GR3031179T3 - Prolonged-action pharmaceutical preparation. - Google Patents
Prolonged-action pharmaceutical preparation.Info
- Publication number
- GR3031179T3 GR3031179T3 GR990402272T GR990402272T GR3031179T3 GR 3031179 T3 GR3031179 T3 GR 3031179T3 GR 990402272 T GR990402272 T GR 990402272T GR 990402272 T GR990402272 T GR 990402272T GR 3031179 T3 GR3031179 T3 GR 3031179T3
- Authority
- GR
- Greece
- Prior art keywords
- prolonged
- pharmaceutical preparation
- tetrone
- azatricyclo
- methoxycyclohexyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30888592 | 1992-11-18 | ||
PCT/JP1993/001672 WO1994010981A1 (en) | 1992-11-18 | 1993-11-11 | Prolonged-action pharmaceutical preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3031179T3 true GR3031179T3 (en) | 1999-12-31 |
Family
ID=17986438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR990402272T GR3031179T3 (en) | 1992-11-18 | 1999-09-08 | Prolonged-action pharmaceutical preparation. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5601844A (el) |
EP (1) | EP0669127B1 (el) |
JP (1) | JP3520517B2 (el) |
CN (1) | CN1093571A (el) |
AT (1) | ATE183083T1 (el) |
AU (1) | AU5434094A (el) |
DE (1) | DE69326015T2 (el) |
DK (1) | DK0669127T3 (el) |
ES (1) | ES2134860T3 (el) |
GR (1) | GR3031179T3 (el) |
WO (1) | WO1994010981A1 (el) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06345646A (ja) * | 1993-06-08 | 1994-12-20 | Fujisawa Pharmaceut Co Ltd | ローション剤 |
US5869079A (en) * | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
US20060280774A1 (en) * | 1995-06-02 | 2006-12-14 | Allergan, Inc. | Compositions and methods for treating glaucoma |
US5910492A (en) * | 1995-06-05 | 1999-06-08 | Takeda Chemical Industries, Ltd. | Osteogenic promoting pharmaceutical composition |
CA2232378C (en) | 1995-09-19 | 2009-04-14 | Fujisawa Pharmaceutical Co., Ltd. | Aerosol compositions |
TW426516B (en) | 1996-12-06 | 2001-03-21 | Fujisawa Pharmaceutical Co | An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds |
US5849800A (en) * | 1997-03-28 | 1998-12-15 | The Penn State Research Foundation | Use of amantadine for treatment of Hepatitis C |
US6127520A (en) * | 1997-04-15 | 2000-10-03 | Regents Of The University Of Michigan | Compositions and methods for the inhibition of neurotransmitter uptake of synaptic vesicles |
US6113738A (en) * | 1998-03-16 | 2000-09-05 | Nalco Chemical Company | Use of additives to breakdown and stabilize wax during fiber recycle |
EP1064082B1 (en) | 1998-03-16 | 2004-06-02 | Nalco Company | Contaminant dispersants useful in recycling of treated containers |
TWI235068B (en) * | 1998-03-26 | 2005-07-01 | Fujisawa Pharmaceutical Co | Sustained-release pharmaceutical composition |
AU6047099A (en) | 1998-09-24 | 2000-04-10 | Boston Medical Center Corporation | Compositions and methods for the treatment of chronic lymphocytic leukemia |
US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
US6726918B1 (en) | 2000-07-05 | 2004-04-27 | Oculex Pharmaceuticals, Inc. | Methods for treating inflammation-mediated conditions of the eye |
US6699493B2 (en) | 2000-11-29 | 2004-03-02 | Oculex Pharmaceuticals, Inc. | Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
CA2498191C (en) * | 2002-09-18 | 2012-04-10 | Trustees Of The University Of Pennsylvania | Method of inhibiting choroidal neovascularization |
US20050048099A1 (en) | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
SI1663217T1 (sl) * | 2003-08-29 | 2010-10-29 | Lifecycle Pharma As | Trdne disperzije, ki vsebujejo takrolimus |
EP1663216B1 (en) * | 2003-08-29 | 2011-11-02 | Veloxis Pharmaceuticals A/S | Modified release compositions comprising tacrolimus |
CN102144961A (zh) * | 2003-09-18 | 2011-08-10 | 参天制药株式会社 | 经巩膜递送 |
US20050244469A1 (en) * | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
US8663639B2 (en) * | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
US8637070B2 (en) * | 2005-02-09 | 2014-01-28 | Santen Pharmaceutical Co., Ltd. | Rapamycin formulations and methods of their use |
US20070178138A1 (en) * | 2006-02-01 | 2007-08-02 | Allergan, Inc. | Biodegradable non-opthalmic implants and related methods |
CA2635797C (en) | 2006-02-09 | 2015-03-31 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
US8222271B2 (en) | 2006-03-23 | 2012-07-17 | Santen Pharmaceutical Co., Ltd. | Formulations and methods for vascular permeability-related diseases or conditions |
US8802128B2 (en) * | 2006-06-23 | 2014-08-12 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
US20070298073A1 (en) * | 2006-06-23 | 2007-12-27 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
US20080265343A1 (en) * | 2007-04-26 | 2008-10-30 | International Business Machines Corporation | Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof |
LT2167033T (lt) | 2007-05-30 | 2017-08-10 | Veloxis Pharmaceuticals A/S | Kartą per dieną vartojama geriamoji vaisto forma, apimanti takrolimą |
US8222272B2 (en) | 2008-04-11 | 2012-07-17 | Roxane Laboratories, Inc. | Pharmaceutical formulation and process comprising a solid dispersion of macrolide (tacrolimus) |
TWI510238B (zh) | 2010-02-17 | 2015-12-01 | Lifecycle Pharma As | 穩定化他克莫司(tacrolimus)組合物 |
AR101476A1 (es) | 2014-08-07 | 2016-12-21 | Acerta Pharma Bv | Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8430455D0 (en) * | 1984-12-03 | 1985-01-09 | Fujisawa Pharmaceutical Co | Fr-900506 substance |
GB8608080D0 (en) * | 1986-04-02 | 1986-05-08 | Fujisawa Pharmaceutical Co | Solid dispersion composition |
JPS63122620A (ja) * | 1986-11-12 | 1988-05-26 | Sanraku Inc | ポリ乳酸マイクロスフエア及びその製造方法 |
EP0346427B1 (en) * | 1987-12-09 | 1995-03-29 | FISONS plc | Macrocyclic compounds |
CA2012978C (en) * | 1990-02-13 | 2002-02-26 | Thomas E. Starzl | Treatment of hepatic diseases using fk 506 and related compounds |
US5196437A (en) * | 1990-02-13 | 1993-03-23 | Fujisawa Pharmaceutical Company, Ltd. | Method for treating hepatic diseases and regenerating liver tissue using FK 506 and related compounds |
US5260301A (en) * | 1990-03-01 | 1993-11-09 | Fujisawa Pharmaceutical Co., Ltd. | Pharmaceutical solution containing FK-506 |
JPH0449232A (ja) * | 1990-06-15 | 1992-02-18 | Fujisawa Pharmaceut Co Ltd | 懸濁用組成物または懸濁液並びにそれらの製造法 |
ES2099112T3 (es) * | 1990-09-04 | 1997-05-16 | Fujisawa Pharmaceutical Co | Pomadas que contienen un compuesto triciclico. |
IE65341B1 (en) * | 1990-11-08 | 1995-10-18 | Fujisawa Pharmaceutical Co | Suspensions containing tricyclic compounds |
-
1993
- 1993-11-11 EP EP93924826A patent/EP0669127B1/en not_active Expired - Lifetime
- 1993-11-11 DE DE69326015T patent/DE69326015T2/de not_active Expired - Lifetime
- 1993-11-11 DK DK93924826T patent/DK0669127T3/da active
- 1993-11-11 ES ES93924826T patent/ES2134860T3/es not_active Expired - Lifetime
- 1993-11-11 WO PCT/JP1993/001672 patent/WO1994010981A1/ja active IP Right Grant
- 1993-11-11 AT AT93924826T patent/ATE183083T1/de not_active IP Right Cessation
- 1993-11-11 AU AU54340/94A patent/AU5434094A/en not_active Abandoned
- 1993-11-11 JP JP51193194A patent/JP3520517B2/ja not_active Expired - Fee Related
- 1993-11-11 US US08/424,498 patent/US5601844A/en not_active Expired - Lifetime
- 1993-11-17 CN CN93121437A patent/CN1093571A/zh active Pending
-
1999
- 1999-09-08 GR GR990402272T patent/GR3031179T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN1093571A (zh) | 1994-10-19 |
EP0669127A1 (en) | 1995-08-30 |
DE69326015T2 (de) | 2000-02-03 |
JP3520517B2 (ja) | 2004-04-19 |
DK0669127T3 (da) | 1999-12-06 |
ES2134860T3 (es) | 1999-10-16 |
DE69326015D1 (de) | 1999-09-16 |
US5601844A (en) | 1997-02-11 |
EP0669127B1 (en) | 1999-08-11 |
EP0669127A4 (en) | 1995-11-02 |
WO1994010981A1 (en) | 1994-05-26 |
ATE183083T1 (de) | 1999-08-15 |
AU5434094A (en) | 1994-06-08 |
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GR3031179T3 (en) | Prolonged-action pharmaceutical preparation. | |
IL100011A0 (en) | Suspendible pharmaceutical composition containing a tricyclic compound and processes for the preparation thereof | |
DK0474126T3 (el) | ||
IL94971A0 (en) | Aqueous pharmaceutical composition containing a tricyclic compound and processes for the preparation thereof | |
DE3777223D1 (de) | Feste dispersion der substanz fr-900506. | |
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