GR3017415T3 - Improved composition, device and method of assaying for peroxidatively active substances. - Google Patents

Improved composition, device and method of assaying for peroxidatively active substances.

Info

Publication number
GR3017415T3
GR3017415T3 GR950402354T GR950402354T GR3017415T3 GR 3017415 T3 GR3017415 T3 GR 3017415T3 GR 950402354 T GR950402354 T GR 950402354T GR 950402354 T GR950402354 T GR 950402354T GR 3017415 T3 GR3017415 T3 GR 3017415T3
Authority
GR
Greece
Prior art keywords
indicator
peroxidatively active
active substance
assay
improved
Prior art date
Application number
GR950402354T
Other languages
English (en)
Inventor
Michael J Pugia
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of GR3017415T3 publication Critical patent/GR3017415T3/el

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521—Single-layer analytical elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/725—Haemoglobin using peroxidative activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/10—Benzidines
    • C12Q2326/12—3,3',5,5'-Tetramethylbenzidine, i.e. TMB
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/904—Oxidation - reduction indicators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
GR950402354T 1990-01-30 1995-09-14 Improved composition, device and method of assaying for peroxidatively active substances. GR3017415T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/472,295 US5318894A (en) 1990-01-30 1990-01-30 Composition, device and method of assaying for peroxidatively active substances

Publications (1)

Publication Number Publication Date
GR3017415T3 true GR3017415T3 (en) 1995-12-31

Family

ID=23874919

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950402354T GR3017415T3 (en) 1990-01-30 1995-09-14 Improved composition, device and method of assaying for peroxidatively active substances.

Country Status (11)

Country Link
US (2) US5318894A (el)
EP (1) EP0444263B1 (el)
JP (1) JP2922003B2 (el)
KR (1) KR0163793B1 (el)
AT (1) ATE127851T1 (el)
AU (1) AU623038B2 (el)
CA (1) CA2025803A1 (el)
DE (1) DE69022393T2 (el)
DK (1) DK0444263T3 (el)
ES (1) ES2078934T3 (el)
GR (1) GR3017415T3 (el)

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AU8334698A (en) 1997-07-15 1999-02-10 Kem-En-Tec A/S Pre-stained 3,3',5,5'-tetramethylbenzidine substrates for the detection of enzyme activity
US6121050A (en) * 1997-08-29 2000-09-19 Han; Chi-Neng Arthur Analyte detection systems
CA2249778A1 (en) * 1997-12-15 1999-06-15 Bayer Corporation Competitive apo-peroxidase assay
ES2143434B1 (es) 1998-09-16 2000-12-16 Cerrato Paula Jimenez Pañal con indicadores sensibles al estado de la orina que lo impregna visualiazables desde el exterior.
US6001656A (en) * 1998-09-28 1999-12-14 Bayer Corporation Method for the detection of creatinine
US6689618B1 (en) 2000-04-03 2004-02-10 Shuenn Tzong Chen Method and test strip of detecting oxidizing adulterant in urine
US6743597B1 (en) * 2000-06-13 2004-06-01 Lifescan, Inc. Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
WO2002090930A2 (en) * 2001-05-09 2002-11-14 Biofx Laboratories, Inc. Stabilizing peroxides with stannous halides
JP4618932B2 (ja) * 2001-05-28 2011-01-26 株式会社同仁化学研究所 塩素濃度の測定用組成物
US7459127B2 (en) * 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
US20030170905A1 (en) * 2002-03-05 2003-09-11 Alexander Kamyshny Diagnostic beads for the detection of blood in animal excreta and a method for production thereof
US7125711B2 (en) * 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7435381B2 (en) * 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
MX2007010449A (es) * 2005-02-28 2007-11-08 Premd Inc Metodo y aparato para la medicion no invasiva de colesterol en tejido cutaneo.
WO2008137213A1 (en) * 2007-05-02 2008-11-13 Siemens Healthcare Diagnostics Inc. Piezo dispensing of a diagnostic liquid onto a reagent surface
JP5422108B2 (ja) 2007-10-16 2014-02-19 栄研化学株式会社 ヘムタンパク質の安定化方法及び保存溶液
CA2623328A1 (en) * 2008-02-28 2009-08-28 Francois Mestrallet Mammalian disease detection system
US20130202499A1 (en) * 2012-01-31 2013-08-08 Kimberly-Clark Worldwide, Inc. Composition and Sensor for Detecting Occult Blood
EP3019559A4 (en) 2013-08-22 2017-04-05 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
WO2015109136A2 (en) 2014-01-16 2015-07-23 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
US9091682B1 (en) 2014-05-01 2015-07-28 Steven M Hacker Tissue specimen bottle with color indicator in lid verifying and confirming presence of human tissue or blood contained in specimen bottle
CN107406353A (zh) 2015-02-26 2017-11-28 索尼公司 苯基乙炔基萘染料和用于它们用途的方法
US11827661B2 (en) 2015-02-26 2023-11-28 Sony Group Corporation Water soluble fluorescent or colored dyes comprising conjugating groups
EP3294811B1 (en) 2015-05-11 2024-02-28 Sony Group Corporation Ultra bright dimeric or polymeric dyes
DE102016203335A1 (de) * 2016-03-01 2017-09-07 Axagarius Gmbh & Co. Kg Test zur Bestimmung einer Basen-Konzentration
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JP7145079B2 (ja) 2016-04-01 2022-09-30 ソニーグループ株式会社 剛性のスペーシング基を有する超明色ダイマーまたはポリマー染料
CA3019951A1 (en) 2016-04-06 2017-10-12 Sony Corporation Ultra bright dimeric or polymeric dyes with spacing linker groups
WO2017197014A2 (en) 2016-05-10 2017-11-16 Sony Corporation Compositions comprising a polymeric dye and a cyclodextrin and uses thereof
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WO2017197144A1 (en) 2016-05-11 2017-11-16 Sony Corporation Ultra bright dimeric or polymeric dyes
US11377563B2 (en) 2016-06-06 2022-07-05 Sony Corporation Ionic polymers comprising fluorescent or colored reporter groups
KR20200067132A (ko) 2017-10-05 2020-06-11 소니 주식회사 프로그램가능한 중합체성 약물
US11931419B2 (en) 2017-11-16 2024-03-19 Sony Group Corporation Programmable polymeric drugs
US11874280B2 (en) 2018-03-19 2024-01-16 Sony Group Corporation Use of divalent metals for enhancement of fluorescent signals
JP2021518410A (ja) 2018-03-21 2021-08-02 ソニーグループ株式会社 リンカー基を有するポリマータンデム色素
EP3814366A1 (en) 2018-06-27 2021-05-05 Sony Corporation Polymeric dyes with linker groups comprising deoxyribose
WO2020139767A1 (en) * 2018-12-28 2020-07-02 Beckman Coulter, Inc. Methods for enhanced detection of hemoglobin
KR20230012097A (ko) 2019-09-26 2023-01-25 소니그룹주식회사 링커 그룹을 갖는 중합체성 탠덤 염료
CN111239124A (zh) * 2020-03-06 2020-06-05 中国药科大学 一种利用二硫化铂的过氧化氢比色检测法
CN113533704A (zh) * 2021-06-21 2021-10-22 南京市第一医院 一种呕吐物隐血检测装置及方法

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DE2235127C2 (de) * 1972-07-18 1974-08-08 Boehringer Mannheim Gmbh, 6800 Mannheim Diagnostisches Mittel zum Nachweis von Blut und anderen peroxidatisch wirksamen Substanzen in Körperflüssigkeiten
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Also Published As

Publication number Publication date
KR910014703A (ko) 1991-08-31
ATE127851T1 (de) 1995-09-15
JP2922003B2 (ja) 1999-07-19
DK0444263T3 (da) 1995-12-04
AU623038B2 (en) 1992-04-30
EP0444263B1 (en) 1995-09-13
EP0444263A1 (en) 1991-09-04
JPH04213063A (ja) 1992-08-04
CA2025803A1 (en) 1991-07-31
DE69022393D1 (de) 1995-10-19
DE69022393T2 (de) 1996-03-28
KR0163793B1 (ko) 1999-03-30
US5318894A (en) 1994-06-07
US5362633A (en) 1994-11-08
AU6366190A (en) 1991-08-01
ES2078934T3 (es) 1996-01-01

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