GR3019196T3 - Tetrahydrobenzazepine derivatives which inhibit lipoxygenase - Google Patents

Tetrahydrobenzazepine derivatives which inhibit lipoxygenase

Info

Publication number
GR3019196T3
GR3019196T3 GR960400599T GR960400599T GR3019196T3 GR 3019196 T3 GR3019196 T3 GR 3019196T3 GR 960400599 T GR960400599 T GR 960400599T GR 960400599 T GR960400599 T GR 960400599T GR 3019196 T3 GR3019196 T3 GR 3019196T3
Authority
GR
Greece
Prior art keywords
alkyl
pct
lipoxygenase
sec
arylalkyl
Prior art date
Application number
GR960400599T
Other languages
English (en)
Inventor
Takafumi Ikeda
Yoko Hoshino
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3019196T3 publication Critical patent/GR3019196T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
GR960400599T 1991-06-28 1996-03-05 Tetrahydrobenzazepine derivatives which inhibit lipoxygenase GR3019196T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3158832A JPH0717612B2 (ja) 1991-06-28 1991-06-28 新規なテトラヒドロベンズアゼピン誘導体
PCT/US1992/004197 WO1993000335A1 (en) 1991-06-28 1992-05-27 Tetrahydrobenzazepine derivatives which inhibit lipoxygenase

Publications (1)

Publication Number Publication Date
GR3019196T3 true GR3019196T3 (en) 1996-06-30

Family

ID=15680372

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960400599T GR3019196T3 (en) 1991-06-28 1996-03-05 Tetrahydrobenzazepine derivatives which inhibit lipoxygenase

Country Status (13)

Country Link
US (1) US5478822A (el)
EP (1) EP0591255B1 (el)
JP (1) JPH0717612B2 (el)
AT (1) ATE132857T1 (el)
CA (1) CA2111460C (el)
DE (1) DE69207597T2 (el)
DK (1) DK0591255T3 (el)
ES (1) ES2082474T3 (el)
FI (1) FI935867A (el)
GR (1) GR3019196T3 (el)
IE (1) IE70234B1 (el)
PT (1) PT100628A (el)
WO (1) WO1993000335A1 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2139746T3 (es) * 1993-07-20 2000-02-16 Pfizer Heteroaril cicloalquenil hidroxiureas.
WO1998006701A1 (en) * 1996-08-15 1998-02-19 Smithkline Beecham Corporation Il-8 receptor antagonists
WO1999041825A1 (fr) 1998-02-13 1999-08-19 Kabushiki Kaisha Yaskawa Denki Moteur lineaire
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0196184B1 (en) * 1985-03-16 1992-09-16 The Wellcome Foundation Limited Aryl derivatives
EP0279263B1 (en) * 1987-02-10 1993-08-04 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
DE3888574T2 (de) * 1987-04-24 1994-06-30 Abbott Lab Harnstoff-Derivate mit lipoxygenasehemmender Wirkung.
US4981865A (en) * 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents

Also Published As

Publication number Publication date
JPH059181A (ja) 1993-01-19
DE69207597T2 (de) 1996-05-23
FI935867A0 (fi) 1993-12-27
CA2111460A1 (en) 1993-01-07
WO1993000335A1 (en) 1993-01-07
EP0591255B1 (en) 1996-01-10
DE69207597D1 (de) 1996-02-22
IE70234B1 (en) 1996-11-13
US5478822A (en) 1995-12-26
EP0591255A1 (en) 1994-04-13
ES2082474T3 (es) 1996-03-16
CA2111460C (en) 1996-11-19
DK0591255T3 (da) 1996-02-12
PT100628A (pt) 1993-09-30
JPH0717612B2 (ja) 1995-03-01
FI935867A (fi) 1993-12-27
IE922075A1 (en) 1992-12-30
ATE132857T1 (de) 1996-01-15

Similar Documents

Publication Publication Date Title
PH30793A (en) Benzamide derivatives and pharmaceutical composition comprising the same.
RU95108387A (ru) Дикетопиперазин, способ его получения, фармацевтическая композиция, применение дикетопиперазина
IL108259A0 (en) Piperazine derivates, their preparation and pharmaceutical compositions containing them
NZ334701A (en) Dihydropyrones and use in treating retrovirus infections and diseases
HUT59124A (en) Process for producing 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxane derivatives and pharmaceutical compositions comprising such derivatives as active ingredient
GR3019196T3 (en) Tetrahydrobenzazepine derivatives which inhibit lipoxygenase
ES2121218T3 (es) Fenoxifenilciclopentenilhidroxiureas.
BG106152A (en) 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives
GR3018321T3 (en) N-hydroxyurea derivatives which inhibit lipoxygenase.
DK0651743T3 (da) Indolinyl-N-hydroxyurinstof- og N-hydroxamsyrederivater som lipoxygenaseinhibitorer
IL115085A (en) Piperazine bicyclic carboxamide derivatives their preparation and pharmaceutical compositions containing them
YU79401A (sh) Derivati 1-trifluorometil-4-hidroksi-7-piperidinil- aminometilhromana