DE3884663D1 - Gefriergetrockneter, stabiler, lebendiger Herpesvirus-Impfstoff. - Google Patents

Gefriergetrockneter, stabiler, lebendiger Herpesvirus-Impfstoff.

Info

Publication number
DE3884663D1
DE3884663D1 DE88303834T DE3884663T DE3884663D1 DE 3884663 D1 DE3884663 D1 DE 3884663D1 DE 88303834 T DE88303834 T DE 88303834T DE 3884663 T DE3884663 T DE 3884663T DE 3884663 D1 DE3884663 D1 DE 3884663D1
Authority
DE
Germany
Prior art keywords
freeze
dried
stable
herpes virus
virus vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88303834T
Other languages
English (en)
Other versions
DE3884663T2 (de
Inventor
William J Mcaleer
Henry Z Markus
Robert Z Maigetter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3884663D1 publication Critical patent/DE3884663D1/de
Publication of DE3884663T2 publication Critical patent/DE3884663T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/25Varicella-zoster virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0015Combination vaccines based on measles-mumps-rubella
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE88303834T 1987-05-04 1988-04-28 Gefriergetrockneter, stabiler, lebendiger Herpesvirus-Impfstoff. Expired - Fee Related DE3884663T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4594087A 1987-05-04 1987-05-04

Publications (2)

Publication Number Publication Date
DE3884663D1 true DE3884663D1 (de) 1993-11-11
DE3884663T2 DE3884663T2 (de) 1994-04-07

Family

ID=21940663

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88303834T Expired - Fee Related DE3884663T2 (de) 1987-05-04 1988-04-28 Gefriergetrockneter, stabiler, lebendiger Herpesvirus-Impfstoff.

Country Status (16)

Country Link
EP (1) EP0290197B1 (de)
JP (1) JP2643982B2 (de)
KR (1) KR960016581B1 (de)
AT (1) ATE95427T1 (de)
AU (1) AU622110B2 (de)
CA (1) CA1324956C (de)
DE (1) DE3884663T2 (de)
DK (1) DK238688A (de)
FI (1) FI94093C (de)
HK (1) HK5997A (de)
IE (1) IE61575B1 (de)
IL (1) IL86180A (de)
NO (1) NO176163C (de)
NZ (1) NZ224419A (de)
PT (1) PT87388B (de)
ZA (1) ZA883133B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2000034A6 (es) * 1985-11-26 1987-10-01 Schweiz Serum & Impfinst Procedimiento para la preparacion de una vacuna viva contra paperas
IL120202A (en) 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
GB9808922D0 (en) 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
HUP0202537A3 (en) 1999-08-24 2004-05-28 Teva Pharma A vaccine composition and method of using the same
US6592869B2 (en) 1999-08-24 2003-07-15 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
US9132184B2 (en) 2006-11-07 2015-09-15 Sanofi Pasteur Biologics, Llc Stabilization of vaccines by lyophilization
EP2699266B1 (de) * 2011-04-21 2019-06-12 Trustees Of Tufts College Zusammensetzungen und verfahren zur stabilisierung von wirkstoffen
EP3902529A1 (de) * 2018-12-27 2021-11-03 Amgen Inc. Lyophilisierte virusformulierungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5341202B2 (de) * 1974-03-12 1978-11-01
GB1481650A (en) * 1975-05-06 1977-08-03 Merck & Co Inc Chemical processes and products
US4273762A (en) * 1979-12-03 1981-06-16 Merck & Co., Inc. Lyophilization process for live viral compositions
US4859587A (en) * 1984-06-04 1989-08-22 Institut Merieux Recombinant herpes simplex viruses, vaccines and methods
ZA874625B (en) * 1986-06-30 1988-10-26 Smith Kline Rit Stabilizers for live vaccines,process for their preparation and vaccines containing them

Also Published As

Publication number Publication date
IE881248L (en) 1988-11-04
JP2643982B2 (ja) 1997-08-25
DK238688A (da) 1988-11-05
KR960016581B1 (ko) 1996-12-16
AU1552788A (en) 1988-11-10
NO176163B (no) 1994-11-07
IL86180A (en) 1992-08-18
HK5997A (en) 1997-01-17
NO176163C (no) 1995-02-15
PT87388A (pt) 1989-05-31
EP0290197A3 (en) 1989-10-18
NO881931L (no) 1988-11-07
NZ224419A (en) 1991-03-26
PT87388B (pt) 1992-08-31
DE3884663T2 (de) 1994-04-07
JPS646220A (en) 1989-01-10
AU622110B2 (en) 1992-04-02
DK238688D0 (da) 1988-05-03
ATE95427T1 (de) 1993-10-15
CA1324956C (en) 1993-12-07
FI882041A0 (fi) 1988-05-02
ZA883133B (en) 1988-11-08
NO881931D0 (no) 1988-05-03
FI882041A (fi) 1988-11-05
KR880013575A (ko) 1988-12-21
EP0290197A2 (de) 1988-11-09
EP0290197B1 (de) 1993-10-06
IL86180A0 (en) 1988-11-15
FI94093B (fi) 1995-04-13
FI94093C (fi) 1995-07-25
IE61575B1 (en) 1994-11-16

Similar Documents

Publication Publication Date Title
DE3886073D1 (de) Gebläseanlage.
DE69016956D1 (de) Rekombinantes Truthahn-Herpesvirus und davon abgeleiteter Lebendimpfstoffvektor.
DE10299049I1 (de) Rekombinante Viren.
DE3887256D1 (de) PFBC-Kraftwerk.
RU92004463A (ru) Усовершенствованные лиофилизированные поросерамидные композиции
FI883999A0 (fi) Substituerade triazolinoner.
DE3750847D1 (de) Einrichtung zur Gefriertrocknung.
DE3884663D1 (de) Gefriergetrockneter, stabiler, lebendiger Herpesvirus-Impfstoff.
DE3851623D1 (de) Phasengesteuerter lichtablenker.
DE58901136D1 (de) Turboradialgeblaese.
DK331087A (da) Stabilisator for levende vaccine
DE3768515D1 (de) Insektentoetende n'-substituierte n-alkylcarbonyl-n'-acylhydrazine.
DE3877508D1 (de) Aliphatische ester 1,3,2-oxazaphospholidinen.
NO875038D0 (no) Konjugert vaksine.
FI854074A0 (fi) Peptid-substituerade heterocykliska immunostimulanter.
LV10051A (lv) Liofilizeta ifosfamida iegusanas veids
FI883088A (fi) Nya 3',4'-dikvaevesubstituerade epipodofyllotoxinglukosidderivat.
DK492889D0 (da) Blaeseslibeapparat
MX9206973A (es) Vacuna a base de virus del herpes bovino modificado tipo 1.
Kasilingam Tree parser
IT211539Z2 (it) Depuratore d'aria per macchine raccoglitrici di frutta secca dal terreno.
NZ186929A (en) Stabilized live virus vaccine
KR890006464U (ko) 경운기를 이용한 송풍장치
KR890013543U (ko) 산 배출용 송풍기
FI893323A (fi) Foerfarande foer braennsvetsning av ett par stycken.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee