GR3020853T3 - Macrocyclic lactam prokinetic agents - Google Patents

Macrocyclic lactam prokinetic agents

Info

Publication number
GR3020853T3
GR3020853T3 GR960402210T GR960402210T GR3020853T3 GR 3020853 T3 GR3020853 T3 GR 3020853T3 GR 960402210 T GR960402210 T GR 960402210T GR 960402210 T GR960402210 T GR 960402210T GR 3020853 T3 GR3020853 T3 GR 3020853T3
Authority
GR
Greece
Prior art keywords
image
pct
prokinetic agents
sec
macrocyclic lactam
Prior art date
Application number
GR960402210T
Other languages
Greek (el)
English (en)
Inventor
Leslie A Freiberg
Carla Edwards
Richard J Pariza
Hugh N Nellans
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of GR3020853T3 publication Critical patent/GR3020853T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Polyamides (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR960402210T 1991-04-09 1996-08-22 Macrocyclic lactam prokinetic agents GR3020853T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68283691A 1991-04-09 1991-04-09
PCT/US1992/002590 WO1992018134A1 (en) 1991-04-09 1992-03-30 Macrocyclic lactam prokinetic agents

Publications (1)

Publication Number Publication Date
GR3020853T3 true GR3020853T3 (en) 1996-11-30

Family

ID=24741372

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960402210T GR3020853T3 (en) 1991-04-09 1996-08-22 Macrocyclic lactam prokinetic agents

Country Status (15)

Country Link
US (1) US5538961A (https=)
EP (1) EP0579770B1 (https=)
JP (1) JPH06509326A (https=)
KR (1) KR100222014B1 (https=)
AT (1) ATE139697T1 (https=)
AU (1) AU663089B2 (https=)
CA (1) CA2103913A1 (https=)
DE (1) DE69211845T2 (https=)
DK (1) DK0579770T3 (https=)
ES (1) ES2091471T3 (https=)
GR (1) GR3020853T3 (https=)
IE (1) IE73236B1 (https=)
IL (1) IL101504A (https=)
PT (1) PT100357B (https=)
WO (1) WO1992018134A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122261A3 (en) * 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
WO2001060833A2 (en) 2000-02-18 2001-08-23 Kosan Biosciences, Inc. Motilide compounds
ATE321770T1 (de) * 2000-08-17 2006-04-15 Kitasato Inst Pseudoerythromycin-derivate
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
CA2429709A1 (en) * 2000-12-01 2002-07-04 Gary Ashley Motilide compounds
SI1532131T1 (sl) * 2002-08-29 2009-04-30 Pfizer Motilidne spojine
AU2003273318A1 (en) * 2002-09-12 2004-04-30 University Of Chicago Monitoring and diagnosis of gastric emptying and gastroparesis
DK1633774T3 (da) 2003-06-18 2010-05-25 Tranzyme Pharma Inc Makrocykliske motilinreceptorantagonister
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
JP2009518396A (ja) * 2005-12-08 2009-05-07 ファイザー・インク エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
EP2431380A3 (en) 2006-09-11 2013-07-03 Tranzyme Pharma, Inc. Macrocyclic antagonist of the motilin receptor for treatment of gastrointestinal dysmotility disorders
CA2670482C (en) * 2006-12-05 2011-10-11 Pfizer Inc. Motilide polymorphs
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
RU2612902C2 (ru) * 2011-07-29 2017-03-13 Кембридж Эпидженетикс Лимитед Способы обнаружения модификации нуклеотидов
CN104955960A (zh) 2012-11-30 2015-09-30 剑桥表现遗传学有限公司 用于修饰的核苷酸的氧化剂
CN115057794B (zh) * 2022-07-07 2023-11-17 桂林理工大学 一种可见光诱导铈催化氧化酰胺去甲基化的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
US5008249A (en) * 1985-08-31 1991-04-16 Kitasato Kenkyusho Therapeutic method of stimulating digestive tract contractile motion in mammals
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
US5202434A (en) * 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers

Also Published As

Publication number Publication date
JPH06509326A (ja) 1994-10-20
ATE139697T1 (de) 1996-07-15
ES2091471T3 (es) 1996-11-01
PT100357A (pt) 1993-07-30
US5538961A (en) 1996-07-23
EP0579770B1 (en) 1996-06-26
IL101504A0 (en) 1992-12-30
AU663089B2 (en) 1995-09-28
CA2103913A1 (en) 1992-10-10
EP0579770A1 (en) 1994-01-26
DK0579770T3 (da) 1996-11-04
IE73236B1 (en) 1997-05-21
PT100357B (pt) 1999-06-30
KR100222014B1 (ko) 1999-10-01
IL101504A (en) 1998-04-05
IE921045A1 (en) 1992-10-21
EP0579770A4 (https=) 1994-03-30
DE69211845D1 (de) 1996-08-01
AU1910392A (en) 1992-11-17
DE69211845T2 (de) 1997-01-23
WO1992018134A1 (en) 1992-10-29

Similar Documents

Publication Publication Date Title
IL101504A0 (en) Macrocyclic lactam prokinetic agents
HUT66660A (en) Intermediates for producing 9-[(substituted glicyl)-amido]-6-demetyl-6-deoxy-tetracyclines and pharmaceutical compositions containing them
IL108520A0 (en) Imidazopyridine derivatives, processes for the preparation thereof, and pharmaceutical compositions containing them
IL99775A0 (en) Antimicrobial agents containing substituted 2-cyclohexan-1-yl-amino derivatives,certain such novel compounds and their preparation
IL101819A0 (en) Amidinophenylalanine derivatives,a process for the preparation thereof,use thereof and agents containing these as anticoagulants
GB9416005D0 (en) Peptidic compounds analogous to distamycin a and process for their preparation
GR3029406T3 (en) Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them.
IL101583A (en) Quinoxalines processes for their preparation and pharmaceutical compositions containing them
HU9401584D0 (en) Preparation of substituted piperidines
EP0450420A3 (en) Dihydropyridines substituted by heterocycles, process for their preparation and their use in medicaments
ZA93494B (en) Napthalene amides and sulphonamides, processes for their preparation and pharmaceutical compositions containing them
ZA932359B (en) 3-Aminochroman spiro compounds processes for preparing them and pharmaceutical compositions containing them
EP0457090A3 (en) Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives
IL99898A0 (en) 7-acyl-3-substituted carbamoyloxy cephem compounds,their preparation and antibacterial compositions containing them
GR3023757T3 (en) Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents.
ZA942964B (en) Pyrrolopyrazine compounds processes for their preparation and the pharmaceutical compositions which contain them
CY2160B1 (en) Erburnane derivatives processes for their preparation and pharmaceutical compositions containing them
HK27096A (en) Benzofuranylimidazole derivatives
TW232011B (https=)
EP0418990A3 (en) 13-bromo and 13,14-dibromo ergoline, their preparation and their use
GR3015706T3 (en) Benzylselenobenzamides of aminopyridines and picolylamines.
IL99369A0 (en) Pharmaceutical compositions containing substituted 2-cyclohexene derivatives
MY110894A (en) New pyrazolylpryrazoles, processes for their preparation, as well as intermediates, and thier use as herbicides