GR3035351T3 - Cyclic peptide anti-fungal agents - Google Patents

Cyclic peptide anti-fungal agents

Info

Publication number
GR3035351T3
GR3035351T3 GR20010400176T GR20010400176T GR3035351T3 GR 3035351 T3 GR3035351 T3 GR 3035351T3 GR 20010400176 T GR20010400176 T GR 20010400176T GR 20010400176 T GR20010400176 T GR 20010400176T GR 3035351 T3 GR3035351 T3 GR 3035351T3
Authority
GR
Greece
Prior art keywords
hydrogen
chem
alkyl
benzyl
independently
Prior art date
Application number
GR20010400176T
Other languages
English (en)
Inventor
Michael John Rodriguez
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3035351T3 publication Critical patent/GR3035351T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GR20010400176T 1995-07-25 2001-02-01 Cyclic peptide anti-fungal agents GR3035351T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/506,790 US5629289A (en) 1995-07-25 1995-07-25 Cyclic peptide antifungal agents

Publications (1)

Publication Number Publication Date
GR3035351T3 true GR3035351T3 (en) 2001-05-31

Family

ID=24016022

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400176T GR3035351T3 (en) 1995-07-25 2001-02-01 Cyclic peptide anti-fungal agents

Country Status (13)

Country Link
US (1) US5629289A (el)
EP (1) EP0757058B1 (el)
JP (1) JPH11510165A (el)
AT (1) ATE197460T1 (el)
AU (1) AU6593896A (el)
CA (1) CA2227364A1 (el)
DE (1) DE69610880T2 (el)
DK (1) DK0757058T3 (el)
ES (1) ES2151638T3 (el)
GR (1) GR3035351T3 (el)
PT (1) PT757058E (el)
SI (1) SI0757058T1 (el)
WO (1) WO1997005163A1 (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6384013B1 (en) * 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
WO1996015142A1 (en) * 1994-11-15 1996-05-23 Eli Lilly And Company Process for performing retro-aldol reaction
US6146872A (en) * 1996-06-13 2000-11-14 Fukisawa Pharmaceutical Co., Ltd. Cyclic lipopeptide acylase
WO1999040108A1 (en) * 1998-02-09 1999-08-12 Fujisawa Pharmaceutical Co., Ltd. New compound
US6323176B1 (en) * 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
WO2000011023A2 (en) 1998-08-20 2000-03-02 Eli Lilly And Company Ring modified cyclic peptide analogs
DK1137663T3 (da) 1998-12-09 2007-01-08 Lilly Co Eli Oprensning af Echinocandin-cyclopeptidforbindelser
AU2189500A (en) * 1998-12-16 2000-07-03 Eli Lilly And Company Cyclic peptide antifungal agents having a sugar substituent
BR0008712A (pt) 1999-03-03 2001-12-26 Lilly Co Eli Complexos equinocandina/carboidrato
CN100335122C (zh) * 1999-03-03 2007-09-05 伊莱利利公司 含有成胶束表面活性剂的棘白菌素药物制剂
KR20020002476A (ko) 1999-03-03 2002-01-09 피터 지. 스트링거 결정질 에키노칸딘 암모늄염의 형성 및 음이온 교환
CN1345230A (zh) * 1999-03-03 2002-04-17 伊莱利利公司 口服ecb药物制剂和药物组合物的制备方法
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260214A (en) * 1988-07-19 1993-11-09 Takara Shuzo Co. Aureobasidium pullulans which produces antibiotic R106
US5057493A (en) * 1988-07-19 1991-10-15 Takara Shuzo Co., Ltd. Novel antibiotics r106
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
JPH0826071B2 (ja) * 1989-07-11 1996-03-13 寶酒造株式会社 抗真菌抗生物質ｒ１０６誘導体
JP2639737B2 (ja) * 1990-01-23 1997-08-13 寳酒造株式会社 新規ｒ１０６類化合物
US5059540A (en) * 1990-08-13 1991-10-22 City Of Hope Sequential C-terminal degradation of peptides and proteins using cleaving reagents such as sodium trimethylsilanolate or trimethylamine N-oxide
US5159059A (en) * 1990-05-29 1992-10-27 Merck & Co., Inc. Process for reduction of certain cyclohexapeptide compounds
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Peptides, of antibiotics, processes for their preparation and pharmaceutical preparations containing them
IL105048A (en) * 1992-03-19 2001-06-14 Eli Lilly And Company U S Antifungal substances of the cyclic peptide type and a process for their preparation
JP3480848B2 (ja) * 1992-06-19 2003-12-22 タカラバイオ株式会社 環状ペプチドの合成方法
US6268338B1 (en) * 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
AU7874494A (en) * 1993-09-22 1995-04-10 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
WO1996015142A1 (en) * 1994-11-15 1996-05-23 Eli Lilly And Company Process for performing retro-aldol reaction

Also Published As

Publication number Publication date
ES2151638T3 (es) 2001-01-01
DE69610880D1 (de) 2000-12-14
EP0757058A1 (en) 1997-02-05
US5629289A (en) 1997-05-13
ATE197460T1 (de) 2000-11-11
SI0757058T1 (en) 2001-04-30
CA2227364A1 (en) 1997-02-13
EP0757058B1 (en) 2000-11-08
WO1997005163A1 (en) 1997-02-13
JPH11510165A (ja) 1999-09-07
DK0757058T3 (da) 2000-12-27
AU6593896A (en) 1997-02-26
PT757058E (pt) 2001-04-30
DE69610880T2 (de) 2001-05-10

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