GR3029835T3 - Improved lyophilized ifosfamide compositions - Google Patents
Improved lyophilized ifosfamide compositionsInfo
- Publication number
- GR3029835T3 GR3029835T3 GR990400929T GR990400929T GR3029835T3 GR 3029835 T3 GR3029835 T3 GR 3029835T3 GR 990400929 T GR990400929 T GR 990400929T GR 990400929 T GR990400929 T GR 990400929T GR 3029835 T3 GR3029835 T3 GR 3029835T3
- Authority
- GR
- Greece
- Prior art keywords
- ifosfamide compositions
- improved
- improved lyophilized
- compositions
- lyophilized ifosfamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Materials For Medical Uses (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Cosmetics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/781,436 US5227373A (en) | 1991-10-23 | 1991-10-23 | Lyophilized ifosfamide compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3029835T3 true GR3029835T3 (en) | 1999-06-30 |
Family
ID=25122737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR990400929T GR3029835T3 (en) | 1991-10-23 | 1999-03-31 | Improved lyophilized ifosfamide compositions |
Country Status (24)
Country | Link |
---|---|
US (1) | US5227373A (el) |
EP (1) | EP0538858B1 (el) |
JP (1) | JP3576180B2 (el) |
KR (1) | KR100247161B1 (el) |
CN (1) | CN1046202C (el) |
AT (1) | ATE175354T1 (el) |
AU (1) | AU658011B2 (el) |
CA (1) | CA2081061A1 (el) |
CZ (1) | CZ282445B6 (el) |
DE (1) | DE69228105T2 (el) |
DK (1) | DK0538858T3 (el) |
EG (1) | EG20114A (el) |
ES (1) | ES2125880T3 (el) |
FI (1) | FI107701B (el) |
GR (1) | GR3029835T3 (el) |
HU (2) | HU221428B (el) |
IL (1) | IL103496A (el) |
MX (1) | MX9206105A (el) |
MY (1) | MY109794A (el) |
NZ (1) | NZ244816A (el) |
RU (1) | RU2106138C1 (el) |
SK (1) | SK279869B6 (el) |
TW (1) | TW217987B (el) |
ZA (1) | ZA928104B (el) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995007083A1 (en) * | 1993-09-10 | 1995-03-16 | F.H. Faulding & Co. Limited | Ifosfamide lyophilisate composition |
US5789000A (en) * | 1994-11-14 | 1998-08-04 | Bionumerik Pharmaceuticals, Inc. | Sterile aqueous parenteral formulations of cis-diammine dichloro platinum |
DE19529057B4 (de) * | 1995-08-08 | 2007-12-13 | Baxter Healthcare S.A. | Ifosfamid-Lyophilisat-Zubereitungen |
DE19733305A1 (de) * | 1997-08-01 | 1999-02-04 | Asta Medica Ag | Pharmazeutische Zusammensetzung enthaltend Ifosfamid und Carnitin |
AU1555099A (en) * | 1997-10-13 | 1999-05-03 | Stada Arzneimittel A.G. | Liquid presentations of oxazaphosphorine-containing pharmaceutical products |
US5972912A (en) * | 1998-12-17 | 1999-10-26 | S.P. Pharmaceuticals | Method for lyophilizing ifosfamide |
US6613927B1 (en) | 2002-02-08 | 2003-09-02 | American Pharmaceutical Partners, Inc. | Sterile lyophilized ifosfamide and associated methods |
CA2476494C (en) | 2002-02-22 | 2010-04-27 | Schering Corporation | Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same |
WO2004022699A2 (en) * | 2002-09-05 | 2004-03-18 | Bharat Serums And Vaccines Ltd. | Liquid stable composition of oxazaphosphorine with mesna |
BR0316968A (pt) * | 2002-12-02 | 2005-10-25 | Bharat Serums & Vaccines Ltd | Composições estáveis, claras, aquosas de ifosfamida para administração parenteral que apresentam pouca toxicidade; processo para a preparação de composições de ifosfamida; e composições de ifosfamida e um processo para a preparação das mesmas |
US7199111B2 (en) * | 2002-12-02 | 2007-04-03 | Bharat Serums & Vaccines Ltd. | Aqueous ifosfamide compositions for parenteral administration and a process for their preparations |
SI1667655T1 (sl) * | 2003-10-01 | 2011-10-28 | Baxter Int | Nova uporaba, farmacevtski pripravki, kot tudi postopek za njihovo proizvodnjo |
TW200621240A (en) * | 2004-11-05 | 2006-07-01 | Salmedix Inc | Cancer treatments |
US8436190B2 (en) * | 2005-01-14 | 2013-05-07 | Cephalon, Inc. | Bendamustine pharmaceutical compositions |
EP1973406B1 (en) | 2005-12-28 | 2014-03-12 | Advanced Bionutrition Corporation | A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form |
US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
MX2009003197A (es) * | 2006-09-29 | 2009-05-08 | Infa Sa | Sistema de embalaje para composiciones farmaceuticas y equipo para administracion intravenosa. |
WO2008076975A1 (en) | 2006-12-18 | 2008-06-26 | Advanced Bionutrition Corporation | A dry food product containing live probiotic |
US20100210700A1 (en) * | 2007-05-08 | 2010-08-19 | Schering Corporation | Methods of treatment using intravenous formulations comprising temozolomide |
AR072777A1 (es) | 2008-03-26 | 2010-09-22 | Cephalon Inc | Formas solidas de clorhidrato de bendamustina |
EP2326306A1 (en) * | 2008-09-25 | 2011-06-01 | Cephalon, Inc. | Liquid formulations of bendamustine |
CA2749101A1 (en) * | 2009-01-15 | 2010-07-22 | Cephalon, Inc. | Novel forms of bendamustine free base |
CA2986751A1 (en) | 2009-03-27 | 2010-09-30 | Intervet International B.V. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
ES2643148T3 (es) * | 2009-05-26 | 2017-11-21 | Advanced Bionutrition Corporation | Composición en polvo seco estable que comprende microorganismos biológicamente activos y/o materiales bioactivos y métodos de producción |
US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
BR112012018839B1 (pt) | 2010-01-28 | 2020-04-14 | Advanced Bionutrition Corp | composição vítrea seca compreendendo um material bioativo |
BR112013003244B1 (pt) | 2010-08-13 | 2018-07-17 | Advanced Bionutrition Corp | composição seca estabilizante para material biológico, seu método de preparação, e formulação de carreamento oral |
ES2750749T3 (es) * | 2014-01-06 | 2020-03-27 | Auxin Surgery Sa | Composiciones de Mesna liofilizadas |
US10342769B2 (en) | 2014-11-14 | 2019-07-09 | Navinta Iii Inc | Carmustine pharmaceutical composition |
PT3328215T (pt) | 2015-07-29 | 2021-08-03 | Advanced Bionutrition Corp | Composições probióticas estáveis secas para utilizações dietéticas especiais |
JP6706988B2 (ja) * | 2016-07-20 | 2020-06-10 | 日本化薬株式会社 | ボルテゾミブを含有する医薬組成物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3732340A (en) * | 1966-07-11 | 1973-05-08 | Asta Werke Ag Chem Fab | N',o-propylene phosphoric acid ester diamides |
US4537883A (en) * | 1982-11-12 | 1985-08-27 | Mead Johnson & Company | Lyophilized cyclophosphamide |
ZA851062B (en) * | 1984-03-01 | 1985-11-27 | Asta Werke Ag Chem Fab | Salts of oxazaphosphorine derivatives and process for their production |
EP0254902B1 (de) * | 1986-07-11 | 1991-08-28 | ASTA Pharma Aktiengesellschaft | Lösungen von Oxazaphosphorinen mit verbesserter Stabilität und Verfahren zu deren Herstellung |
NO873860L (no) * | 1986-10-31 | 1988-05-02 | Asta Pharma Ag | Ifosfamid-lyofilisat og fremgangsmaate til deres fremstilling. |
DE3862595D1 (de) * | 1987-03-06 | 1991-06-06 | Asta Pharma Ag | Verfahren zur herstellung von ifosfamid mit verbesserten eigenschaften. |
ES2040394T3 (es) * | 1988-03-19 | 1993-10-16 | Asta Medica Aktiengesellschaft | Procedimiento para preparar un material liofilizado de ifosfamida y mesna. |
US5036060A (en) * | 1988-07-25 | 1991-07-30 | Fujisawa Usa, Inc. | Cyclophosphamide |
-
1991
- 1991-10-23 US US07/781,436 patent/US5227373A/en not_active Expired - Lifetime
-
1992
- 1992-10-20 KR KR1019920019270A patent/KR100247161B1/ko not_active IP Right Cessation
- 1992-10-20 ZA ZA928104A patent/ZA928104B/xx unknown
- 1992-10-20 CZ CS923176A patent/CZ282445B6/cs not_active IP Right Cessation
- 1992-10-20 NZ NZ244816A patent/NZ244816A/en not_active IP Right Cessation
- 1992-10-20 MY MYPI92001893A patent/MY109794A/en unknown
- 1992-10-20 SK SK3176-92A patent/SK279869B6/sk not_active IP Right Cessation
- 1992-10-21 HU HU9203306A patent/HU221428B/hu not_active IP Right Cessation
- 1992-10-21 CN CN92111646A patent/CN1046202C/zh not_active Expired - Fee Related
- 1992-10-21 CA CA002081061A patent/CA2081061A1/en not_active Abandoned
- 1992-10-21 IL IL10349692A patent/IL103496A/en not_active IP Right Cessation
- 1992-10-21 TW TW081108396A patent/TW217987B/zh not_active IP Right Cessation
- 1992-10-21 EG EG63992A patent/EG20114A/xx active
- 1992-10-21 AU AU27166/92A patent/AU658011B2/en not_active Ceased
- 1992-10-22 ES ES92118093T patent/ES2125880T3/es not_active Expired - Lifetime
- 1992-10-22 AT AT92118093T patent/ATE175354T1/de not_active IP Right Cessation
- 1992-10-22 FI FI924797A patent/FI107701B/fi active
- 1992-10-22 DE DE69228105T patent/DE69228105T2/de not_active Expired - Lifetime
- 1992-10-22 EP EP92118093A patent/EP0538858B1/en not_active Expired - Lifetime
- 1992-10-22 RU RU92004463A patent/RU2106138C1/ru not_active IP Right Cessation
- 1992-10-22 DK DK92118093T patent/DK0538858T3/da active
- 1992-10-22 JP JP32457092A patent/JP3576180B2/ja not_active Expired - Lifetime
- 1992-10-23 MX MX9206105A patent/MX9206105A/es unknown
-
1995
- 1995-06-20 HU HU95P/P00276P patent/HU211293A9/hu unknown
-
1999
- 1999-03-31 GR GR990400929T patent/GR3029835T3/el unknown
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