) 1980-06-17 1980-06-17 Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R

Publications (1)

Publication Number Publication Date
GR74546B true GR74546B (el) 1984-06-29

Family

ID=22576099

Family Applications (1)

Application Number Title Priority Date Filing Date
GR65234A GR74546B (el) 1980-06-17 1981-06-12

Country Status (19)

Country Link
US (1) US4298523A (el)
EP (3) EP0042291B1 (el)
JP (3) JPS5728036A (el)
AT (2) ATE24183T1 (el)
AU (3) AU563303B2 (el)
CA (6) CA1188297A (el)
DE (2) DE3175701D1 (el)
DK (3) DK151968C (el)
ES (3) ES8207513A1 (el)
FI (1) FI79329C (el)
GR (1) GR74546B (el)
IE (3) IE62213B1 (el)
IL (7) IL63108A (el)
NO (3) NO161744C (el)
NZ (1) NZ197294A (el)
PH (2) PH16501A (el)
PT (1) PT73201B (el)
YU (1) YU45852B (el)
ZA (1) ZA814061B (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4369137A (en) * 1980-06-17 1983-01-18 Ortho Pharmaceutical Corporation N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
DE3401545A1 (de) * 1983-08-03 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue peptide mit immunstimulierender wirkung, verfahren zu deren herstellung und deren verwendung
US4505853A (en) * 1983-11-18 1985-03-19 Ortho Pharmaceutical Corporation Enzyme-resistant immunomodulatory peptides
WO1986004334A1 (en) * 1985-01-18 1986-07-31 MERCK Patent Gesellschaft mit beschränkter Haftung Immunoregulatory peptides
US4749690A (en) * 1986-01-27 1988-06-07 Ortho Pharmaceutical Corporation Treatment of allergy with thymopentin
US4732970A (en) * 1986-06-13 1988-03-22 American Cyanamid Company Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones
US5200506A (en) * 1987-03-19 1993-04-06 Eniricerche S.P.A. Process for preparing new thymopentin retro-inverso analogs and fragments thereof and the intermediates obtained therein
HU199878B (en) * 1987-06-19 1990-03-28 Berlin Chemie Veb Process for producing acylated splenopentynes and pharmaceutical compositions comprising such compounds as active ingredient
US5656601A (en) * 1987-06-19 1997-08-12 Berlin-Chemie Ag Acylated splenopentins, methods for their synthesis and their use
FR2622587B1 (fr) * 1987-10-30 1990-12-21 Inst Vaisseaux Sang Peptide lysyl-arginyl-aspartyl-serine et ses applications en tant que medicament, notamment antithrombotique
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
JPH01264767A (ja) * 1988-11-17 1989-10-23 G N Tool Kk 砥石自動交換ｃｎｃ工具研削盤
CN101168560B (zh) * 2006-10-23 2012-09-05 江苏正大天晴药业股份有限公司 N-取代肽酰胺，其药物组合物与用途
ES2558629T3 (es) 2008-12-29 2016-02-05 Trevena, Inc. Efectores de beta-arrestina y composiciones y métodos de uso de los mismos
AU2015213777A1 (en) 2014-02-07 2016-09-22 Trevena, Inc. Crystalline and amorphous forms of a beta-arrestin effector
US9611293B2 (en) 2014-05-19 2017-04-04 Trevena, Inc. Synthesis of beta-arrestin effectors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317559A (en) * 1963-08-23 1967-05-02 American Cyanamid Co alpha-amino acid esters of n-hydroxysuccinimide and preparation and use in peptide synthesis
DE1593830A1 (de) * 1967-05-24 1971-03-11 Akad Wissenschaften Ddr Verfahren zur Herstellung von Peptiden
US3560503A (en) * 1968-09-18 1971-02-02 Council Scient Ind Res Di-lower alkyl-substituted octahydropyrazinopyrimidinones
JPS4826010B1 (el) * 1969-11-11 1973-08-03
CH611878A5 (el) * 1974-07-04 1979-06-29 Takeda Chemical Industries Ltd
DE2544348C3 (de) * 1975-10-03 1979-12-13 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen L-Leucin-13-Motilin, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
US4190646A (en) * 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
SE446867B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
US4215112A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Tripeptides and methods
US4215111A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Peptides having ubiquitin-like activity
CA1156220A (en) * 1979-04-26 1983-11-01 George Heavner Method and composition for preparation of h-sar-lys-sar-gln-nh.sub.2
DE2938420A1 (de) * 1979-09-22 1981-04-09 Hoechst Ag, 6000 Frankfurt Neue peptide und verfahren zu ihrer herstellung
US4309340A (en) * 1980-03-31 1982-01-05 American Home Products Corporation Polypeptide compositions

Also Published As

Publication number Publication date
IL72392A (en) 1985-06-30
JPH01308297A (ja) 1989-12-12
CA1188297A (en) 1985-06-04
EP0144103A2 (en) 1985-06-12
AU4566685A (en) 1985-11-07
PH16501A (en) 1983-11-04
JPH0357118B2 (el) 1991-08-30
DK154437C (da) 1989-04-10
CA1285099C (en) 1991-06-18
DK227787D0 (da) 1987-05-04
NO164245C (no) 1990-09-12
DK263781A (da) 1981-12-18
AU4566785A (en) 1985-11-07
IE881720L (en) 1981-12-17
DE3177306D1 (de) 1994-02-10
PT73201B (en) 1983-04-26
ES503012A0 (es) 1982-10-01
NO900294D0 (no) 1990-01-22
DK154653C (da) 1989-05-01
DK154437B (da) 1988-11-14
EP0565148A2 (en) 1993-10-13
IE940518L (en) 1981-12-17
FI811883L (fi) 1981-12-18
ES512721A0 (es) 1983-02-01
EP0042291A3 (en) 1982-03-31
NO885646L (no) 1981-12-18
EP0565148A3 (el) 1994-02-09
ATE24183T1 (de) 1986-12-15
PH21622A (en) 1987-12-11
YU152881A (en) 1984-02-29
IL63108A (en) 1985-06-30
ES8304541A1 (es) 1983-03-01
IE811336L (en) 1981-12-17
DK151968C (da) 1988-09-19
JPH01308298A (ja) 1989-12-12
AU563303B2 (en) 1987-07-02
IL72394A (en) 1985-06-30
IE62614B1 (en) 1995-02-22
EP0042291B1 (en) 1986-12-10
NO885646D0 (no) 1988-12-20
DK151968B (da) 1988-01-18
DE3177306T2 (de) 1994-06-30
CA1282550C (en) 1991-04-02
NO161744C (no) 1989-09-20
NO161744B (no) 1989-06-12
JPS5728036A (en) 1982-02-15
IE62213B1 (en) 1995-01-11
NZ197294A (en) 1984-12-14
NO164245B (no) 1990-06-05
CA1315042C (en) 1993-03-23
NO166532B (no) 1991-04-29
DK415485D0 (da) 1985-09-12
DK227787A (da) 1987-05-04
NO812035L (no) 1981-12-18
IL72394A0 (en) 1984-11-30
DK415485A (da) 1985-09-12
IL63108A0 (en) 1981-09-13
FI79329C (fi) 1989-12-11
ZA814061B (en) 1983-01-26
IL72392A0 (en) 1984-11-30
DE3175701D1 (en) 1987-01-22
IL72393A0 (en) 1984-11-30
PT73201A (en) 1981-07-01
US4298523A (en) 1981-11-03
ATE99327T1 (de) 1994-01-15
JPH0355480B2 (el) 1991-08-23
CA1315040C (en) 1993-03-23
FI79329B (fi) 1989-08-31
ES8303298A1 (es) 1983-02-01
EP0144103B1 (en) 1993-12-29
IL72393A (en) 1985-06-30
AU562808B2 (en) 1987-06-18
DK154653B (da) 1988-12-05
CA1315041C (en) 1993-03-23
AU4566885A (en) 1985-11-07
JPH0354957B2 (el) 1991-08-21
ES8207513A1 (es) 1982-10-01
NO166532C (no) 1991-08-07
YU45852B (sh) 1992-09-07
AU562807B2 (en) 1987-06-18
EP0144103A3 (en) 1988-08-10
NO900294L (no) 1981-12-18
EP0042291A2 (en) 1981-12-23
ES512722A0 (es) 1983-03-01

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