DE69207597D1 - Lipoxygenase inhibierende tetrahydrobenzazepinderivate - Google Patents

Lipoxygenase inhibierende tetrahydrobenzazepinderivate

Info

Publication number
DE69207597D1
DE69207597D1 DE69207597T DE69207597T DE69207597D1 DE 69207597 D1 DE69207597 D1 DE 69207597D1 DE 69207597 T DE69207597 T DE 69207597T DE 69207597 T DE69207597 T DE 69207597T DE 69207597 D1 DE69207597 D1 DE 69207597D1
Authority
DE
Germany
Prior art keywords
alkyl
pct
lipoxygenase
sec
arylalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69207597T
Other languages
English (en)
Other versions
DE69207597T2 (de
Inventor
Takafumi Ikeda
Yoko Hoshino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69207597D1 publication Critical patent/DE69207597D1/de
Publication of DE69207597T2 publication Critical patent/DE69207597T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
DE69207597T 1991-06-28 1992-05-27 Lipoxygenase inhibierende tetrahydrobenzazepinderivate Expired - Fee Related DE69207597T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3158832A JPH0717612B2 (ja) 1991-06-28 1991-06-28 新規なテトラヒドロベンズアゼピン誘導体
PCT/US1992/004197 WO1993000335A1 (en) 1991-06-28 1992-05-27 Tetrahydrobenzazepine derivatives which inhibit lipoxygenase

Publications (2)

Publication Number Publication Date
DE69207597D1 true DE69207597D1 (de) 1996-02-22
DE69207597T2 DE69207597T2 (de) 1996-05-23

Family

ID=15680372

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69207597T Expired - Fee Related DE69207597T2 (de) 1991-06-28 1992-05-27 Lipoxygenase inhibierende tetrahydrobenzazepinderivate

Country Status (13)

Country Link
US (1) US5478822A (de)
EP (1) EP0591255B1 (de)
JP (1) JPH0717612B2 (de)
AT (1) ATE132857T1 (de)
CA (1) CA2111460C (de)
DE (1) DE69207597T2 (de)
DK (1) DK0591255T3 (de)
ES (1) ES2082474T3 (de)
FI (1) FI935867A0 (de)
GR (1) GR3019196T3 (de)
IE (1) IE70234B1 (de)
PT (1) PT100628A (de)
WO (1) WO1993000335A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69421183T2 (de) * 1993-07-20 2000-01-20 Pfizer Inc., New York Heteroaryl-cyloalkenyl-hydroxy-harnstoeffe
JP2001501172A (ja) * 1996-08-15 2001-01-30 スミスクライン・ビーチャム・コーポレイション Ｉｌ―８レセプターアンタゴニスト
JP3852117B2 (ja) 1998-02-13 2006-11-29 株式会社安川電機 リニアモータ
EP1283199A4 (de) 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd Antagonisten des melanin-konzentrierenden hormons

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201300B (en) * 1985-03-16 1990-10-28 Wellcome Found Process for production of derivatives of aryl and medical compositions containing them as active substance
EP0279263B1 (de) * 1987-02-10 1993-08-04 Abbott Laboratories Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen
DE3888574T2 (de) * 1987-04-24 1994-06-30 Abbott Lab Harnstoff-Derivate mit lipoxygenasehemmender Wirkung.
US4981865A (en) * 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents

Also Published As

Publication number Publication date
ATE132857T1 (de) 1996-01-15
EP0591255A1 (de) 1994-04-13
CA2111460C (en) 1996-11-19
DE69207597T2 (de) 1996-05-23
CA2111460A1 (en) 1993-01-07
GR3019196T3 (en) 1996-06-30
US5478822A (en) 1995-12-26
JPH0717612B2 (ja) 1995-03-01
IE922075A1 (en) 1992-12-30
JPH059181A (ja) 1993-01-19
WO1993000335A1 (en) 1993-01-07
FI935867A (fi) 1993-12-27
IE70234B1 (en) 1996-11-13
EP0591255B1 (de) 1996-01-10
FI935867A0 (fi) 1993-12-27
PT100628A (pt) 1993-09-30
ES2082474T3 (es) 1996-03-16
DK0591255T3 (da) 1996-02-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee