GR3030437T3 - Water-soluble nimesulide salt, and uses thereof for the treatment of inflammations - Google Patents
Water-soluble nimesulide salt, and uses thereof for the treatment of inflammationsInfo
- Publication number
- GR3030437T3 GR3030437T3 GR990401524T GR990401524T GR3030437T3 GR 3030437 T3 GR3030437 T3 GR 3030437T3 GR 990401524 T GR990401524 T GR 990401524T GR 990401524 T GR990401524 T GR 990401524T GR 3030437 T3 GR3030437 T3 GR 3030437T3
- Authority
- GR
- Greece
- Prior art keywords
- pct
- inflammations
- treatment
- water
- soluble
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE9400582A BE1008307A3 (fr) | 1994-06-16 | 1994-06-16 | Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation. |
PCT/BE1995/000055 WO1995034533A1 (fr) | 1994-06-16 | 1995-06-16 | Sel de nimesulide hydrosoluble et leurs utilisations pour le traitement des affections inflammatoires |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3030437T3 true GR3030437T3 (en) | 1999-09-30 |
Family
ID=3888206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR990401524T GR3030437T3 (en) | 1994-06-16 | 1999-06-09 | Water-soluble nimesulide salt, and uses thereof for the treatment of inflammations |
Country Status (19)
Country | Link |
---|---|
US (1) | US5756546A (el) |
EP (1) | EP0714386B1 (el) |
JP (1) | JPH09503002A (el) |
AT (1) | ATE177421T1 (el) |
AU (1) | AU693901B2 (el) |
BE (1) | BE1008307A3 (el) |
CA (1) | CA2169747A1 (el) |
CZ (1) | CZ289746B6 (el) |
DE (1) | DE69508192T2 (el) |
DK (1) | DK0714386T3 (el) |
ES (1) | ES2132678T3 (el) |
GR (1) | GR3030437T3 (el) |
HU (1) | HUT76475A (el) |
NZ (1) | NZ288150A (el) |
PL (1) | PL179789B1 (el) |
RU (1) | RU2151764C1 (el) |
SK (1) | SK281496B6 (el) |
UA (1) | UA42734C2 (el) |
WO (1) | WO1995034533A1 (el) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP9601442A3 (en) * | 1995-07-25 | 1999-03-29 | Panacea Biotec Ltd | Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them |
SI9620016B (sl) * | 1995-10-05 | 1999-06-30 | Helsinn Healthcare Sa | Antiinflamatorno sredstvo za zunanjo rabo |
NO965193L (no) | 1995-12-08 | 1997-06-09 | Seikagaku Kogyo Kk Seikagaku C | Aminalkoholderivat og fremgangsmåte for fremstilling derav |
UA57734C2 (uk) | 1996-05-07 | 2003-07-15 | Пфайзер Інк. | Комплекси включення арилгетероциклічних солей |
IN186315B (el) * | 1996-12-12 | 2001-08-04 | Panacea Biotec Ltd | |
ES2129010B1 (es) * | 1997-01-02 | 2000-01-16 | Gold Oscar | Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion. |
IT1290448B1 (it) * | 1997-04-01 | 1998-12-03 | Schiena Michele Giuseppe Di | Nimesulide sale di colina,metodo di preparazione e composizioni farmaceutiche che lo contengono |
AU718356B2 (en) * | 1998-01-12 | 2000-04-13 | Panacea Biotec Limited | A parenteral water-miscible non-intensely coloured injectable composition of non-steroidal anit-inflammatory drugs |
AU1885999A (en) * | 1998-02-17 | 1999-08-30 | Miciopharma Chemical Aktiengesellschaft | A watersoluble nimesulide adduct also for injectable use |
US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
US8236352B2 (en) * | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
CA2346001C (en) * | 1998-10-01 | 2003-12-30 | Elan Pharma International, Limited | Controlled release nanoparticulate compositions |
US20080213378A1 (en) * | 1998-10-01 | 2008-09-04 | Elan Pharma International, Ltd. | Nanoparticulate statin formulations and novel statin combinations |
US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
US20040141925A1 (en) * | 1998-11-12 | 2004-07-22 | Elan Pharma International Ltd. | Novel triamcinolone compositions |
US6969529B2 (en) * | 2000-09-21 | 2005-11-29 | Elan Pharma International Ltd. | Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers |
US6428814B1 (en) * | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
US20040156872A1 (en) * | 2000-05-18 | 2004-08-12 | Elan Pharma International Ltd. | Novel nimesulide compositions |
PE20020300A1 (es) * | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
US7198795B2 (en) | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
MY137736A (en) * | 2001-04-03 | 2009-03-31 | Pharmacia Corp | Reconstitutable parenteral composition |
BR0102252B1 (pt) * | 2001-04-10 | 2013-10-22 | Sistema de liberação controlada para antagonista do receptor AT1 da angiotensina II, composição farmacêutica e seu uso | |
ES2343405T3 (es) * | 2002-02-04 | 2010-07-30 | Elan Pharma International Ltd. | Composiciones nanoparticuladas que tienen lisozima como un estabilizador de superficie. |
US20040101566A1 (en) * | 2002-02-04 | 2004-05-27 | Elan Pharma International Limited | Novel benzoyl peroxide compositions |
JP2005521691A (ja) * | 2002-02-22 | 2005-07-21 | ファルマシア・コーポレーション | シクロデキストリン化合物及び塩化セチルピリジニウムを含有する眼科用抗菌性薬物製剤 |
JP2005520856A (ja) * | 2002-03-20 | 2005-07-14 | ファルマシア コーポレーション | 貯蔵時に安定なエプレレノン製剤 |
JP4776229B2 (ja) * | 2002-07-16 | 2011-09-21 | エラン ファーマ インターナショナル,リミティド | 安定なナノ粒子活性物質の液体投与組成物 |
CN1511828A (zh) * | 2002-12-31 | 2004-07-14 | �й������ž�����ҽѧ��ѧԺ����ҽ | 磺酰苯胺类衍生物及其医药用途 |
ITMI20041121A1 (it) * | 2004-06-03 | 2004-09-03 | Advance Holdings Ltd | Derivato della nimesulide metodo per prepararlo e composizione farmaceutica che lo comprende |
US7576222B2 (en) * | 2004-12-28 | 2009-08-18 | Wyeth | Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase |
EP1902705A1 (en) * | 2006-09-22 | 2008-03-26 | Pharmatex Italia Srl | Injectable pharmaceutical nimesulide solutions |
BE1018280A3 (fr) * | 2008-09-09 | 2010-08-03 | Squarepoint Pointcarre Sprl | Composition de nimesulide a liberation prolongee. |
BE1018279A3 (fr) * | 2008-09-09 | 2010-08-03 | Squarepoint Pointcarre Sprl | Composition de nimesulide orodispersible. |
US20120171184A1 (en) | 2010-12-31 | 2012-07-05 | Lajos Szente | Cellular hydration compositions |
JP2015044850A (ja) * | 2014-11-07 | 2015-03-12 | イーストポンド・ラボラトリーズ・リミテッド | シクロデキストリンを含有する細胞水和組成物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3840597A (en) * | 1971-02-24 | 1974-10-08 | Riker Laboratories Inc | Substituted 2-phenoxy alkane-sulfonanilides |
AR206496A1 (es) * | 1972-07-03 | 1976-07-30 | Riker Laboratories Inc | Procedimiento para la preparacion de 2-fenoxi-4-nitro-alquil o haloalquilsulfonanilidas |
US4983628A (en) * | 1983-10-27 | 1991-01-08 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
IT1248475B (it) * | 1990-05-22 | 1995-01-19 | Angeli Inst Spa | Composti di inclusione di nimesulide con ciclodestrine |
-
1994
- 1994-06-16 BE BE9400582A patent/BE1008307A3/fr not_active IP Right Cessation
-
1995
- 1995-06-16 UA UA96031021A patent/UA42734C2/uk unknown
- 1995-06-16 AT AT95922359T patent/ATE177421T1/de not_active IP Right Cessation
- 1995-06-16 AU AU27085/95A patent/AU693901B2/en not_active Ceased
- 1995-06-16 US US08/596,348 patent/US5756546A/en not_active Expired - Fee Related
- 1995-06-16 NZ NZ288150A patent/NZ288150A/en unknown
- 1995-06-16 HU HU9600654A patent/HUT76475A/hu unknown
- 1995-06-16 DK DK95922359T patent/DK0714386T3/da active
- 1995-06-16 RU RU96105706/04A patent/RU2151764C1/ru active
- 1995-06-16 PL PL95313031A patent/PL179789B1/pl unknown
- 1995-06-16 WO PCT/BE1995/000055 patent/WO1995034533A1/fr active IP Right Grant
- 1995-06-16 JP JP8501408A patent/JPH09503002A/ja active Pending
- 1995-06-16 SK SK356-96A patent/SK281496B6/sk unknown
- 1995-06-16 EP EP95922359A patent/EP0714386B1/fr not_active Expired - Lifetime
- 1995-06-16 CZ CZ1996792A patent/CZ289746B6/cs not_active IP Right Cessation
- 1995-06-16 DE DE69508192T patent/DE69508192T2/de not_active Expired - Fee Related
- 1995-06-16 ES ES95922359T patent/ES2132678T3/es not_active Expired - Lifetime
- 1995-06-16 CA CA002169747A patent/CA2169747A1/fr not_active Abandoned
-
1999
- 1999-06-09 GR GR990401524T patent/GR3030437T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HUT76475A (en) | 1997-09-29 |
PL313031A1 (en) | 1996-05-27 |
DE69508192T2 (de) | 1999-10-14 |
JPH09503002A (ja) | 1997-03-25 |
DK0714386T3 (da) | 1999-09-27 |
PL179789B1 (pl) | 2000-10-31 |
RU2151764C1 (ru) | 2000-06-27 |
NZ288150A (en) | 1998-09-24 |
UA42734C2 (uk) | 2001-11-15 |
BE1008307A3 (fr) | 1996-04-02 |
US5756546A (en) | 1998-05-26 |
EP0714386B1 (fr) | 1999-03-10 |
ES2132678T3 (es) | 1999-08-16 |
CZ289746B6 (cs) | 2002-03-13 |
AU2708595A (en) | 1996-01-05 |
EP0714386A1 (fr) | 1996-06-05 |
CZ79296A3 (en) | 1996-10-16 |
ATE177421T1 (de) | 1999-03-15 |
MX9600642A (es) | 1997-07-31 |
WO1995034533A1 (fr) | 1995-12-21 |
CA2169747A1 (fr) | 1995-12-21 |
SK281496B6 (sk) | 2001-04-09 |
DE69508192D1 (de) | 1999-04-15 |
HU9600654D0 (en) | 1996-05-28 |
SK35696A3 (en) | 1996-12-04 |
AU693901B2 (en) | 1998-07-09 |
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