GR3029406T3 - Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them. - Google Patents

Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them.

Info

Publication number
GR3029406T3
GR3029406T3 GR990400488T GR990400488T GR3029406T3 GR 3029406 T3 GR3029406 T3 GR 3029406T3 GR 990400488 T GR990400488 T GR 990400488T GR 990400488 T GR990400488 T GR 990400488T GR 3029406 T3 GR3029406 T3 GR 3029406T3
Authority
GR
Greece
Prior art keywords
pyridothiadiazines
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
GR990400488T
Other languages
Greek (el)
Inventor
Bernard Pirotte
Tullio Pascal De
Bernard Masereel
Jacques Delarge
Jean Lepagnol
Pierre Renard
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of GR3029406T3 publication Critical patent/GR3029406T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The invention relates to the compounds of formula (I): <IMAGE> in which A, R1, R2 and R4 are as defined in the description. Medicaments.
GR990400488T 1993-03-26 1999-02-16 Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them. GR3029406T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9303458A FR2703051B1 (en) 1993-03-26 1993-03-26 New pyridothiadiazines, processes for their preparation, and pharmaceutical compositions containing them.

Publications (1)

Publication Number Publication Date
GR3029406T3 true GR3029406T3 (en) 1999-05-28

Family

ID=9445338

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990400488T GR3029406T3 (en) 1993-03-26 1999-02-16 Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them.

Country Status (13)

Country Link
US (1) US5459138A (en)
EP (1) EP0618209B1 (en)
JP (1) JP2513989B2 (en)
AT (1) ATE174920T1 (en)
AU (1) AU673893B2 (en)
CA (1) CA2119853C (en)
DE (1) DE69415373T2 (en)
DK (1) DK0618209T3 (en)
ES (1) ES2128519T3 (en)
FR (1) FR2703051B1 (en)
GR (1) GR3029406T3 (en)
NZ (1) NZ260186A (en)
ZA (1) ZA942131B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5488056A (en) * 1994-10-31 1996-01-30 Eli Lilly And Company Method for treating anxiety
US6133258A (en) * 1995-11-05 2000-10-17 Yamanouchi Pharmaceutical Co., Ltd. Inhibitor of kainic acid neurotoxicity and pyridothiazine derivative
US6225310B1 (en) 1996-01-17 2001-05-01 Novo Nordisk A/S Fused 1,2,4-thiadiazine derivatives, their preparation and use
IL125072A (en) * 1996-01-17 2002-12-01 Novo Nordisk As Pyrido-1,2,4- thiadiazin-3-amine derivatives and pharmaceutical compositions containing them
PL327938A1 (en) * 1996-01-17 1999-01-04 Novo Nordisk As Derivatives of 1,2,4-thiadiazine and 1,4-thiazine, their production and application
EP0918518A4 (en) * 1996-04-19 2002-05-02 Univ California Treatment of mood/affective disorders by glutamatergic upmodulators
CZ297521B6 (en) * 1996-09-24 2007-01-03 Dow Agrosciences Llc N-([2,2,4]triazoloazinyl)benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicidal agents
US6329368B1 (en) * 1997-05-09 2001-12-11 The Regents Of The University Of California Endocrine modulation with positive modulators of AMPA type glutamate receptors
HUP0003999A3 (en) * 1997-07-16 2003-03-28 Novo Nordisk As Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them
WO1999032495A1 (en) * 1997-12-19 1999-07-01 Novo Nordisk A/S Pyrido 1,2,4-thiadiazine derivatives, their preparation and use
DE19824232A1 (en) * 1998-05-29 1999-12-02 Bayer Ag Pyridodithiazine dioxides
DE19918021C1 (en) 1999-04-21 2000-06-29 Ruetgers Organics Gmbh Preparation of chlorinated pyridine sulfonic acid chloride derivatives from hydroxypyridine sulfonic acids and phosphorus trichloride/chlorine gas; useful as intermediates for drugs, e.g. torasemide
EP1194430A1 (en) * 1999-06-30 2002-04-10 Novo Nordisk A/S Novel process
CA2403382A1 (en) 2000-03-20 2001-09-27 Teva Pharmaceutical Industries Ltd. Novel processes for preparing torsemide intermediate
AU2001265841A1 (en) * 2000-06-26 2002-01-08 Novo-Nordisk A/S Use of potassium channel openers for the treatment of insulitis
AU2002307327A1 (en) * 2001-05-04 2002-11-18 Eli Lilly And Company Use of an ampa receptor potentiator for the manufacture of a medicament for the treatment of type 2 diabetes
US7902203B2 (en) 2002-11-01 2011-03-08 Abbott Laboratories, Inc. Anti-infective agents
US7378414B2 (en) 2003-08-25 2008-05-27 Abbott Laboratories Anti-infective agents
US7492956B2 (en) * 2004-08-18 2009-02-17 Cisco Technology, Inc. Video coding using multi-dimensional amplitude coding and 2-D non-zero/zero cluster position coding
EP1781265B1 (en) 2004-08-25 2010-04-07 Essentialis, Inc. Pharmaceutical formulations of potassium atp channel openers and uses thereof
WO2006093801A1 (en) * 2005-02-25 2006-09-08 Abbott Laboratories Thiadiazine derivatives useful as anti-infective agents
EP1777219A1 (en) * 2005-10-20 2007-04-25 Faust Pharmaceuticals 1,2-Substituted naphthalene derivatives with antiglutamatergic properties and uses thereof
WO2007081521A2 (en) 2006-01-05 2007-07-19 Essentialis, Inc. Salts of potassium atp channel openers and uses thereof
CN100393726C (en) * 2006-04-20 2008-06-11 山东大学 Process for preparing 2,4-disubstituted heterocyclo [4,5-e][1,2,4] thiadiazine derivatives
CN110054647B (en) * 2019-05-23 2021-06-15 上海勋和医药科技有限公司 Torasemide phosphate prodrugs, preparation method and composition thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157647A (en) * 1960-10-31 1964-11-17 Olin Mathieson Process for producing nu-alkyl and nu-aralkyl thiadiazine compounds
US3288678A (en) * 1963-09-12 1966-11-29 Ciba Geigy Corp Diuretic compositions
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
JPS5854158B2 (en) * 1975-10-02 1983-12-02 ヒサミツセイヤク カブシキガイシヤ Synquinapyridothiadiagin

Also Published As

Publication number Publication date
DK0618209T3 (en) 1999-08-23
EP0618209B1 (en) 1998-12-23
DE69415373D1 (en) 1999-02-04
FR2703051B1 (en) 1995-04-28
NZ260186A (en) 1995-07-26
ATE174920T1 (en) 1999-01-15
ZA942131B (en) 1995-04-05
ES2128519T3 (en) 1999-05-16
JP2513989B2 (en) 1996-07-10
DE69415373T2 (en) 1999-08-26
FR2703051A1 (en) 1994-09-30
US5459138A (en) 1995-10-17
CA2119853A1 (en) 1994-09-27
AU673893B2 (en) 1996-11-28
JPH072872A (en) 1995-01-06
EP0618209A1 (en) 1994-10-05
CA2119853C (en) 2002-09-10
AU5904894A (en) 1994-09-29

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