IT1197259B - Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi - Google Patents

Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi

Info

Publication number
IT1197259B
IT1197259B IT21784/86A IT2178486A IT1197259B IT 1197259 B IT1197259 B IT 1197259B IT 21784/86 A IT21784/86 A IT 21784/86A IT 2178486 A IT2178486 A IT 2178486A IT 1197259 B IT1197259 B IT 1197259B
Authority
IT
Italy
Prior art keywords
heterocyclic
benzoic acids
contain
active ingredients
therapeutic composition
Prior art date
Application number
IT21784/86A
Other languages
English (en)
Other versions
IT8621784A0 (it
Inventor
V Vernareggi
F Bonifacio
M Fano
L Trabella
G Battigelli
D Montagna
Original Assignee
Valeas Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valeas Spa filed Critical Valeas Spa
Priority to IT21784/86A priority Critical patent/IT1197259B/it
Publication of IT8621784A0 publication Critical patent/IT8621784A0/it
Priority to AT87113169T priority patent/ATE74915T1/de
Priority to EP87113169A priority patent/EP0261503B1/en
Priority to DE8787113169T priority patent/DE3778268D1/de
Application granted granted Critical
Publication of IT1197259B publication Critical patent/IT1197259B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT21784/86A 1986-09-23 1986-09-23 Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi IT1197259B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT21784/86A IT1197259B (it) 1986-09-23 1986-09-23 Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi
AT87113169T ATE74915T1 (de) 1986-09-23 1987-09-09 Heterozyklische amidoderivate von substituierten benzoesaeuren und therapeutische zusammensetzungen, die diese als wirkstoff enthalten.
EP87113169A EP0261503B1 (en) 1986-09-23 1987-09-09 Heterocyclic amido derivatives of substituted benzoic acids and therapeutic compositions which contain them as active principle
DE8787113169T DE3778268D1 (de) 1986-09-23 1987-09-09 Heterozyklische amidoderivate von substituierten benzoesaeuren und therapeutische zusammensetzungen, die diese als wirkstoff enthalten.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21784/86A IT1197259B (it) 1986-09-23 1986-09-23 Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi

Publications (2)

Publication Number Publication Date
IT8621784A0 IT8621784A0 (it) 1986-09-23
IT1197259B true IT1197259B (it) 1988-11-30

Family

ID=11186793

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21784/86A IT1197259B (it) 1986-09-23 1986-09-23 Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che li contengono come principi attivi

Country Status (4)

Country Link
EP (1) EP0261503B1 (it)
AT (1) ATE74915T1 (it)
DE (1) DE3778268D1 (it)
IT (1) IT1197259B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874864A (en) * 1988-05-24 1989-10-17 Pfizer Inc. Benzamide protease inhibitors
DE69329385T2 (de) * 1992-07-15 2001-01-04 Taisho Pharmaceutical Co., Ltd. Thiazolin-derivate
US5478945A (en) * 1992-07-15 1995-12-26 Taisho Pharmaceutical Co., Ltd. Thiazoline derivatives
GB9823871D0 (en) 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
WO2001062718A1 (en) * 2000-02-25 2001-08-30 Japan Tobacco, Inc. Benzamide derivative and use thereof
EP1724270A3 (en) 2001-07-19 2007-01-03 Pfizer Italia S.r.l. Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2401522A (en) * 1942-04-17 1946-06-04 Firm Sandoz Ltd Aromatic carboxylic acid amides and a process for their manufacture
US4187232A (en) * 1975-06-05 1980-02-05 Lilly Industries Limited Acylamino derivatives

Also Published As

Publication number Publication date
IT8621784A0 (it) 1986-09-23
DE3778268D1 (de) 1992-05-21
ATE74915T1 (de) 1992-05-15
EP0261503A1 (en) 1988-03-30
EP0261503B1 (en) 1992-04-15

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