GR3034922T3 - Thiazoline derivative. - Google Patents
Thiazoline derivative.Info
- Publication number
- GR3034922T3 GR3034922T3 GR20000402629T GR20000402629T GR3034922T3 GR 3034922 T3 GR3034922 T3 GR 3034922T3 GR 20000402629 T GR20000402629 T GR 20000402629T GR 20000402629 T GR20000402629 T GR 20000402629T GR 3034922 T3 GR3034922 T3 GR 3034922T3
- Authority
- GR
- Greece
- Prior art keywords
- aralkyl
- alkoxycarbonyl
- represent
- alkyl
- phenyl
- Prior art date
Links
- 150000003549 thiazolines Chemical class 0.000 title abstract 2
- -1 cyano, carbamoyl Chemical group 0.000 abstract 4
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000008485 antagonism Effects 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 108010012088 Fibrinogen Receptors Proteins 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 230000021164 cell adhesion Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000004283 imidazolin-2-yl group Chemical group [H]N1C(*)=NC([H])([H])C1([H])[H] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18833592 | 1992-07-15 | ||
| JP31840292 | 1992-11-27 | ||
| PCT/JP1993/000937 WO1994002472A1 (en) | 1992-07-15 | 1993-07-08 | Thiazoline derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3034922T3 true GR3034922T3 (en) | 2001-02-28 |
Family
ID=26504855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20000402629T GR3034922T3 (en) | 1992-07-15 | 2000-11-28 | Thiazoline derivative. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0649843B1 (el) |
| JP (1) | JP3079570B2 (el) |
| KR (1) | KR100267883B1 (el) |
| AT (1) | ATE196137T1 (el) |
| AU (1) | AU666568B2 (el) |
| CA (1) | CA2140006A1 (el) |
| DE (1) | DE69329385T2 (el) |
| DK (1) | DK0649843T3 (el) |
| ES (1) | ES2151511T3 (el) |
| GR (1) | GR3034922T3 (el) |
| PT (1) | PT649843E (el) |
| WO (1) | WO1994002472A1 (el) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4303676A1 (de) * | 1993-02-09 | 1994-08-11 | Bayer Ag | 1-Aryltriazolin(thi)one |
| US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
| US5563158A (en) * | 1993-12-28 | 1996-10-08 | The Dupont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
| KR100318785B1 (ko) * | 1994-01-14 | 2002-04-22 | 우에하라 아끼라 | 티아졸리딘유도체 |
| EP0765875A1 (en) * | 1994-06-13 | 1997-04-02 | Taisho Pharmaceutical Co. Ltd | Thiazoline derivative |
| ZA963391B (en) * | 1995-05-24 | 1997-10-29 | Du Pont Merck Pharma | Isoxazoline fibrinogen receptor antagonists. |
| CN1066451C (zh) * | 1995-07-07 | 2001-05-30 | 大正制药株式会社 | 噻唑啉衍生物及其组合物和用途 |
| AU698384B2 (en) * | 1995-07-07 | 1998-10-29 | Taisho Pharmaceutical Co., Ltd. | Thiazoline derivatives |
| AU6318996A (en) * | 1995-07-07 | 1997-02-10 | Taisho Pharmaceutical Co., Ltd. | 4-alkylthiazoline derivatives |
| AU6369196A (en) * | 1995-07-13 | 1997-02-10 | Taisho Pharmaceutical Co., Ltd. | 4-(substituted aminomethyl)thiazoline derivatives |
| AR012443A1 (es) * | 1997-04-16 | 2000-10-18 | Uriach & Cia Sa J | Nuevas carboxamidas como inhibidores de la agregacion plaquetaria, procedimiento para su preparacion, composiciones farmaceuticas que loscontienen y uso de los mismos en la manufactura de medicamentos |
| AU735144B2 (en) * | 1997-07-23 | 2001-07-05 | Yamanouchi Pharmaceutical Co., Ltd. | Novel hexahydro-1,4-diazepine derivatives or their salts |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1197259B (it) * | 1986-09-23 | 1988-11-30 | Valeas Spa | Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi |
| JPH0250148A (ja) * | 1988-05-16 | 1990-02-20 | Konica Corp | 熱現像カラー感光材料 |
-
1993
- 1993-07-08 JP JP06504343A patent/JP3079570B2/ja not_active Expired - Fee Related
- 1993-07-08 EP EP93914969A patent/EP0649843B1/en not_active Expired - Lifetime
- 1993-07-08 KR KR1019940704760A patent/KR100267883B1/ko not_active IP Right Cessation
- 1993-07-08 CA CA002140006A patent/CA2140006A1/en not_active Abandoned
- 1993-07-08 PT PT93914969T patent/PT649843E/pt unknown
- 1993-07-08 DK DK93914969T patent/DK0649843T3/da active
- 1993-07-08 DE DE69329385T patent/DE69329385T2/de not_active Expired - Fee Related
- 1993-07-08 AT AT93914969T patent/ATE196137T1/de not_active IP Right Cessation
- 1993-07-08 ES ES93914969T patent/ES2151511T3/es not_active Expired - Lifetime
- 1993-07-08 AU AU45136/93A patent/AU666568B2/en not_active Ceased
- 1993-07-08 WO PCT/JP1993/000937 patent/WO1994002472A1/ja active IP Right Grant
-
2000
- 2000-11-28 GR GR20000402629T patent/GR3034922T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69329385T2 (de) | 2001-01-04 |
| PT649843E (pt) | 2000-12-29 |
| KR100267883B1 (ko) | 2000-10-16 |
| CA2140006A1 (en) | 1994-02-03 |
| ES2151511T3 (es) | 2001-01-01 |
| AU666568B2 (en) | 1996-02-15 |
| AU4513693A (en) | 1994-02-14 |
| JP3079570B2 (ja) | 2000-08-21 |
| ATE196137T1 (de) | 2000-09-15 |
| EP0649843A1 (en) | 1995-04-26 |
| KR950702194A (ko) | 1995-06-19 |
| DK0649843T3 (da) | 2000-10-09 |
| DE69329385D1 (de) | 2000-10-12 |
| EP0649843A4 (en) | 1995-02-22 |
| EP0649843B1 (en) | 2000-09-06 |
| WO1994002472A1 (en) | 1994-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ML | Lapse due to non-payment of fees |