GR3023227T3 - Process for making antimicrobial quinolonyl lactams. - Google Patents

Process for making antimicrobial quinolonyl lactams.

Info

Publication number
GR3023227T3
GR3023227T3 GR970400889T GR970400889T GR3023227T3 GR 3023227 T3 GR3023227 T3 GR 3023227T3 GR 970400889 T GR970400889 T GR 970400889T GR 970400889 T GR970400889 T GR 970400889T GR 3023227 T3 GR3023227 T3 GR 3023227T3
Authority
GR
Greece
Prior art keywords
quinolone
compound
lactam
moiety
steps
Prior art date
Application number
GR970400889T
Other languages
Greek (el)
English (en)
Inventor
Ronald Eugene White
Thomas Prosser Demuth Jr
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of GR3023227T3 publication Critical patent/GR3023227T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR970400889T 1991-10-01 1997-04-22 Process for making antimicrobial quinolonyl lactams. GR3023227T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76961591A 1991-10-01 1991-10-01
PCT/US1992/008246 WO1993007154A1 (en) 1991-10-01 1992-09-28 Process for making antimicrobial quinolonyl lactams

Publications (1)

Publication Number Publication Date
GR3023227T3 true GR3023227T3 (en) 1997-07-30

Family

ID=25085987

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970400889T GR3023227T3 (en) 1991-10-01 1997-04-22 Process for making antimicrobial quinolonyl lactams.

Country Status (22)

Country Link
US (1) US5281703A (cs)
EP (1) EP0606336B1 (cs)
KR (1) KR100253825B1 (cs)
CN (1) CN1046523C (cs)
AT (1) ATE150463T1 (cs)
AU (1) AU667837B2 (cs)
BR (1) BR9206590A (cs)
CA (1) CA2120493A1 (cs)
CZ (1) CZ73194A3 (cs)
DE (1) DE69218445T2 (cs)
DK (1) DK0606336T3 (cs)
ES (1) ES2101119T3 (cs)
FI (1) FI941490A (cs)
GR (1) GR3023227T3 (cs)
HU (1) HUT67423A (cs)
MX (1) MX9205620A (cs)
NO (1) NO304599B1 (cs)
NZ (1) NZ244557A (cs)
PT (1) PT100920B (cs)
RU (1) RU2130938C1 (cs)
SK (1) SK37594A3 (cs)
WO (1) WO1993007154A1 (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
EP0937445B1 (en) * 1993-12-28 2004-03-24 Kao Corporation Crosslinked cellulose fibers, absorbent papers and absorbent members using the same, topsheets using the same, and absorbent articles using the same
MX9700872A (es) * 1994-08-02 1997-05-31 Procter & Gamble Procedimiento para producir antimicrobianos de quinolonil-lactama y compuestos intermediarios novedosos.
NZ290721A (en) * 1994-08-02 1999-03-29 Procter & Gamble Process for making quinolone-containing antimicrobial compounds
EP0695753A1 (en) * 1994-08-05 1996-02-07 Zeneca Limited Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use
US5607928A (en) * 1994-08-05 1997-03-04 Zeneca Limited Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
EP0970065A4 (en) * 1997-11-29 2001-03-07 William L Truett ANTIBIOTICS AND THEIR PREPARATION PROCESS
US6437119B1 (en) 1998-05-07 2002-08-20 William Lawrence Truett Compounds formed from two or three antibiotics and their processes of preparation
US6947844B2 (en) * 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
US6638908B1 (en) * 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
IN191798B (cs) 2000-11-03 2004-01-03 Ranbaxy Lab Ltd
ATE257468T1 (de) * 2001-03-30 2004-01-15 Dar Al Dawa Dev And Invest Co Chinolin-4-on derivate und deren verwendung als antibiotika
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
KR20060002800A (ko) * 2003-03-05 2006-01-09 립-엑스 파마슈티칼즈, 인크. 이관능성 헤테로시클릭 화합물, 및 그의 제조 및 사용 방법
JP2007509980A (ja) * 2003-10-30 2007-04-19 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環式化合物およびそれらの化合物を調製および使用する方法
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
CN102816194A (zh) 2004-02-27 2012-12-12 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU63689A (en) * 1988-03-31 1991-06-30 Hoffmann La Roche Acyl derivatives
EP0366640B1 (en) * 1988-10-24 1999-02-03 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial fluoroquinolonyl cephems
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
ATE194353T1 (de) * 1988-10-24 2000-07-15 Norwich Eaton Pharma Antimikrobielle quinolonyllactamester
EP0366193A3 (en) * 1988-10-24 1992-01-08 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial quinolonyl lactams
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
AU640481B2 (en) * 1990-04-18 1993-08-26 Norwich Eaton Pharmaceuticals, Inc. Penicillan or cephalosporin derivatives of quinolonyl

Also Published As

Publication number Publication date
NO941108L (no) 1994-05-31
HU9400940D0 (en) 1994-06-28
KR100253825B1 (ko) 2000-05-01
WO1993007154A1 (en) 1993-04-15
ATE150463T1 (de) 1997-04-15
NO304599B1 (no) 1999-01-18
NO941108D0 (no) 1994-03-25
MX9205620A (es) 1993-12-01
HUT67423A (en) 1995-04-28
FI941490A (fi) 1994-05-02
CN1046523C (zh) 1999-11-17
FI941490A0 (fi) 1994-03-30
CZ73194A3 (en) 1994-11-16
PT100920B (pt) 1999-07-30
DE69218445T2 (de) 1997-08-07
BR9206590A (pt) 1995-04-25
EP0606336A1 (en) 1994-07-20
US5281703A (en) 1994-01-25
EP0606336B1 (en) 1997-03-19
SK37594A3 (en) 1995-02-08
CA2120493A1 (en) 1993-04-15
DE69218445D1 (de) 1997-04-24
RU2130938C1 (ru) 1999-05-27
CN1075146A (zh) 1993-08-11
AU2693892A (en) 1993-05-03
PT100920A (pt) 1993-10-29
NZ244557A (en) 1996-02-27
ES2101119T3 (es) 1997-07-01
DK0606336T3 (da) 1997-04-14
AU667837B2 (en) 1996-04-18

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