DK0452873T3 - 1,8-naphthyridin-2-on-derivater - Google Patents

1,8-naphthyridin-2-on-derivater

Info

Publication number
DK0452873T3
DK0452873T3 DK91106040.8T DK91106040T DK0452873T3 DK 0452873 T3 DK0452873 T3 DK 0452873T3 DK 91106040 T DK91106040 T DK 91106040T DK 0452873 T3 DK0452873 T3 DK 0452873T3
Authority
DK
Denmark
Prior art keywords
substituted
lower alkyl
chem
single bond
unsubstituted
Prior art date
Application number
DK91106040.8T
Other languages
English (en)
Inventor
Takeshi Kuroda
Fumio Suzuki
Kenji Ohmori
Tadafumi Tamura
Hisashi Hosoe
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of DK0452873T3 publication Critical patent/DK0452873T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK91106040.8T 1990-04-16 1991-04-16 1,8-naphthyridin-2-on-derivater DK0452873T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10000690 1990-04-16

Publications (1)

Publication Number Publication Date
DK0452873T3 true DK0452873T3 (da) 1996-07-29

Family

ID=14262483

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91106040.8T DK0452873T3 (da) 1990-04-16 1991-04-16 1,8-naphthyridin-2-on-derivater

Country Status (9)

Country Link
US (1) US5126341A (da)
EP (1) EP0452873B1 (da)
JP (1) JP2988739B2 (da)
AT (1) ATE140003T1 (da)
CA (1) CA2040517C (da)
DE (1) DE69120581T2 (da)
DK (1) DK0452873T3 (da)
ES (1) ES2093041T3 (da)
GR (1) GR3020848T3 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
GB9127252D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
GB9312891D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
GB9318931D0 (en) * 1993-09-14 1993-10-27 Boots Co Plc Therapeutic agents
GB9409264D0 (en) * 1994-05-10 1994-06-29 Boots Co Ltd Therapeutic agents
GB9420168D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
GB9420172D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
US8263657B2 (en) * 2000-12-18 2012-09-11 Institute Of Medicinal Molecular Design, Inc. Inhibitors against the production and release of inflammatory cytokines
DE10222895A1 (de) * 2002-05-23 2003-12-11 Bosch Gmbh Robert Hochdruckspeicher für Kraftstoffeinspritzsysteme mit integriertem Druckregelventil
CA2487891A1 (en) * 2002-06-05 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Inhibitors against the activation of ap-1 and nfat
WO2003103658A1 (ja) * 2002-06-05 2003-12-18 株式会社医薬分子設計研究所 免疫関連プロテインキナーゼ阻害剤
CN100379410C (zh) * 2002-06-05 2008-04-09 株式会社医药分子设计研究所 糖尿病治疗药
US7626042B2 (en) 2002-06-06 2009-12-01 Institute Of Medicinal Molecular Design, Inc. O-substituted hydroxyaryl derivatives
CA2488367A1 (en) * 2002-06-06 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Antiallergic agents
EP1535610A4 (en) * 2002-06-10 2008-12-31 Inst Med Molecular Design Inc THERAPEUTIC CANCER
CN100464742C (zh) * 2002-06-10 2009-03-04 株式会社医药分子设计研究所 NF-κB活化抑制剂
TWI280127B (en) * 2002-06-11 2007-05-01 Inst Med Molecular Design Inc Remedies for neurodegenerative diseases
CN100417847C (zh) * 2002-11-12 2008-09-10 Nok株式会社 橡胶状弹性部件
WO2008076425A1 (en) * 2006-12-18 2008-06-26 Amgen Inc. Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
CA2672656C (en) * 2006-12-18 2012-03-20 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
EP2155680B1 (en) * 2007-04-18 2013-12-04 Amgen, Inc Indanone derivatives that inhibit prolyl hydroxylase
US8048894B2 (en) * 2007-04-18 2011-11-01 Amgen Inc. Quinolones and azaquinolones that inhibit prolyl hydroxylase
US8097620B2 (en) * 2007-05-04 2012-01-17 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
US8030346B2 (en) * 2007-05-04 2011-10-04 Amgen Inc. Heterocyclic quinolone derivatives that inhibit prolyl hydroxylase activity
US9249158B2 (en) 2012-04-05 2016-02-02 Boehringer Ingelheim International Gmbh Cytomegalovirus inhibitor compounds
KR20230041654A (ko) * 2020-05-05 2023-03-24 테온 테라퓨틱스, 인크. 칸나비노이드 수용체 유형 2 (cb2) 조정제 및 그의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
DE2635216A1 (de) * 1975-08-15 1977-03-03 Sandoz Ag 4-hydorxy-3-nitropyrido eckige klammer auf 2,3-b eckige klammer zu pyridin2-one und ihre herstellung
US4264602A (en) * 1975-08-15 1981-04-28 Sandoz, Inc. 4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
US4128649A (en) * 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
US4215123A (en) * 1979-05-07 1980-07-29 American Home Products Corporation Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives
DE3368929D1 (de) * 1982-04-26 1987-02-12 Schering Corp 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
CA1305478C (en) * 1986-11-06 1992-07-21 Margaret H. Sherlock Naphthyridine and pyridopyrazine compounds and pharmaceutical usage thereof

Also Published As

Publication number Publication date
US5126341A (en) 1992-06-30
JPH04217981A (ja) 1992-08-07
ATE140003T1 (de) 1996-07-15
EP0452873A1 (en) 1991-10-23
CA2040517A1 (en) 1991-10-17
JP2988739B2 (ja) 1999-12-13
DE69120581D1 (de) 1996-08-08
EP0452873B1 (en) 1996-07-03
DE69120581T2 (de) 1996-10-31
CA2040517C (en) 1997-06-03
GR3020848T3 (en) 1996-11-30
ES2093041T3 (es) 1996-12-16

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