GR3018321T3 - N-hydroxyurea derivatives which inhibit lipoxygenase. - Google Patents

N-hydroxyurea derivatives which inhibit lipoxygenase.

Info

Publication number
GR3018321T3
GR3018321T3 GR950403281T GR950403281T GR3018321T3 GR 3018321 T3 GR3018321 T3 GR 3018321T3 GR 950403281 T GR950403281 T GR 950403281T GR 950403281 T GR950403281 T GR 950403281T GR 3018321 T3 GR3018321 T3 GR 3018321T3
Authority
GR
Greece
Prior art keywords
alkyl
carbon atoms
lipoxygenase
alkoxy
treating
Prior art date
Application number
GR950403281T
Other languages
English (en)
Inventor
Kazuo Ando
Takafumi Ikeda
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3018321T3 publication Critical patent/GR3018321T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Lubricants (AREA)
  • Cleaning Or Clearing Of The Surface Of Open Water (AREA)
GR950403281T 1991-06-13 1995-12-07 N-hydroxyurea derivatives which inhibit lipoxygenase. GR3018321T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3142123A JPH07100687B2 (ja) 1991-06-13 1991-06-13 新規なｎ−ヒドロキシ尿素化合物および組成物
PCT/US1992/004007 WO1992022543A1 (en) 1991-06-13 1992-05-21 N-hydroxyurea derivatives which inhibit lipoxygenase

Publications (1)

Publication Number Publication Date
GR3018321T3 true GR3018321T3 (en) 1996-03-31

Family

ID=15307927

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950403281T GR3018321T3 (en) 1991-06-13 1995-12-07 N-hydroxyurea derivatives which inhibit lipoxygenase.

Country Status (13)

Country Link
US (1) US5384320A (el)
EP (1) EP0588850B1 (el)
JP (1) JPH07100687B2 (el)
AT (1) ATE131162T1 (el)
CA (1) CA2109800C (el)
DE (1) DE69206616T2 (el)
DK (1) DK0588850T3 (el)
ES (1) ES2081111T3 (el)
FI (1) FI935552A0 (el)
GR (1) GR3018321T3 (el)
IE (1) IE69369B1 (el)
PT (1) PT100582A (el)
WO (1) WO1992022543A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3179286B2 (ja) * 1994-05-19 2001-06-25 ファイザー製薬株式会社 Ｎ−ヒドロキシ尿素系抗炎症剤
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3686733T2 (de) * 1985-03-16 1993-02-11 Wellcome Found Aryl-derivate.
ES2053609T3 (es) * 1987-04-24 1994-08-01 Abbott Lab Derivados de urea inhibidores de lipoxigenasa.
US5068251A (en) * 1988-12-16 1991-11-26 Abbott Laboratories Lipoxygenase inhibiting compounds
US4981865A (en) * 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents

Also Published As

Publication number Publication date
ES2081111T3 (es) 1996-02-16
JPH04368366A (ja) 1992-12-21
IE69369B1 (en) 1996-09-04
US5384320A (en) 1995-01-24
CA2109800A1 (en) 1992-12-23
DK0588850T3 (da) 1996-01-08
DE69206616D1 (de) 1996-01-18
FI935552A (fi) 1993-12-10
PT100582A (pt) 1993-08-31
IE921902A1 (en) 1992-12-16
FI935552A0 (fi) 1993-12-10
EP0588850B1 (en) 1995-12-06
ATE131162T1 (de) 1995-12-15
JPH07100687B2 (ja) 1995-11-01
CA2109800C (en) 1996-03-19
EP0588850A1 (en) 1994-03-30
DE69206616T2 (de) 1996-04-25
WO1992022543A1 (en) 1992-12-23

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