GR3020848T3 - 1,8-Naphthyridin-2-one derivatives - Google Patents

1,8-Naphthyridin-2-one derivatives

Info

Publication number
GR3020848T3
GR3020848T3 GR960402205T GR960402205T GR3020848T3 GR 3020848 T3 GR3020848 T3 GR 3020848T3 GR 960402205 T GR960402205 T GR 960402205T GR 960402205 T GR960402205 T GR 960402205T GR 3020848 T3 GR3020848 T3 GR 3020848T3
Authority
GR
Greece
Prior art keywords
substituted
lower alkyl
chem
single bond
unsubstituted
Prior art date
Application number
GR960402205T
Other languages
English (en)
Inventor
Fumio Suzuki
Takeshi Kuroda
Kenji Ohmori
Tadafumi Tamura
Hisashi Hosoe
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of GR3020848T3 publication Critical patent/GR3020848T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GR960402205T 1990-04-16 1996-08-22 1,8-Naphthyridin-2-one derivatives GR3020848T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10000690 1990-04-16

Publications (1)

Publication Number Publication Date
GR3020848T3 true GR3020848T3 (en) 1996-11-30

Family

ID=14262483

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960402205T GR3020848T3 (en) 1990-04-16 1996-08-22 1,8-Naphthyridin-2-one derivatives

Country Status (9)

Country Link
US (1) US5126341A (el)
EP (1) EP0452873B1 (el)
JP (1) JP2988739B2 (el)
AT (1) ATE140003T1 (el)
CA (1) CA2040517C (el)
DE (1) DE69120581T2 (el)
DK (1) DK0452873T3 (el)
ES (1) ES2093041T3 (el)
GR (1) GR3020848T3 (el)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
GB9127252D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
GB9312891D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
GB9318931D0 (en) * 1993-09-14 1993-10-27 Boots Co Plc Therapeutic agents
GB9409264D0 (en) * 1994-05-10 1994-06-29 Boots Co Ltd Therapeutic agents
GB9420172D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
GB9420168D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
KR20090090406A (ko) * 2000-12-18 2009-08-25 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 염증성 사이토카인 생산 유리 억제제
DE10222895A1 (de) * 2002-05-23 2003-12-11 Bosch Gmbh Robert Hochdruckspeicher für Kraftstoffeinspritzsysteme mit integriertem Druckregelventil
CA2487900A1 (en) * 2002-06-05 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Immunity-related protein kinase inhibitors
CA2487891A1 (en) * 2002-06-05 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Inhibitors against the activation of ap-1 and nfat
EA008769B1 (ru) * 2002-06-05 2007-08-31 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Лекарственное средство для лечения диабета
EA009051B1 (ru) 2002-06-06 2007-10-26 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. О-замещенные гидроксиарильные производные
EP1514544A4 (en) * 2002-06-06 2009-01-07 Inst Med Molecular Design Inc HYPO-ALLERGENIC
CA2489091A1 (en) * 2002-06-10 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Inhibitors against activation of nf-kappab
AU2003242108B2 (en) * 2002-06-10 2008-09-11 Institute Of Medicinal Molecular Design, Inc. Medicament for treatment of cancer
CN100490793C (zh) * 2002-06-11 2009-05-27 株式会社医药分子设计研究所 神经变性疾病治疗药
KR20050074949A (ko) * 2002-11-12 2005-07-19 엔오케이 가부시키가이샤 고무형상 탄성부품
ES2393326T3 (es) * 2006-12-18 2012-12-20 Amgen, Inc Compuestos basados en azaquinolona que presentan actividad inhibidora de prolil hidroxilasas, composiciones y usos de los mismos
EP2111399A2 (en) * 2006-12-18 2009-10-28 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
CA2683956C (en) * 2007-04-18 2012-12-18 Amgen Inc. Quinolones and azaquinolones that inhibit prolyl hydroxylase
US7569726B2 (en) * 2007-04-18 2009-08-04 Amgen Inc. Indanone derivatives that inhibit prolyl hydroxylase
CA2685219C (en) * 2007-05-04 2012-06-19 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
ES2389063T3 (es) * 2007-05-04 2012-10-22 Amgen, Inc Derivados de tienopiridina y tiazolopiridina que inhiben la actividad prolil hidroxilasa
EP2855479B1 (en) 2012-04-05 2016-03-30 Boehringer Ingelheim International GmbH 1,8-naphthyridin-2(1h)-one derivatives as cytomegalovirus inhibitors
BR112022022335A2 (pt) 2020-05-05 2023-01-10 Teon Therapeutics Inc Moduladores de receptor canabinoide tipo 2 (cb2) e usos dos mesmos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US4264602A (en) * 1975-08-15 1981-04-28 Sandoz, Inc. 4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
DE2635216A1 (de) * 1975-08-15 1977-03-03 Sandoz Ag 4-hydorxy-3-nitropyrido eckige klammer auf 2,3-b eckige klammer zu pyridin2-one und ihre herstellung
US4128649A (en) * 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
US4215123A (en) * 1979-05-07 1980-07-29 American Home Products Corporation Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives
DE3368929D1 (de) * 1982-04-26 1987-02-12 Schering Corp 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
CA1305478C (en) * 1986-11-06 1992-07-21 Margaret H. Sherlock Naphthyridine and pyridopyrazine compounds and pharmaceutical usage thereof

Also Published As

Publication number Publication date
JP2988739B2 (ja) 1999-12-13
EP0452873A1 (en) 1991-10-23
CA2040517C (en) 1997-06-03
ES2093041T3 (es) 1996-12-16
CA2040517A1 (en) 1991-10-17
ATE140003T1 (de) 1996-07-15
US5126341A (en) 1992-06-30
JPH04217981A (ja) 1992-08-07
DE69120581D1 (de) 1996-08-08
DE69120581T2 (de) 1996-10-31
EP0452873B1 (en) 1996-07-03
DK0452873T3 (da) 1996-07-29

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