GR3020934T3 - Alpha-mannosidase and fucosidase inhibitors - Google Patents

Alpha-mannosidase and fucosidase inhibitors

Info

Publication number
GR3020934T3
GR3020934T3 GR960402291T GR960402291T GR3020934T3 GR 3020934 T3 GR3020934 T3 GR 3020934T3 GR 960402291 T GR960402291 T GR 960402291T GR 960402291 T GR960402291 T GR 960402291T GR 3020934 T3 GR3020934 T3 GR 3020934T3
Authority
GR
Greece
Prior art keywords
alpha
mannosidase
fucosidase inhibitors
beta
fucosidase
Prior art date
Application number
GR960402291T
Other languages
Greek (el)
English (en)
Inventor
Robert A Farr
Norton P Peet
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of GR3020934T3 publication Critical patent/GR3020934T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
GR960402291T 1990-04-12 1996-09-03 Alpha-mannosidase and fucosidase inhibitors GR3020934T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50887590A 1990-04-12 1990-04-12

Publications (1)

Publication Number Publication Date
GR3020934T3 true GR3020934T3 (en) 1996-12-31

Family

ID=24024437

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960402291T GR3020934T3 (en) 1990-04-12 1996-09-03 Alpha-mannosidase and fucosidase inhibitors

Country Status (19)

Country Link
EP (1) EP0451834B1 (enrdf_load_stackoverflow)
JP (1) JP2955057B2 (enrdf_load_stackoverflow)
KR (1) KR100197382B1 (enrdf_load_stackoverflow)
CN (1) CN1033638C (enrdf_load_stackoverflow)
AT (1) ATE140692T1 (enrdf_load_stackoverflow)
AU (1) AU646855B2 (enrdf_load_stackoverflow)
CA (1) CA2040058C (enrdf_load_stackoverflow)
DE (1) DE69121000T2 (enrdf_load_stackoverflow)
DK (1) DK0451834T3 (enrdf_load_stackoverflow)
ES (1) ES2092520T3 (enrdf_load_stackoverflow)
FI (1) FI109200B (enrdf_load_stackoverflow)
GR (1) GR3020934T3 (enrdf_load_stackoverflow)
HU (1) HU213396B (enrdf_load_stackoverflow)
IE (1) IE75195B1 (enrdf_load_stackoverflow)
IL (1) IL97814A (enrdf_load_stackoverflow)
NO (1) NO175856C (enrdf_load_stackoverflow)
NZ (1) NZ237734A (enrdf_load_stackoverflow)
PT (1) PT97339B (enrdf_load_stackoverflow)
ZA (1) ZA912588B (enrdf_load_stackoverflow)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773239A (en) * 1993-10-19 1998-06-30 Mount Sinai Hospital Corporation. Mannosidase inhibitors, process for their preparation and their use as therapeutic agents
US5650413A (en) * 1995-06-07 1997-07-22 Glycodesign Inc. Derivatives of swainsonine, processes for their preparation and their use as therapeutic agents
CN1251588A (zh) * 1996-10-01 2000-04-26 格里科设计公司 新的苦马豆素的3,5和/或6取代的类似物、制备其的方法及作为治疗剂的应用
CA2286766A1 (en) 1997-04-15 1998-10-22 Glycodesign Inc. Alkaloid halide salts of swainsonine and methods of use
JP2001521036A (ja) * 1997-10-24 2001-11-06 グリコデザイン インコーポレイテッド スワインソニン塩の合成
CN102905716B (zh) * 2010-01-28 2016-06-01 雷普特制药公司 以受体相关蛋白(rap)肽-岩藻糖苷酶抑制剂偶联物治疗肝病症的方法
CN101870992A (zh) * 2010-06-21 2010-10-27 天津科技大学 利用基因工程菌耦合发酵合成gdp-岩藻糖的方法
CN102286608B (zh) * 2011-06-08 2014-06-25 郑州安图生物工程股份有限公司 衣原体诊断方法和试剂盒

Also Published As

Publication number Publication date
JP2955057B2 (ja) 1999-10-04
NO175856B (enrdf_load_stackoverflow) 1994-09-12
EP0451834A3 (en) 1993-10-20
NZ237734A (en) 1993-05-26
AU7416491A (en) 1991-10-17
ES2092520T3 (es) 1996-12-01
HU213396B (en) 1997-06-30
CN1055732A (zh) 1991-10-30
NO911419L (no) 1991-10-14
CA2040058C (en) 2001-10-23
IL97814A0 (en) 1992-06-21
DE69121000D1 (de) 1996-08-29
AU646855B2 (en) 1994-03-10
CA2040058A1 (en) 1991-10-13
FI109200B (fi) 2002-06-14
HU911196D0 (en) 1991-10-28
KR100197382B1 (ko) 1999-06-15
ATE140692T1 (de) 1996-08-15
FI911751L (fi) 1991-10-13
DE69121000T2 (de) 1996-12-19
CN1033638C (zh) 1996-12-25
KR910018341A (ko) 1991-11-30
NO911419D0 (no) 1991-04-11
NO175856C (no) 1994-12-21
PT97339A (pt) 1992-01-31
IE911229A1 (en) 1991-10-23
JPH04234834A (ja) 1992-08-24
IL97814A (en) 1995-08-31
PT97339B (pt) 1998-08-31
FI911751A0 (fi) 1991-04-11
DK0451834T3 (da) 1996-08-26
EP0451834B1 (en) 1996-07-24
HUT60994A (en) 1992-11-30
ZA912588B (en) 1992-01-29
EP0451834A2 (en) 1991-10-16
IE75195B1 (en) 1997-08-27

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